3.4.11.22: aminopeptidase I

This is an abbreviated version!
For detailed information about aminopeptidase I, go to the full flat file.

Word Map on EC 3.4.11.22

3.4.11.22

spondylitis

ankylosing

trim

aminopeptidases

histocompatibility

vacuole

hla-b27

autoimmune

psoriasis

eraps

cargo

cytoplasm-to-vacuole

peptidome

macroautophagy

spondyloarthritis

allotypes

oxytocinase

bestatin

double-membrane

maltase

exopeptidase

immunopeptidome

tnfaip3

as-associated

antigen-processing

birdshot

medicine

traf3ip2

autoinflammatory

analysis

nutrition

Reaction

Release of an N-terminal amino acid, preferably a neutral or hydrophobic one, from a polypeptide. Aminoacyl-arylamides are poor substrates =

Synonyms

A-LAP, AAP, Actinase AS, adipocyte-derived leucine amino-peptidase, Aeromonas proteolytica aminopeptidase, alpha-Aminoacyl-peptide hydrolase, Aminooligopeptidase, Aminopeptidase, aminopeptidase (I), aminopeptidase 1, aminopeptidase ERAP1, aminopeptidase I, aminopeptidase II, Aminopeptidase III, aminopeptidase IV, aminopeptidase regulator of TNFR1 shedding, Aminopeptidase yscI, Aminopeptidase yscII, Aminopeptidase yscXVI, Aminopolypeptidase, Amylorhizin aminopeptidase, Amylorizin, AP, APE1, Ape2 aminopeptidase, API, ARTS-1, Bacillus aminopeptidase I, ColAP, cold-active aminopeptidase, endoplasmic resticulum aminopeptidase associated with antigen processing, endoplasmic reticulum aminopeptidase, endoplasmic reticulum aminopeptidase 1, endoplasmic reticulum aminopeptidase associated with antigen presentation, ER aminopeptidase, ER aminopeptidase 1, ER aminopeptidase associated with antigen processing, ERAAP, ERAP1, Jc-peptidase, L-aminopeptidase, LAP, LAP II, LAP IV, LAP4, LAPase, LAPIV, Leu.AP, Leucin aminopeptidase V, leucine aminopeptidase, leucine aminopeptidase II, Leucine aminopeptidase IV, leucine-aminopeptidase, Leucineaminopeptidase I, Leucyl aminopeptidase, Metallo aminopeptidase, More, non-specific monoaminopeptidase, pApe1p, PILS-AP, Pj-peptidase, Polypeptidase, puromycin-insensitive leucyl-specific aminopeptidase, thermophilic aminopeptidase, vacuolar aminopeptidase 1, vacuolar aminopeptidase I, Yeast aminopeptidase I, YKL103C, yscI

ECTree

3 Hydrolases

3.4 Acting on peptide bonds (peptidases)

3.4.11 Aminopeptidases

3.4.11.22 aminopeptidase I

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Results	in table
6	Activating Compound
15	AA Sequence
8	Application
1	CAS Registry Number
17	Cloned(Commentary)
5	Crystallization (Commentary)
988	Disease/ Diagnostics
1	Expression
13	General Information
126	Inhibitors
12	Ki Value [mM]
57	KM Value [mM]
43	Localization
35	Metals/Ions
42	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
1	Organic Solvent Stability
135	Organism
39	PDB ID
21	pH Optimum
3	pH Range
3	pH Stability
2	pI Value
10	Posttranslational Modification
10	Protein Variants
29	Purification (Commentary)
7	Reaction
2	Reaction Type
66	Reference
29	Source Tissue
14	Specific Activity [micromol/min/mg]
3	Storage Stability
208	Substrates and Products (Substrate)
27	Subunits
122	Synonyms
18	Temperature Optimum [°C]
3	Temperature Range [°C]
14	Temperature Stability [°C]
46	Turnover Number [1/s]

Sequence

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Sequence on EC 3.4.11.22 - aminopeptidase I

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P14904 pBLAST

AMPL_YEAST

Saccharomyces cerevisiae (strain ATCC 204508 / S288c)

514

57093

Swiss-Prot