3.4.11.18: methionyl aminopeptidase
This is an abbreviated version!
For detailed information about methionyl aminopeptidase, go to the full flat file.
Word Map on EC 3.4.11.18
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3.4.11.18
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microtubule-associated
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microtubule
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dendritic
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hippocampus
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tubulin
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protein-2
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tau
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cerebral
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aminopeptidases
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fumagillin
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nestin
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neurite
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cortical
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cytoskeletal
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neurofilament
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neuroprotective
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ischemia
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fibrillary
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synaptophysin
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outgrowth
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neurotrophic
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neuron-specific
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beta-tubulin
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neurogenesis
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map2
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synapsin
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antiangiogenic
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deformylase
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microtubule-binding
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calbindin
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synthesis
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dinuclear
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microsporidian
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drug development
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medicine
- 3.4.11.18
-
microtubule-associated
- microtubule
- dendritic
- hippocampus
- tubulin
- protein-2
- tau
- cerebral
- aminopeptidases
- fumagillin
- nestin
-
neurite
- cortical
- cytoskeletal
- neurofilament
-
neuroprotective
- ischemia
-
fibrillary
-
synaptophysin
-
outgrowth
-
neurotrophic
-
neuron-specific
- beta-tubulin
-
neurogenesis
- map2
- synapsin
-
antiangiogenic
-
deformylase
-
microtubule-binding
- calbindin
- synthesis
-
dinuclear
-
microsporidian
- drug development
- medicine
Reaction
release of N-terminal amino acids, preferentially methionine, from peptides and arylamides =
Synonyms
aminopeptidase, methionine, c1MetAP-Ia, c2MetAP-Ia, c3MetAP-Ib, CoCoEcMetAP, Ebp1, eMet-AP, ErbB-3 receptor binding protein, initiation factor 2 associated 67 kDa glycoprotein, L-methionine aminopeptidase, LdBPK_210960, MAP, MAP-2, MAP-Pfu, MAP11, MAP1D, mAPA, MapB, MetAP, MetAP-1, MetAP-2, MetAP-I, MetAP-II, MetAP1, MetAP1a, MetAP1b, MetAP1c, MetAP1D, MetAP2, methionine amino peptidase type 2, methionine aminopeptidase, methionine aminopeptidase 1, methionine aminopeptidase 1b, methionine aminopeptidase 2, methionine aminopeptidase AbMetAPx, methionine aminopeptidase AbMetAPy, methionine aminopeptidase II, methionine aminopeptidase type 1, methionine aminopeptidase type 1a, methionine aminopeptidase type 1c, methionine aminopeptidase type 2, methionine aminopeptidase type I, methionine aminopeptidase type II, methionine aminopeptidase type-2, methionine aminopeptidase-1, methionine aminopeptidase-2, methionine aminopetidase-2, More, p67, p67eIF2, peptidase M, PVX_094985, TM1478, type 1 methionine aminopeptidase, type 2 methionine aminopeptidase, type I MetAP, type I methionine aminopeptidase, YpdF
ECTree
3.4.11.18 methionyl aminopeptidaseAdvanced search results
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results (KCat KM Value
KCat KM Value on EC 3.4.11.18 - methionyl aminopeptidase
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kcat/KM VALUE [1/mMs-1] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
2.5
L-alanine-4-methylcoumarin-7-amide
presence of Cu2+, pH 8.0, 37°C
5.17
L-alanine-4-methylcoumarin-7-amide
presence of Ni2+, pH 8.0, 37°C
9.8
L-alanine-4-methylcoumarin-7-amide
presence of Mn2+, pH 8.0, 37°C
10
L-alanine-4-methylcoumarin-7-amide
presence of Mg2+, pH 8.0, 37°C
12
L-alanine-4-methylcoumarin-7-amide
presence of Ca2+, pH 8.0, 37°C
13.83
L-alanine-4-methylcoumarin-7-amide
presence of Co2+, pH 8.0, 37°C
153
L-Met 4-nitroanilide
presence of Co2+, pH 8.0, 22°C
171
L-Met 4-nitroanilide
presence of Ni2+, pH 8.0, 22°C
404
L-Met 4-nitroanilide
presence of Co2+, pH 8.0, 22°C
867
L-Met 4-nitroanilide
presence of Ni2+, pH 8.0, 22°C
10
L-methionine 4-nitroanilide
pH not specified in the publication, temperature not specified in the publication
10
L-methionine 4-nitroanilide
mutant F309M, pH not specified in the publication, temperature not specified in the publication
128
L-methionine 4-nitroanilide
wild-type, pH not specified in the publication, temperature not specified in the publication
0.41
L-methionine-4-methylcoumarin-7-amide
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recombinant isozyme MetAP1a in presence of Mn2+
0.87
L-methionine-4-methylcoumarin-7-amide
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recombinant isozyme MetAP1a in presence of Fe2+
4.39
L-methionine-4-methylcoumarin-7-amide
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recombinant isozyme MetAP1a in presence of Co2+
40.91
L-methionine-4-methylcoumarin-7-amide
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recombinant isozyme MetAP1a in presence of Ni2+
0.00033
Met-4-methylcoumaryl-7-amide
after removal of divalent metal ions activated with 0.020 mM Mn2+, pH not specified in the publication, temperature not specified in the publication
0.000479
Met-4-methylcoumaryl-7-amide
after removal of divalent metal ions activated with 0.020 mM Mn2+, pH not specified in the publication, temperature not specified in the publication
0.000948
Met-4-methylcoumaryl-7-amide
after removal of divalent metal ions activated with 0.020 mM Co2+, pH not specified in the publication, temperature not specified in the publication
0.00105
Met-4-methylcoumaryl-7-amide
after removal of divalent metal ions activated with 0.020 mM Co2+, pH not specified in the publication, temperature not specified in the publication
0.0017
Met-4-methylcoumaryl-7-amide
after removal of divalent metal ions activated with 0.0025 mM Fe2+, pH not specified in the publication, temperature not specified in the publication
0.00217
Met-4-methylcoumaryl-7-amide
after removal of divalent metal ions activated with 0.020 mM Ni2+, pH not specified in the publication, temperature not specified in the publication
0.00275
Met-4-methylcoumaryl-7-amide
after removal of divalent metal ions activated with 0.005 mM Ni2+, pH not specified in the publication, temperature not specified in the publication
0.00278
Met-4-methylcoumaryl-7-amide
after removal of divalent metal ions activated with 0.0025 mM Fe2+, pH not specified in the publication, temperature not specified in the publication
