3.4.11.18: methionyl aminopeptidase

This is an abbreviated version!
For detailed information about methionyl aminopeptidase, go to the full flat file.

Reaction

release of N-terminal amino acids, preferentially methionine, from peptides and arylamides =

Synonyms

aminopeptidase, methionine, c1MetAP-Ia, c2MetAP-Ia, c3MetAP-Ib, CoCoEcMetAP, Ebp1, eMet-AP, ErbB-3 receptor binding protein, initiation factor 2 associated 67 kDa glycoprotein, L-methionine aminopeptidase, LdBPK_210960, MAP, MAP-2, MAP-Pfu, MAP11, MAP1D, mAPA, MapB, MetAP, MetAP-1, MetAP-2, MetAP-I, MetAP-II, MetAP1, MetAP1a, MetAP1b, MetAP1c, MetAP1D, MetAP2, methionine amino peptidase type 2, methionine aminopeptidase, methionine aminopeptidase 1, methionine aminopeptidase 1b, methionine aminopeptidase 2, methionine aminopeptidase AbMetAPx, methionine aminopeptidase AbMetAPy, methionine aminopeptidase II, methionine aminopeptidase type 1, methionine aminopeptidase type 1a, methionine aminopeptidase type 1c, methionine aminopeptidase type 2, methionine aminopeptidase type I, methionine aminopeptidase type II, methionine aminopeptidase type-2, methionine aminopeptidase-1, methionine aminopeptidase-2, methionine aminopetidase-2, More, p67, p67eIF2, peptidase M, PVX_094985, TM1478, type 1 methionine aminopeptidase, type 2 methionine aminopeptidase, type I MetAP, type I methionine aminopeptidase, YpdF

ECTree

     3 Hydrolases

         3.4 Acting on peptide bonds (peptidases)

             3.4.11 Aminopeptidases

                3.4.11.18 methionyl aminopeptidase

Advanced search results

Do not include text mining results

Include results (more...)

Include results (more...)

Results	in table
1	Activating Compound
72315	AA Sequence
14	Application
1	CAS Registry Number
63	Cloned(Commentary)
38	Crystallization (Commentary)
843	Disease/ Diagnostics
4	Expression
16	General Information
1	General Stability
694	IC50 Value
955	Inhibitors
67	kcat/KM [mM/s]
116	Ki Value [mM]
130	KM Value [mM]
7	Localization
154	Metals/Ions
49	Molecular Weight [Da]
26	Natural Substrates/ Products (Substrates)
244	Organism
2	Pathway
198	PDB ID
23	pH Optimum
7	pH Range
5	pI Value
1	Posttranslational Modification
110	Protein Variants
45	Purification (Commentary)
2	Reaction
1	Reaction Type
206	Reference
70	Source Tissue
43	Specific Activity [micromol/min/mg]
1	Storage Stability
295	Substrates and Products (Substrate)
40	Subunits
262	Synonyms
12	Temperature Optimum [°C]
4	Temperature Range [°C]
7	Temperature Stability [°C]
124	Turnover Number [1/s]

Expression

print visible entries

print all entries

Go back to the abbreviated version
of the Enzyme Summary Page.

Expression on EC 3.4.11.18 - methionyl aminopeptidase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.

top print hide Go to Expression Search

Please wait a moment until the data is sorted. This message will disappear when the data is sorted.

EXPRESSION

ORGANISM

UNIPROT

LITERATURE

expressed preferentially in cord blood CD34+ cells

Homo sapiens

-

717428

low temperature, abscisic acid treatment

Hordeum vulgare

E0A9F0

718239

the 3,5-bis(benzylidene)-4-piperidone derivative 2-(3-[3,5-bis[4-nitrobenzylidene]-4-oxopiperidin-1-yl]-3-oxopropylsulfanyl) ethanesulfonic acid, or NC2213, downregulates the enzyme in HT-29 cells

Homo sapiens

-

709910

ubiquitous at 6 hours postfertilization, predominantly in eye, brain and intersomitic regions at 2 hours postfertilization, also in developing heart at 30 hours postfertilization

Danio rerio

-

717428