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3.4.11.16: Xaa-Trp aminopeptidase

This is an abbreviated version!
For detailed information about Xaa-Trp aminopeptidase, go to the full flat file.

Word Map on EC 3.4.11.16

Reaction

Release of a variety of N-terminal residues (especially glutamate and leucine) from peptides, provided tryptophan (or at least phenylalanine or tyrosine) is the penultimate residue. Also acts on Glu-/-Trp, Leu-/-Trp and a number of other dipeptides =

Synonyms

aminopeptidase W, aminopeptidase X-Trp

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.11 Aminopeptidases
                3.4.11.16 Xaa-Trp aminopeptidase

Substrates Products

Substrates Products on EC 3.4.11.16 - Xaa-Trp aminopeptidase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
Ala-Trp + H2O
Ala + Trp
show the reaction diagram
-
-
-
ir
alpha-Asp-Phe + H2O
Asp + Phe
show the reaction diagram
alpha-Asp-Phe-Met + H2O
Asp + Phe-Met
show the reaction diagram
alpha-Asp-Phe-NH2 + H2O
Asp + Phe-NH2
show the reaction diagram
Arg-Trp + H2O
Arg + Trp
show the reaction diagram
-
-
-
ir
Asp-Phe + H2O
Asp + Phe
show the reaction diagram
-
-
-
ir
Asp-Phe-NH2 + H2O
Asp + Phe-NH2
show the reaction diagram
-
-
-
-
?
aspartame + H2O
?
show the reaction diagram
-
-
-
-
?
Glu-Trp + H2O
Glu + Trp
show the reaction diagram
Glu-Tyr + H2O
Glu + Tyr
show the reaction diagram
-
-
-
ir
Gly-Trp + H2O
Gly + Trp
show the reaction diagram
Gly-Tyr + H2O
Gly + Tyr
show the reaction diagram
-
-
-
ir
Ile-Phe + H2O
Ile + Phe
show the reaction diagram
-
-
-
ir
Ile-Trp + H2O
Ile + Trp
show the reaction diagram
-
-
-
ir
Leu-enkephalin + H2O
Leu + enkephalin
show the reaction diagram
-
low activity
-
ir
Leu-Phe + H2O
Leu + Phe
show the reaction diagram
-
-
-
ir
Leu-Trp + H2O
Leu + Trp
show the reaction diagram
Leu-Trp-Leu + H2O
Leu + Trp-Leu
show the reaction diagram
Leu-Trp-Met-Arg + H2O
Leu + Trp-Met-Arg
show the reaction diagram
Leu-Tyr + H2O
Leu + Tyr
show the reaction diagram
-
-
-
ir
Peptides + H2O
?
show the reaction diagram
Phe-Phe + H2O
Phe + Phe
show the reaction diagram
-
-
-
ir
Phe-Trp + H2O
Phe + Trp
show the reaction diagram
-
-
-
ir
Phe-Tyr + H2O
Phe + Tyr
show the reaction diagram
-
-
-
ir
Pro-Trp + H2O
Pro + Trp
show the reaction diagram
-
-
-
ir
Trp-Phe + H2O
Trp + Phe
show the reaction diagram
-
-
-
ir
Trp-Trp + H2O
Trp + Trp
show the reaction diagram
-
-
-
ir
Tyr-Leu + H2O
Tyr + Leu
show the reaction diagram
-
-
-
ir
Tyr-Phe + H2O
Tyr + Phe
show the reaction diagram
-
-
-
ir
Val-Trp + H2O
Val + Trp
show the reaction diagram
-
-
-
ir
additional information
?
-