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3.4.11.16: Xaa-Trp aminopeptidase

This is an abbreviated version!
For detailed information about Xaa-Trp aminopeptidase, go to the full flat file.

Word Map on EC 3.4.11.16

Reaction

Release of a variety of N-terminal residues (especially glutamate and leucine) from peptides, provided tryptophan (or at least phenylalanine or tyrosine) is the penultimate residue. Also acts on Glu-/-Trp, Leu-/-Trp and a number of other dipeptides =

Synonyms

aminopeptidase W, aminopeptidase X-Trp

ECTree

     3 Hydrolases
         3.4 Acting on peptide bonds (peptidases)
             3.4.11 Aminopeptidases
                3.4.11.16 Xaa-Trp aminopeptidase

Natural Substrates Products

Natural Substrates Products on EC 3.4.11.16 - Xaa-Trp aminopeptidase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
Peptides + H2O
?
show the reaction diagram
additional information
?
-
-
may be involved in neuropeptide metabolism, may play a minor role in the intestinal metabolism of the artificial sweetener aspartame
-
-
?