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3.3.2.13: chorismatase

This is an abbreviated version!
For detailed information about chorismatase, go to the full flat file.

Word Map on EC 3.3.2.13

Reaction

chorismate
+
H2O
=
(4R,5R)-4,5-dihydroxycyclohexa-1(6),2-diene-1-carboxylate
+
pyruvate

Synonyms

CH-fkbo, chorismatases/chorismate hydrolase, chorismate/3,4-dihydroxycyclohexa-1,5-dienoate synthase, fkbO, rapK

ECTree

     3 Hydrolases
         3.3 Acting on ether bonds
             3.3.2 Ether hydrolases
                3.3.2.13 chorismatase

Engineering

Engineering on EC 3.3.2.13 - chorismatase

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PROTEIN VARIANTS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
A244G
site-directed mutagenesis
V209Q
site-directed mutagenesis
F226A
the mutant shows 2.5% activity compared to the wild type enzyme
R228A
the mutant shows 224.5% activity compared to the wild type enzyme
Y215F
the mutant shows 12% activity compared to the wild type enzyme