3.3.2.11: cholesterol-5,6-oxide hydrolase
This is an abbreviated version!
For detailed information about cholesterol-5,6-oxide hydrolase, go to the full flat file.
Word Map on EC 3.3.2.11
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3.3.2.11
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anti-estrogenic
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oxysterols
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diphenylmethane
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hetero-oligomeric
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hormonotherapy
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medicine
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drug development
- 3.3.2.11
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anti-estrogenic
- oxysterols
- diphenylmethane
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hetero-oligomeric
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hormonotherapy
- medicine
- drug development
Reaction
Synonyms
anti-estrogen binding site, CEHase, ChEH, cholEH, cholesterol 5alpha,6alpha-oxide hydrolase, cholesterol epoxide hydrolase, cholesterol oxide hydrolase, cholesterol-5,6-epoxide hydrolase, cholesterol-epoxide hydrolase, EH_CH
ECTree
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Activating Compound
Activating Compound on EC 3.3.2.11 - cholesterol-5,6-oxide hydrolase
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acetonitrile
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maximal enzyme activity at 6.25% v/v, 19% of maximal activity at 1.25% v/v, 50% of maximal activity at 12.5% v/v, no activity at 18.8% v/v
additional information
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no effect by 5,6alpha-epoxy-5alpha-cholestan-3beta-ol in vivo, and by EDTA and 2,2-dipyridyl, preferred buffer is 300 mM potassium phosphate at pH 7.4 and 37°C, low activity in Tris and HEPES buffers
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