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3.3.2.10: soluble epoxide hydrolase

This is an abbreviated version!
For detailed information about soluble epoxide hydrolase, go to the full flat file.

Word Map on EC 3.3.2.10

Reaction

an epoxide
+
H2O
=
a glycol

Synonyms

AnEH, BNSEH1, CEH, Cterm-EH, Cytosolic epoxide hydrolase, EC 3.1.3.76, EC 3.3.2.3, EC 4.2.1.63, EC 4.2.1.64, EET-metabolizing enzyme, EH, EH3, EPHX2, EPHX3, epoxide hydrolase 1, epoxide hydrolase 2, epoxide hydrolase-3, epoxyeicosatrienonic acid-metabolizing enzyme, EPXH1, EPXH2, EPXH2B, hepoxilin hydrolase, hsEH, mEH, More, PNSO hydrolase, PsEH, s-EH, SEH, soluble epoxide hydrolase, soluble-type epoxide hydrolase, SPEH1, SPEH2, TESO hydrolase, TSO hydrolase

ECTree

     3 Hydrolases
         3.3 Acting on ether bonds
             3.3.2 Ether hydrolases
                3.3.2.10 soluble epoxide hydrolase

Specific Activity

Specific Activity on EC 3.3.2.10 - soluble epoxide hydrolase

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SPECIFIC ACTIVITY [µmol/min/mg]
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0.00017
-
liver cytosol, substrate trans-beta-methyl-styrene oxide
0.00049
-
liver cytosol, substrate trans-beta-methyl-styrene oxide
0.00051
-
epididymis cytosol
0.00062 - 0.00852
-
diseased kidney, cell-free enzyme extract
0.001
-
liver cytosol
0.00122 - 0.00549
-
healthy kidney, cell-free enzyme extract
0.0014
-
crude potato enzyme extract
0.00157
-
liver cytosol, substrate allylbenzene oxide
0.00189
-
liver cytosol, substrate trans-bety-methyl-styrene oxide
0.00264
-
liver cytosol, substrate allylbenzene oxide
0.0027
-
kidney cytosol
0.003
purified recombinant enzyme, substrate trans-9,10-epoxystearate
0.0064
-
epoxide hydrolysis
0.007
-
liver cytosol, substrate allylbenzene oxide
0.0078
-
purified enzyme, substrate 4-nitrostyrene 7,8-oxide
0.01
-
purified recombinant enzyme, substrate cyano(6-methoxy-2-naphthyl)methyl (3,3-dimethyloxiran-2-yl)methyl carbonate
0.012
purified recombinant enzyme, substrate cis-8,9-epoxyeicosatrienoic acid or cis-11,12-epoxyeicosatrienoic acid
0.025
purified recombinant enzyme, substrate cis-14,15-epoxyeicosatrienoic acid
0.033
(5Z,11Z,14Z)-8,9-epoxyeicosa-8,11,14-trienoic acid
0.051
-
purified enzyme, substrate trans-8-ethylstyrene 7,8-oxide
0.063
-
recombinant enzyme in crude enzyme extract
0.12
-
purified recombinant enzyme, substrate cyano(6-methoxy-2-naphthyl)methyl (3,3-dimethyloxiran-2-yl)methyl carbonate
0.13
-
purified recombinant enzyme, substrate cyano(6-methoxy-2-naphthyl)methyl (3-ethyloxiran-2-yl)methyl carbonate
0.145
-
-
0.167
-
-
0.21
-
purified recombinant enzyme, substrate cyano(6-methoxy-2-naphthyl)methyl (3-phenyloxiran-2-yl)acetate
0.26
-
purified recombinant enzyme, substrate cyano(6-methoxy-2-naphthyl)methyl (3-propyloxiran-2-yl)methyl carbonate
0.28
-
purified recombinant enzyme, substrate cyano(2-methoxy-naphthalen-6-yl)methyl trans-2-(3-propyloxiran-2-yl) acetate
0.33
(5Z,8Z,11Z)-14,15-epoxyeicosa-5,8,11-trienoic acid
0.36
-
purified recombinant enzyme, substrate [3-(4-chlorophenyl)oxiran-2-yl]methyl cyano(6-methoxy-2-naphthyl)methyl carbonate
0.38
-
purified recombinant enzyme, substrate cyano(6-methoxy-2-naphthyl)methyl [3-(4-nitrophenyl)oxiran-2-yl]methyl carbonate
0.41
-
purified recombinant enzyme, substrate cyano(6-methoxy-2-naphthyl)methyl (3-ethyloxiran-2-yl)methyl carbonate
0.49
(5Z,8Z,13Z)-11,12-epoxyeicosa-5,8,14-trienoic acid
0.53
-
purified recombinant enzyme, substrate cyano(2-methoxy-naphthalen-6-yl)methyl trans-2-(3-propyloxiran-2-yl) acetate
0.574
-
-
0.71
-
purified recombinant enzyme, substrate cyano(6-methoxy-2-naphthyl)methyl (3-phenyloxiran-2-yl)acetate
0.78
-
purified recombinant enzyme, substrate cyano(6-methoxy-2-naphthyl)methyl (3-phenyloxiran-2-yl)methyl carbonate
0.823
purified recombinant enzyme, substrate trans-1,3-diphenylpropene oxide
1.02
-
purified recombinant enzyme, substrate cyano(6-methoxy-2-naphthyl)methyl (3-propyloxiran-2-yl)methyl carbonate
1.04
-
purified recombinant enzyme, substrate [3-(4-chlorophenyl)oxiran-2-yl]methyl cyano(6-methoxy-2-naphthyl)methyl carbonate
1.33
-
enzyme from clofibrate-treated mice
1.46
-
-
2.69
-
purified recombinant enzyme, substrate cyano(6-methoxy-2-naphthyl)methyl (3-phenyloxiran-2-yl)methyl carbonate
3.1
trans-1,3-diphenylpropene oxide
3.315
recombinant enzyme expressed in Escherichia coli
3.91
cress
-
-
36.29
purified recombinant full-length enzyme, pH 7.4, 30°C
4.044
recombinant enzyme expressed in Sf9 cells
4.2
(9Z)-12,13-epoxyoctadec-9-enoic acid
4.8
(12Z)-9,10-epoxyoctadec-12-enoic acid
67.64
purified recombinant C-terminal domain, pH 7.4, 30°C
additional information