3.3.2.10: soluble epoxide hydrolase

This is an abbreviated version!
For detailed information about soluble epoxide hydrolase, go to the full flat file.

Word Map on EC 3.3.2.10

3.3.2.10

epoxyeicosatrienoic

arachidonic

diol

s-transferase

hydrolases

hypertension

benzoapyrene

epoxygenase

styrene

dihydroxyeicosatrienoic

enantioselectivity

phenobarbital

dhets

trans-stilbene

leukotriene

eicosanoids

drug-metabolizing

cyp1a1

3-methylcholanthrene

o-deethylase

oxylipins

xenobiotic-metabolizing

dihydrodiols

enantiopure

ethoxyresorufin

lta4

glycidyl

arene

urea-based

cyclohexene

ethoxycoumarin

medicine

beta-naphthoflavone

oxirane

20-hydroxyeicosatetraenoic

udp-glucuronyltransferase

20-hete

cyp2j2

udp-glucuronosyl

1-naphthol

aminopyrine

edhfs

analysis

radiobacter

3-methylcholanthrene-treated

butadiene

udpgt

hydroxyeicosatetraenoic

epichlorohydrin

aldrin

synthesis

pentoxyresorufin

drug development

agriculture

adamantyl

pharmacology

Reaction

Synonyms

AnEH, BNSEH1, CEH, Cterm-EH, Cytosolic epoxide hydrolase, EC 3.1.3.76, EC 3.3.2.3, EC 4.2.1.63, EC 4.2.1.64, EET-metabolizing enzyme, EH, EH3, EPHX2, EPHX3, epoxide hydrolase 1, epoxide hydrolase 2, epoxide hydrolase-3, epoxyeicosatrienonic acid-metabolizing enzyme, EPXH1, EPXH2, EPXH2B, hepoxilin hydrolase, hsEH, mEH, More, PNSO hydrolase, PsEH, s-EH, SEH, soluble epoxide hydrolase, soluble-type epoxide hydrolase, SPEH1, SPEH2, TESO hydrolase, TSO hydrolase

ECTree

3 Hydrolases

3.3 Acting on ether bonds

3.3.2 Ether hydrolases

3.3.2.10 soluble epoxide hydrolase

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Results	in table
173	Activating Compound
2387	AA Sequence
67	Application
1	CAS Registry Number
61	Cloned(Commentary)
16	Crystallization (Commentary)
2131	Disease/ Diagnostics
12	Expression
87	General Information
1188	IC50 Value
2130	Inhibitors
30	kcat/KM [mM/s]
63	Ki Value [mM]
109	KM Value [mM]
242	Localization
60	Metals/Ions
103	Molecular Weight [Da]
167	Natural Substrates/ Products (Substrates)
354	Organism
1	Oxidation Stability
13	Pathway
127	PDB ID
72	pH Optimum
15	pH Range
2	pH Stability
18	pI Value
2	Posttranslational Modification
148	Protein Variants
54	Purification (Commentary)
21	Reaction
317	Reference
433	Source Tissue
69	Specific Activity [micromol/min/mg]
7	Storage Stability
758	Substrates and Products (Substrate)
114	Subunits
267	Synonyms
1	Systematic Name
60	Temperature Optimum [°C]
4	Temperature Range [°C]
42	Temperature Stability [°C]
55	Turnover Number [1/s]

Molecular Weight

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Molecular Weight on EC 3.3.2.10 - soluble epoxide hydrolase

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100000

Aspergillus niger

Q9UR30

recombinant enzyme, gel filtration

660943

110000

Oryctolagus cuniculus

equilibrium sedimentation

120000

130000

140000

gel filtration, monomeric or dimeric enzyme, dependent on conditions

185000

gel filtration

24000

recombinant enzyme, SDS-PAGE

32000

2 * 32000, SDS-PAGE

32140

x * 32140, calculation from nucleotide sequence

208925

33000

Glycine max

O49857

1 * 33000, recombinant enzyme, SDS-PAGE, 1 * 36171, recombinant and native enzymes, mass spectrometry, 1 * 36000, native enzyme, sedimentation equilibrium analysis

340000

gel filtration

35000

36000

36171

1 * 33000, recombinant enzyme, SDS-PAGE, 1 * 36171, recombinant and native enzymes, mass spectrometry, 1 * 36000, native enzyme, sedimentation equilibrium analysis

661622

37000

2 entries

38000

Solanum tuberosum

x * 38000, recombinant enzyme from insect cells, SDS-PAGE

38061

x * 38061, MALDI-TOF

38200

calculated from sequence

39000

1 * 39000, SDS-PAGE

40000

45000

49000

50000

x * 50000, SDS-PAGE

55000

gel filtration

57000

57900

gel filtration

58000

59000

60000

60700

uninduced murine liver, gel filtration

61500

x * 61500, SDS-PAGE

62000

62500

62600

63000

x * 63000, recombinant enzyme, SDS-PAGE

663193

63800

Strongylocentrotus purpuratus

B2MWN2, B2MWN3

predicted: 63600, SPEH1

64200

64800

x * 64800, SDS-PAGE

65000

80000

2 * 80000, SDS-PAGE, dimerization is required for enzymatic activity

732124

additional information

4 entries