3.3.2.10: soluble epoxide hydrolase
This is an abbreviated version!
For detailed information about soluble epoxide hydrolase, go to the full flat file.
Word Map on EC 3.3.2.10
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3.3.2.10
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epoxyeicosatrienoic
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arachidonic
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diol
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s-transferase
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hydrolases
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hypertension
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benzoapyrene
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epoxygenase
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styrene
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dihydroxyeicosatrienoic
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enantioselectivity
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phenobarbital
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dhets
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trans-stilbene
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leukotriene
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eicosanoids
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drug-metabolizing
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cyp1a1
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3-methylcholanthrene
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o-deethylase
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oxylipins
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xenobiotic-metabolizing
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dihydrodiols
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enantiopure
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ethoxyresorufin
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lta4
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glycidyl
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arene
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urea-based
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cyclohexene
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ethoxycoumarin
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medicine
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beta-naphthoflavone
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oxirane
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20-hydroxyeicosatetraenoic
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udp-glucuronyltransferase
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20-hete
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cyp2j2
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udp-glucuronosyl
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1-naphthol
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aminopyrine
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edhfs
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analysis
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radiobacter
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3-methylcholanthrene-treated
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butadiene
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udpgt
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hydroxyeicosatetraenoic
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epichlorohydrin
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aldrin
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synthesis
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pentoxyresorufin
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drug development
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agriculture
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adamantyl
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pharmacology
- 3.3.2.10
-
epoxyeicosatrienoic
-
arachidonic
- diol
- s-transferase
- hydrolases
- hypertension
-
benzoapyrene
- epoxygenase
- styrene
-
dihydroxyeicosatrienoic
-
enantioselectivity
- phenobarbital
-
dhets
- trans-stilbene
-
leukotriene
-
eicosanoids
-
drug-metabolizing
- cyp1a1
- 3-methylcholanthrene
-
o-deethylase
- oxylipins
-
xenobiotic-metabolizing
-
dihydrodiols
-
enantiopure
-
ethoxyresorufin
- lta4
-
glycidyl
- arene
-
urea-based
- cyclohexene
-
ethoxycoumarin
- medicine
- beta-naphthoflavone
-
oxirane
-
20-hydroxyeicosatetraenoic
-
udp-glucuronyltransferase
- 20-hete
- cyp2j2
-
udp-glucuronosyl
- 1-naphthol
- aminopyrine
-
edhfs
- analysis
- radiobacter
-
3-methylcholanthrene-treated
- butadiene
-
udpgt
-
hydroxyeicosatetraenoic
- epichlorohydrin
- aldrin
- synthesis
-
pentoxyresorufin
- drug development
- agriculture
-
adamantyl
- pharmacology
Reaction
Synonyms
AnEH, BNSEH1, CEH, Cterm-EH, Cytosolic epoxide hydrolase, EC 3.1.3.76, EC 3.3.2.3, EC 4.2.1.63, EC 4.2.1.64, EET-metabolizing enzyme, EH, EH3, EPHX2, EPHX3, epoxide hydrolase 1, epoxide hydrolase 2, epoxide hydrolase-3, epoxyeicosatrienonic acid-metabolizing enzyme, EPXH1, EPXH2, EPXH2B, hepoxilin hydrolase, hsEH, mEH, More, PNSO hydrolase, PsEH, s-EH, SEH, soluble epoxide hydrolase, soluble-type epoxide hydrolase, SPEH1, SPEH2, TESO hydrolase, TSO hydrolase
ECTree
3.3.2.10 soluble epoxide hydrolaseAdvanced search results
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results (Activating Compound
Activating Compound on EC 3.3.2.10 - soluble epoxide hydrolase
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ACTIVATING COMPOUND 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
1-Benzylimidazole
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activates mirosomal activity with styrene oxide as substrate
Clofibrate
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slight inhibition of enzyme from untreated mice, slight activation of the enzyme from clofibrate-treated mice
Tween-80
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when the cosolvent DMSO is replaced by an emulsifier (Tween-80, 0.5% w/v) as an alternative additive to help disperse the water-insoluble substrate, the apparent activity of the epoxide hydrolase significantly increased by about 1.8fold
additional information
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inducible isozymes can be induced by e.g. fruit ripening, germination, host-defense, exogenous exposure to hormones, growth
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additional information
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inducible isozymes can be induced by e.g. fruit ripening, germination, host-defense, exogenous exposure to hormones, growth
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additional information
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inducible isozymes can be induced by e.g. fruit ripening, germination, host-defense, growth, the enzyme is not affected by cytokinin, abscisic acid, 6-benzylaminopurine, or gibberellin, while auxin, 2,4-dichlorophenoxy acetic acid, and naphthalene acetic acid induce the enzyme in stem and leaves, drought stress slightly induces the enzmye in stem and leaves
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additional information
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inducible isozymes can be induced by e.g. fruit ripening, germination, host-defense, exogenous exposure to hormones, growth
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additional information
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inducible isozymes can be induced by e.g. fruit ripening, germination, host-defense, exogenous exposure to hormones, growth, pathogenic fungus infection induces the enzyme in leaves
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additional information
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inducible isozymes can be induced by e.g. fruit ripening, germination, host-defense, exogenous exposure to hormones, growth
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additional information
ethylene induces the enzyme expression in stem and seeds, not in leaves
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additional information
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ethylene induces the enzyme expression in stem and seeds, not in leaves
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additional information
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inducible isozymes can be induced by e.g. fruit ripening, germination, host-defense, exogenous exposure to hormones, growth, ethylene induces the enzyme in germinating seeds
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additional information
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the enzyme is induced by several substances, e.g. 2-acetylfluorene, alpha-1-acetylmethadol, butylated hydroxyanisole, butylated hydroxytoluene, chalcone, gamma-chlordane, 1,2-dibromo-3-chloropropane, ethoxyquin, isosafrole, 3-methylcholanthrene, alpha-naphthoflavone, phenobarbital, polychlorinated and/or polybrominated biphenyls, pregnenolone-16alpha-carbonitrile, and trans-stilbene oxide
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additional information
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the enzyme is induced by several substances, e.g. 2-acetylfluorene, alpha-1-acetylmethadol, butylated hydroxyanisole, butylated hydroxytoluene, chalcone, gamma-chlordane, 1,2-dibromo-3-chloropropane, ethoxyquin, isosafrole, 3-methylcholanthrene, alpha-naphthoflavone, phenobarbital, polychlorinated and/or polybrominated biphenyls, pregnenolone-16alpha-carbonitrile, and trans-stilbene oxide
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additional information
-
inducible isozymes can be induced by e.g. fruit ripening, germination, host-defense, exogenous exposure to hormones, growth
-
additional information
-
the enzyme is induced by several substances, e.g. 2-acetylfluorene, alpha-1-acetylmethadol, butylated hydroxyanisole, butylated hydroxytoluene, chalcone, gamma-chlordane, 1,2-dibromo-3-chloropropane, ethoxyquin, isosafrole, 3-methylcholanthrene, alpha-naphthoflavone, phenobarbital, polychlorinated and/or polybrominated biphenyls, pregnenolone-16alpha-carbonitrile, and trans-stilbene oxide
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additional information
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inducible isozymes can be induced by e.g. fruit ripening, germination, host-defense, exogenous exposure to hormones, growth, viral infection of the aerial body and the plant induces the enzyme
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additional information
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the enzyme is induced by several substances, e.g. 2-acetylfluorene, alpha-1-acetylmethadol, butylated hydroxyanisole, butylated hydroxytoluene, chalcone, gamma-chlordane, 1,2-dibromo-3-chloropropane, ethoxyquin, isosafrole, 3-methylcholanthrene, alpha-naphthoflavone, phenobarbital, polychlorinated and/or polybrominated biphenyls, pregnenolone-16alpha-carbonitrile, and trans-stilbene oxide
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additional information
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inducible isozymes can be induced by e.g. fruit ripening, germination, host-defense, exogenous exposure to hormones, growth
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additional information
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maximal activity with dimethyl formamide as co-solvent, effects of solvents on enzyme activity, overview
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additional information
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the enzyme is induced by clofibrate in liver not in epididymis
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additional information
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the enzyme is induced by several substances, e.g. 2-acetylfluorene, alpha-1-acetylmethadol, butylated hydroxyanisole, butylated hydroxytoluene, chalcone, gamma-chlordane, 1,2-dibromo-3-chloropropane, ethoxyquin, isosafrole, 3-methylcholanthrene, alpha-naphthoflavone, phenobarbital, polychlorinated and/or polybrominated biphenyls, pregnenolone-16alpha-carbonitrile, and trans-stilbene oxide
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additional information
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sEH is specifically up-regulated by angiotensin II
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additional information
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inducible isozymes can be induced by e.g. fruit ripening, germination, host-defense, exogenous exposure to hormones, growth
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additional information
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inducible isozymes can be induced by e.g. fruit ripening, germination, host-defense, growth, the enzyme is not affected by cytokinin, abscisic acid, 6-benzylaminopurine, or gibberellin, but highly by methyl jasmonate, auxin, and ethylene, wounding induces the enzyme in leaves
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additional information
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wounding and methyl jasmonate induce enzyme expression in leaves, while abscisic acid does not
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additional information
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inducible isozymes can be induced by e.g. fruit ripening, germination, host-defense, exogenous exposure to hormones, growth
-
additional information
-
inducible isozymes can be induced by e.g. fruit ripening, germination, host-defense, exogenous exposure to hormones, growth
-
additional information
-
inducible isozymes can be induced by e.g. fruit ripening, germination, host-defense, exogenous exposure to hormones, growth
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