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3.2.2.6: ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase

This is an abbreviated version!
For detailed information about ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase, go to the full flat file.

Word Map on EC 3.2.2.6

Reaction

cyclic ADP-ribose
+
H2O
=
ADP-D-ribose

Synonyms

ADP-ribosyl cyclase, ADPR cyclase, bCD38, CD38, CD38/NAD+ glycohydrolase, NAD(P) nucleosidase, NAD(P)+ glycohydrolase, NAD(P)+-glycohydrolase, NAD(P)-glycohydrolase, NAD(P)ase, NAD+ glycohydrolase, NADase, nicotinamide adenine dinucleotide (phosphate) glycohydrolase, nicotinamide adenine dinucleotide (phosphate) nucleosidase, nucleosidase, nicotinamide adenine dinucleotide (phosphate), triphosphopyridine nucleotidase

ECTree

     3 Hydrolases
         3.2 Glycosylases
             3.2.2 Hydrolysing N-glycosyl compounds
                3.2.2.6 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase

IC50 Value

IC50 Value on EC 3.2.2.6 - ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0321
5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)chromenium
Homo sapiens
-
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogene
0.0218
cyanidin
Homo sapiens
-
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogene
0.0146
delphinidin
Homo sapiens
-
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogene
0.0703
fisetinidin
Homo sapiens
-
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogene
0.0063
kuromanin
Homo sapiens
-
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogene
0.0082
luteolin
Homo sapiens
-
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogene
0.006
luteolinidin
Homo sapiens
-
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogene
0.017
malvidin
Homo sapiens
-
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogene
0.0248
myricetin
Homo sapiens
-
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogene
0.0163
pelargonidin
Homo sapiens
-
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogene
0.0209
peonidin
Homo sapiens
-
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogene
0.0392
petunidin
Homo sapiens
-
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogene
0.0486
quercetagetin
Homo sapiens
-
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogene
0.0142
quercetagetinidin
Homo sapiens
-
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogene
0.0379
quercetin
Homo sapiens
-
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogene
0.0379
robinetin
Homo sapiens
-
at 37°C in 10 mM potassium phosphate buffer, pH 7.4, containing 0.05% (w/v) emulphogene