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3.2.2.26: futalosine hydrolase

This is an abbreviated version!
For detailed information about futalosine hydrolase, go to the full flat file.

Reaction

futalosine
+
H2O
=
dehypoxanthine futalosine
 +
hypoxanthine

Synonyms

5'-methylthioadenosine nucleosidase, futalosine hydrolase, futalosine nucleosidase, MqnB, MTAN, TTHA0556

ECTree

     3 Hydrolases
         3.2 Glycosylases
             3.2.2 Hydrolysing N-glycosyl compounds
                3.2.2.26 futalosine hydrolase

Inhibitors

Inhibitors on EC 3.2.2.26 - futalosine hydrolase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
(2R)-2-[[(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]amino]-3-(methylsulfanyl)propan-1-ol
-
(2R)-2-[[(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]amino]-3-[(pyrazin-2-yl)sulfanyl]propan-1-ol
-
(2S)-2-[[(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]amino]octan-1-ol
-
(2S,3S,4R,5S)-2-(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)-5-[(methylsulfanyl)methyl]pyrrolidine-3,4-diol
-
(2S,3S,4R,5S)-2-(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)-5-[[(4-chlorophenyl)sulfanyl]methyl]pyrrolidine-3,4-diol
-
(2S,3S,4R,5S)-2-(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)-5-[[(naphthalen-1-yl)sulfanyl]methyl]pyrrolidine-3,4-diol
-
(3R,4R)-1-[(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-(hydroxymethyl)pyrrolidin-3-ol
-
(3R,4S)-1-[(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-(adamant-1-yl)sulfanyl]methyl]pyrrolidin-3-ol
-
(3R,4S)-1-[(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-([[2-(2-hydroxyethoxy)ethyl]sulfanyl]methyl)pyrrolidin-3-ol
-
(3R,4S)-1-[(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-butylpyrrolidin-3-ol
-
(3R,4S)-1-[(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-ethylpyrrolidin-3-ol
-
(3R,4S)-1-[(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-methylpyrrolidin-3-ol
-
(3R,4S)-1-[(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-propylpyrrolidin-3-ol
-
(3R,4S)-1-[(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(butylsulfanyl)methyl]pyrrolidin-3-ol
-
(3R,4S)-1-[(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(cyclohexylsulfanyl)methyl]pyrrolidin-3-ol
-
(3R,4S)-1-[(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(hexylsulfanyl)methyl]pyrrolidin-3-ol
-
(3R,4S)-1-[(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(methylsulfanyl)methyl]pyrrolidin-3-ol
-
(3R,4S)-1-[(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[(phenylsulfanyl)methyl]pyrrolidin-3-ol
-
(3R,4S)-1-[(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[2-(hexylsulfanyl)ethyl]pyrrolidin-3-ol
-
(3R,4S)-1-[(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[2-[2-(2-hydroxyethoxy)ethoxy]ethyl]pyrrolidin-3-ol
-
(3R,4S)-1-[(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[[(4-chlorophenyl)sulfanyl]methyl]pyrrolidin-3-ol
-
(3R,4S)-1-[(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-[[(pyrazin-2-yl)sulfanyl]methyl]pyrrolidin-3-ol
-
(3S,4R,5R)-2-(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)-5-(hydroxymethyl)pyrrolidine-3,4-diol
-
(3S,4R,5R)-2-[(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-5-(hydroxymethyl)pyrrolidine-3,4-diol
-
3-(3-[(3S,4R)-1-[(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-hydroxypyrrolidin-3-yl]propanoyl)benzoic acid
-
3-[3-[(2R,3R,4S,5S)-5-(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)-3,4-dihydroxypyrrolidin-2-yl]propanoyl]benzoic acid
-
7-(5-S-methyl-5-thio-beta-D-ribofuranosyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
-
hypoxanthine
-
product inhibition
[(3S,4R)-1-[(4-amino-5,7a-dihydro-4aH-pyrrolo[3,2-d]pyrimidin-7-yl)methyl]-4-hydroxypyrrolidin-3-yl]methionine
-