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3.2.2.23: DNA-formamidopyrimidine glycosylase

This is an abbreviated version!
For detailed information about DNA-formamidopyrimidine glycosylase, go to the full flat file.

Word Map on EC 3.2.2.23

Reaction

DNA containing ring-opened N7-methylguanine
+
H2O
=
deguanylated DNA
 +
2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine

Synonyms

2,6-diamino-4-hydroxy-5(N-methyl)formamidopyrimidine-DNA glycosylase, 2,6-diamino-4-hydroxy-5N-formamidopyrimidine-DNA glycosylase, 2,6-diamino-4-hydroxy-5N-methyl-formamidopyrimidine-DNA glycosylase, 8-hydroxyguanine endonuclease, 8-oxoguanine DNA glycosylase, 8-oxoguanine-DNA glycosylase, deoxyribonucleate glycosidase, DNA glycohydrolase (releasing 2,6-diamino-4-hydroxy-5-(N-methyl)-formamidopyrimidine), DNA glycosylase, endonuclease VIII-like DNA glycosylase, Fapy DNA glycosylase, Fapy-DNA glycosylase, formamidopyrimidineDNA glycosylase, formamidopyrimidine DNA glycosylase, formamidopyrimidine glycosylase, formamidopyrimidine-DNA glycosyl hydrolase, formamidopyrimidine-DNA glycosylase, formamidopyrimidine-N-glycosylase, FPG, Fpg protein, FPG-1, FPG-2, Fpg-L, glycosidase, deoxyribonucleate formamidopyrimidine, More, Mtb-Fpg1, MutM, MutM1, NEH1, NEH2, Nei, NEIL1, NEIL3, OGG1

ECTree

     3 Hydrolases
         3.2 Glycosylases
             3.2.2 Hydrolysing N-glycosyl compounds
                3.2.2.23 DNA-formamidopyrimidine glycosylase

Source Tissue

Source Tissue on EC 3.2.2.23 - DNA-formamidopyrimidine glycosylase

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SOURCE TISSUE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
SOURCE
low expression of NEH1
Manually annotated by BRENDA team
primary human diploid fibroblasts, S phase-specific expression of NEH1
Manually annotated by BRENDA team
moderate expression of NEH1
Manually annotated by BRENDA team
highest expression of NEH1 in liver, pancreas and thymus
Manually annotated by BRENDA team
moderate expression of NEH1
Manually annotated by BRENDA team
moderate expression of NEH1
Manually annotated by BRENDA team
low expression of NEH1
Manually annotated by BRENDA team
highest expression of NEH1 in liver, pancreas and thymus
Manually annotated by BRENDA team
additional information