3.2.2.21: DNA-3-methyladenine glycosylase II
This is an abbreviated version!
For detailed information about DNA-3-methyladenine glycosylase II, go to the full flat file.
Word Map on EC 3.2.2.21
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3.2.2.21
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glycosylases
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endonuclease
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8-oxoguanine
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strand
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guanine
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thymine
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mismatch
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abasic
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pyrimidine
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uracil
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duplex
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8-oxog
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excises
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cytosine
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alkyladenine
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mispairs
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mutyh
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7,8-dihydro-8-oxoguanine
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formamidopyrimidine
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hypoxanthine
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7-methylguanine
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ape1
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5-methylcytosine
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1,n6-ethenoadenine
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undamaged
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8-hydroxyguanine
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8-oxo-7,8-dihydroguanine
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formamidopyrimidine-dna
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nucleobase
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transversions
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apurinic
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uracil-dna
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n-glycosidic
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ser326cys
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etheno
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mutyh-associated
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unrepaired
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mismatch-specific
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8-oxo-7,8-dihydro-2'-deoxyguanosine
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base-excision
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5-hydroxymethyluracil
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apyrimidinic
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8-oxoguanine-dna
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premutagenic
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alkylation-induced
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ap-endonuclease
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thymine-dna
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medicine
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miscoding
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extrahelical
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methylmethane
- 3.2.2.21
- glycosylases
- endonuclease
- 8-oxoguanine
- strand
- guanine
- thymine
- mismatch
-
abasic
- pyrimidine
- uracil
- duplex
-
8-oxog
-
excises
- cytosine
-
alkyladenine
- mispairs
-
mutyh
- 7,8-dihydro-8-oxoguanine
- formamidopyrimidine
- hypoxanthine
- 7-methylguanine
- ape1
- 5-methylcytosine
- 1,n6-ethenoadenine
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undamaged
- 8-hydroxyguanine
- 8-oxo-7,8-dihydroguanine
-
formamidopyrimidine-dna
-
nucleobase
-
transversions
-
apurinic
-
uracil-dna
-
n-glycosidic
-
ser326cys
-
etheno
-
mutyh-associated
-
unrepaired
-
mismatch-specific
-
8-oxo-7,8-dihydro-2'-deoxyguanosine
-
base-excision
- 5-hydroxymethyluracil
-
apyrimidinic
-
8-oxoguanine-dna
-
premutagenic
-
alkylation-induced
- ap-endonuclease
-
thymine-dna
- medicine
-
miscoding
-
extrahelical
-
methylmethane
Reaction
Synonyms
3-methyladenine DANN glycosylase II, 3-methyladenine DNA glycosylase II, 3-methyladenine-DNA glycosidase II, 3-methyladenine-DNA glycosylase II, AAG, ALK, AlkA, AlkA protein, AlkA1, AlkA2, AlkD, alkylpurine-DNA-N-glycosylase, ANPG, deoxyribonucleate 3-methyladenine glycosidase II, DNA glycosylase, DNA-3-methyladenine glycosidase II, helix-hairpin-helix DNA glycosylase, m3A DNA glycosylase II, MAG, Mag1 protein, MPG, N-methylpurine-DNA glycosylase, TagII
ECTree
3.2.2.21 DNA-3-methyladenine glycosylase IIAdvanced search results
results (
results (KM Value
KM Value on EC 3.2.2.21 - DNA-3-methyladenine glycosylase II
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KM VALUE [mM] 
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
IMAGE
0.0000092
3-methyladenine residues in alkylated DNA
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pH 8.0, 37°C, release of 3-methyladenine
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0.000011
7-methylguanine residues in alkylated DNA
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pH 8.0, 37°C, release of 7-methylguanine
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0.0000354 - 0.042
duplex oligonucleotide substrate containing ethenoadenine and hypoxanthine
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0.000024
1,N6-ethenoadenine residues in alkylated DNA
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pH 7.5, 37°C, excision of 1, N6-ethenoadenine
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0.00004 - 0.001
1,N6-ethenoadenine residues in alkylated DNA
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pH 8.3, 37°C, release of 1,N6-ethenoadenine, wild type enzyme
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0.00006 - 0.0013
1,N6-ethenoadenine residues in alkylated DNA
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pH 8.3, 37°C, release of 1,N6-ethenoadenine, truncated mutant N-DELTA100C-DELTA18
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0.00000014
alkylated DNA
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pH 7.5, 37°C, excision of 5-hydroxymethyluracil, denatured DNA
0.000031
alkylated DNA, treated with N-methyl-N'-nitro-N-nitrosoguanidine
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pH 7.5, 37°C, excision of 7-methylguanine
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0.000053
alkylated DNA, treated with N-methyl-N'-nitro-N-nitrosoguanidine
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pH 7.5, 37°C, excision of xanthine
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0.0000354
duplex oligonucleotide substrate containing ethenoadenine and hypoxanthine
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37°C, pH 7.9
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0.0000448
duplex oligonucleotide substrate containing ethenoadenine and hypoxanthine
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37°C, pH 7.9, presence of 250 mM Mg2+
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0.0000548
duplex oligonucleotide substrate containing ethenoadenine and hypoxanthine
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37°C, pH 7.9, presence of 500 mM Mg2+
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0.042
duplex oligonucleotide substrate containing ethenoadenine and hypoxanthine
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at 37°C, in 50 mM Na-MES buffer (pH 6.1)
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