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3.2.2.15: DNA-deoxyinosine glycosylase

This is an abbreviated version!
For detailed information about DNA-deoxyinosine glycosylase, go to the full flat file.

Word Map on EC 3.2.2.15

Reaction

hypoxanthine-containing DNA
+
H2O
=
hypoxanthine
+
DNA containing an abasic site

Synonyms

bovine hypoxanthine-DNA glycosylase, deoxyribonucleic acid glycosylase, DNA(hypoxanthine) glycohydrolase, DNA(hypoxanthine)glycohydrolase, family 5 UDGb, hypoxanthine DNA glycosylase, hypoxanthine-DNA glycosylase, hypoxanthine-DNA-glycosylase, Phep_0752, SMUG2, UdgB, uracil DNA glycosylase

ECTree

     3 Hydrolases
         3.2 Glycosylases
             3.2.2 Hydrolysing N-glycosyl compounds
                3.2.2.15 DNA-deoxyinosine glycosylase

Inhibitors

Inhibitors on EC 3.2.2.15 - DNA-deoxyinosine glycosylase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Ca2+
-
higher concentrations, above 10 mM CaCl2
DNA
-
markedly inhibited by low concentrations of native DNA
dsDNA
-
AP-site containing
-
KCl
-
2fold inhibited
Mg2+
-
higher concentrations, above 20 mM MgCl2
NaCl
-
70% inhibited by addition of 0.1 M NaCl