3.2.2.14: NMN nucleosidase

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For detailed information about NMN nucleosidase, go to the full flat file.

Reaction

Synonyms

NaR nucleosidase, nicotinamide mononucleotidase, nicotinamide mononucleotide glycohydrolase, nicotinamide mononucleotide nucleosidase, NMN glycohydrolase, NMNase, NMNGhase

ECTree

     3 Hydrolases

         3.2 Glycosylases

             3.2.2 Hydrolysing N-glycosyl compounds

                3.2.2.14 NMN nucleosidase

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Results	in table
14	Activating Compound
1	AA Sequence
1	CAS Registry Number
1	General Stability
27	Inhibitors
2	Ki Value [mM]
6	KM Value [mM]
1	Localization
6	Molecular Weight [Da]
11	Natural Substrates/ Products (Substrates)
18	Organism
5	Pathway
2	pH Optimum
4	Purification (Commentary)
1	Reaction
1	Reaction Type
12	Reference
2	Source Tissue
21	Specific Activity [micromol/min/mg]
2	Storage Stability
18	Substrates and Products (Substrate)
1	Subunits
7	Synonyms
1	Systematic Name
1	Temperature Optimum [°C]

Activating Compound

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Activating Compound on EC 3.2.2.14 - NMN nucleosidase

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ACTIVATING COMPOUND

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

ATP

Azotobacter vinelandii

-

less effective activator than GTP

171774

dGMP

Azotobacter vinelandii

-

-

171774

dGTP

Azotobacter vinelandii

-

-

171774

GDP

Azotobacter vinelandii

-

-

171774

GMP

Azotobacter vinelandii

-

-

171774

GTP

2 entries

guanosine 2'-monophosphate

Azotobacter vinelandii

-

-

171774

guanosine 3'-diphosphate-5'-triphosphate

Azotobacter vinelandii

-

guanine nucleotides, guanosinetriphosphate and polyphosphate derivatives, effective activation

171769

guanosine 3'-monophosphate

Azotobacter vinelandii

-

-

171774

guanosine 5'-tetraphosphate

Azotobacter vinelandii

-

most potent activator

171774

RNA

Azotobacter vinelandii

-

-

171769, 171770

SO42-

Azotobacter vinelandii

-

10 mM relative activity 103%, 100% activity with nicotinamide as substrate

171769

GTP

Azotobacter vinelandii

-

-

171770

GTP

Azotobacter vinelandii

-

most potent activator

171774