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3.2.1.51: alpha-L-fucosidase

This is an abbreviated version!
For detailed information about alpha-L-fucosidase, go to the full flat file.

Word Map on EC 3.2.1.51

Reaction

an alpha-L-fucoside
+
H2O
=
L-fucose
+
an alcohol

Synonyms

acid hydrolase, Afc2, Afc3, AFU, Alf1_Wf, alfA, alfB, alfC, alpha-fuc, alpha-fucosidase, alpha-L fucosidase, alpha-L-fucosidase, alpha-L-fucosidase 1, alpha-L-fucosidase 2, alpha-L-fucosidase I, alpha-L-fucosidase iso2, alpha-L-fucosidase isoenzyme 1, Alpha-L-fucoside fucohydrolase, alpha-L-fucoside fucohydrolase 2, alphafuc, bfo_2737, BgFUC, Eo0918, Eo3066, Eo3812, FpFucA, FucA, Fuca1, Fuca2, Fuca3, FucFA, fucosidase, alpha-L-1, tissue, h-Fuc, mfuc1, mfuc2, mfuc3, mfuc4, mfuc5, mfuc6, mfuc7, Pap-Alf, serum AFU, serum alpha-L-fucosidase, TfFuc1, TMalphafuc

ECTree

     3 Hydrolases
         3.2 Glycosylases
             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
                3.2.1.51 alpha-L-fucosidase

Substrates Products

Substrates Products on EC 3.2.1.51 - alpha-L-fucosidase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2'-fucosyllactitol + H2O
alpha-L-fucose + lactitol
show the reaction diagram
2'-fucosyllactose + H2O
alpha-L-fucose + lactose
show the reaction diagram
-
-
-
?
2-chloro-4-nitrophenyl alpha-L-fucopyranoside + H2O
2-chloro-4-nitrophenol + L-fucose
show the reaction diagram
pH 6.8, 37°C
-
-
?
2-deoxy-2-fluoro-alpha-L-fucosyl fluoride + H2O
fluoride + 2-deoxy-2-fluoro-alpha-L-fucose
show the reaction diagram
-
-
-
?
2-fluoro-4-nitrophenyl alpha-L-fucopyranoside + H2O
2-fluoro-4-nitrophenol + L-fucose
show the reaction diagram
pH 6.8, 37°C
-
-
?
2-methyl-4-nitrophenyl alpha-L-fucopyranoside + H2O
2-methyl-4-nitrophenol + L-fucose
show the reaction diagram
pH 6.8, 37°C
-
-
?
2-nitrophenyl alpha-L-fucopyranoside + H2O
2-nitrophenol + alpha-L-fucopyranose
show the reaction diagram
-
-
-
-
?
2alpha-fucosyl-lactitol + H2O
?
show the reaction diagram
-
-
-
-
?
3'-fucosyllactose + H2O
alpha-L-fucose + ?
show the reaction diagram
3-fucosyllactitol + H2O
alpha-L-fucose + lactitol
show the reaction diagram
3-fucosyllactose + H2O
L-fucose +
show the reaction diagram
3-fucosyllactose + H2O
L-fucose + ?
show the reaction diagram
-
cleavage of alpha-1,3 bond
-
-
?
4-methylumbelliferyl alpha-L-fucopyranoside
4-methylumbelliferone + alpha-L-fucose
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl alpha-L-fucopyranoside + H2O
4-methylumbelliferone + alpha-L-fucopyranose
show the reaction diagram
4-methylumbelliferyl alpha-L-fucopyranoside + H2O
4-methylumbelliferone + alpha-L-fucose
show the reaction diagram
4-methylumbelliferyl-alpha-L-fucopyranoside + H2O
4-methylumbelliferone + alpha-L-fucose
show the reaction diagram
4-methylumbelliferyl-alpha-L-fucopyranoside + H2O
methylumbelliferone + alpha-L-fucose
show the reaction diagram
-
-
-
-
?
4-methylumbelliferyl-beta-fucoside
?
show the reaction diagram
-
-
-
-
?
4-nitrophenyl 2-sulfo-alpha-L-fucopyranoside + H2O
4-nitrophenol + 2-sulfo-alpha-L-fucopyranose
show the reaction diagram
-
hydrolysis at 1.9% compared to 4-nitrophenyl-alpha-L-fucopyranoside
-
-
?
4-nitrophenyl alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-beta-D-Glc + H2O
alpha-L-fucose + 4-nitrophenyl beta-D-Gal-(1->4)-beta-D-Glc
show the reaction diagram
-
hydrolysis at 1.6% compared to 4-nitrophenyl-alpha-L-fucopyranoside
-
-
?
4-nitrophenyl alpha-L-Fuc-(1->3)-beta-D-Gal-(1->4)-beta-D-Glc + H2O
alpha-L-fucose + 4-nitrophenyl beta-D-Gal-(1->4)-beta-D-Glc
show the reaction diagram
4-nitrophenyl alpha-L-fucopyranoside + H2O
4-nitrophenol + alpha-L-fucopyranose
show the reaction diagram
4-nitrophenyl alpha-L-fucopyranoside + H2O
4-nitrophenol + L-fucose
show the reaction diagram
sodium acetate buffer 50 mM, pH 5.0, 37°C
-
-
?
4-nitrophenyl alpha-L-fucoside + H2O
4-nitrophenol + alpha-L-fucose
show the reaction diagram
-
-
-
?
4-nitrophenyl-alpha-L-fucopyranoside
?
show the reaction diagram
-
assay at pH 4.5, 37°C for 3 h, reaction stopped by addition of borate buffer
-
-
?
4-nitrophenyl-alpha-L-fucopyranoside + H2O
4-nitrophenol + alpha-L-fucopyranose
show the reaction diagram
4-nitrophenyl-alpha-L-fucopyranoside + H2O
4-nitrophenol + alpha-L-fucose
show the reaction diagram
4-nitrophenyl-alpha-L-fucopyranoside + H2O
4-nitrophenol + L-fucose
show the reaction diagram
4-nitrophenyl-alpha-L-fucopyranoside + N-acetyl-D-glucosamine + H2O
4-nitrophenol + alpha-L-Fuc-(1-3)-D-GlcNAc
show the reaction diagram
4-nitrophenyl-alpha-L-fucopyranoside + N-acetyl-D-glucosamine + H2O
4-nitrophenol + alpha-L-fucose-(1-3)-D-GlcNAc
show the reaction diagram
-
catalytic residues Asp242, Glu58, and Glu292
-
-
?
4-nitrophenyl-alpha-L-fucoside + H2O
4-nitrophenol + alpha-L-fucose
show the reaction diagram
4-nitrophenyl-alpha-L-fucoside + H2O
alpha-L-fucopyranose + 4-nitrophenol
show the reaction diagram
-
-
-
-
?
6-O-alpha-L-Fuc-N,N'-diacetylchitobiose + H2O
alpha-L-fucose + N,N'-diacetylchitobiose
show the reaction diagram
-
-
-
?
6-O-alpha-L-fucopyranosyl-N-acetylglucosamine + H2O
alpha-L-fucopyranose + N-acetyl-glucosamine
show the reaction diagram
-
Fuc-alpha-1,6-GlcNAc-linkage most susceptible
-
?
alpha-L-Fuc-(1-2)-beta-D-Gal-(1-3)-D-GalNAc + H2O
alpha-L-fucose + beta-D-Gal-(1-3)-D-GalNAc
show the reaction diagram
alpha-L-Fuc-(1-2)-beta-D-Gal-(1-4)-beta-D-GlcNAc-1-Me + H2O
alpha-L-fucose + beta-D-Gal-(1-4)-beta-D-GlcNAc-1-Me
show the reaction diagram
alpha-L-Fuc-(1-2)-D-Gal + N-acetyl-D-glucosamine
alpha-L-Fuc-(1-3)-D-GlcNAc + D-galactose
show the reaction diagram
-
same yield of transglycosylation and hydrolysis products
-
?
alpha-L-Fuc-(1-3)-a-L-Fuc-O-4-NP + H2O
?
show the reaction diagram
-
-
-
-
?
alpha-L-Fuc-(1-3)-alpha-L-Fuc-O-4-nitrophenyl ester + H2O
?
show the reaction diagram
-
-
-
-
?
alpha-L-Fuc-(1-3)-D-Gal + N-acetyl-D-glucosamine
alpha-L-Fuc-(1-3)-D-GlcNAc + D-galactose
show the reaction diagram
-
slower hydrolysis than for the alpha-(1-6)- or alpha-(1-2)-isomers, transglycosylation activity
-
?
alpha-L-Fuc-(1-3)-D-GlcNAc + H2O
alpha-L-fucose + N-acetyl-D-glucosamine
show the reaction diagram
-
-
-
-
?
alpha-L-Fuc-(1-4)-D-GlcNAc + H2O
alpha-L-fucose + N-acetyl-D-glucosamine
show the reaction diagram
-
-
-
-
?
alpha-L-Fuc-(1-6)-D-Gal + N-acetyl-D-glucosamine
alpha-L-Fuc-(1-6)-D-GlcNAc + D-galactose
show the reaction diagram
-
same yield of transglycosylation and hydrolysis products
-
?
alpha-L-Fuc-(1-6)-D-GlcNAc + H2O
alpha-L-fucose + N-acetyl-D-glucosamine
show the reaction diagram
-
-
-
-
?
alpha-L-Fuc-(1->2)-beta-D-Gal-(1->4)-beta-D-GlcNAc-OMe + H2O
alpha-L-fucose + beta-D-Gal-(1->4)-beta-D-GlcNAc-OMe
show the reaction diagram
-
-
-
?
alpha-L-Fuc-(1->4)-GlcNAc-poly-acrylamide polymer + H2O
alpha-L-fucose + GlcNAc-poly-acrylamide polymer
show the reaction diagram
-
-
-
?
alpha-L-fucopyranosyl fluoride + methyl 2-(acetylamino)-2-deoxy-alpha-D-glucopyranoside
methyl 2-(acetylamino)-2-deoxy-3-O-(6-deoxy-alpha-L-galactopyranosyl)-alpha-D-glucopyranoside + fluoride
show the reaction diagram
-
-
13% yield based on the donor substrate
-
?
alpha-L-fucopyranosyl fluoride + N-acetylglucosamine
2-(acetylamino)-2-deoxy-3-O-(6-deoxy-alpha-L-galactopyranosyl)-alpha-D-glucopyranose + fluoride
show the reaction diagram
-
-
7% yield based on the donor substrate
-
?
alpha-L-fucopyranosyl fluoride + prop-2-en-1-yl 2-(acetylamino)-2-deoxy-alpha-D-glucopyranoside
prop-2-en-1-yl 2-(acetylamino)-2-deoxy-3-O-(6-deoxy-alpha-L-galactopyranosyl)-alpha-D-glucopyranoside + fluoride
show the reaction diagram
-
-
8% yield based on the donor substrate
-
?
alpha-L-fucopyranosyl fluoride + prop-2-en-1-yl 2-(acetylamino)-2-deoxy-beta-D-glucopyranoside
prop-2-en-1-yl 2-(acetylamino)-2-deoxy-3-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-glucopyranoside + fluoride
show the reaction diagram
-
-
34% yield based on the donor substrate
-
?
alpha-L-fucopyranosyl-(1->2)-beta-D-galactopyranosyl-(1->4)-2-acetamido-2-deoxy-D-galactitol + H2O
alpha-L-fucose + beta-D-galactopyranosyl-(1->4)-2-acetamido-2-deoxy-D-galactitol
show the reaction diagram
-
-
-
?
alpha-L-fucopyranosyl-(1->2)-D-galactopyranose + H2O
alpha-L-fucose + D-galactose
show the reaction diagram
the enzyme does not hydrolyze other fucosyloligosaccharides or 4-nitrophenyl-alpha-L-fucoside
-
-
?
alpha-L-fucosyl fluoride + H2O
alpha-L-fucose + fluoride
show the reaction diagram
alpha-L-fucosyl fluoride + H2O
fluoride + alpha-L-fucose
show the reaction diagram
-
-
-
?
antigen H disaccharide + H2O
?
show the reaction diagram
-
-
-
-
?
antigen H type II trisaccharide + H2O
?
show the reaction diagram
-
-
-
-
?
beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-D-GlcNAc + H2O
alpha-L-fucose + beta-D-Gal-(1-3)-D-GlcNAc
show the reaction diagram
slightly hydrolyzed, since fucose monosaccharide is detected after the reaction
-
-
?
beta-D-Gal-(1->3)-[alpha-L-Fuc-(1->4)]-D-GlcNAc + H2O
alpha-L-fucose + beta-D-Gal-(1->3)-D-GlcNAc
show the reaction diagram
i.e. Le(x) trisaccharide
-
-
?
beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-beta-D-GlcNAc-OMe + H2O
?
show the reaction diagram
-
-
-
?
beta-D-Gal-(1->4)-[alpha-L-Fuc-(1->3)]-D-GlcNAc + H2O
alpha-L-fucose + beta-D-Gal-(1->4)-D-GlcNAc
show the reaction diagram
i.e. Le(a) trisaccharide
-
-
?
beta-D-GlcNAc-(1-4)-(alpha-L-Fuc-(1-6))-D-GlcNAc + H2O
alpha-L-fucose + beta-D-GlcNAc-(1-4)-D-GlcNAc
show the reaction diagram
Fuc-alpha-(1-2)-Fuc-beta-4-nitrophenol + H2O
alpha-L-fucose + Fuc-beta-4-nitrophenol
show the reaction diagram
-
-
-
?
Fuc-alpha-(1-2)-Gal + H2O
alpha-L-fucose + D-galactose
show the reaction diagram
Fuc-alpha-(1-2)-Gal-beta-(1-3)-GalNAc-alpha-phenol + H2O
alpha-L-fucose + Gal-beta-(1-3)-N-acetyl-galactosaminyl-phenol
show the reaction diagram
-
-
-
?
Fuc-alpha-(1-2)-Gal-beta-(1-3)-GlcNAc-beta-(1-3)-Gal-beta-(1-4)-Glc + H2O
alpha-L-fucose + Gal-beta-(1-3)-GlcNAc-beta-(1-3)-Gal-beta-(1-4)-Glc
show the reaction diagram
Fuc-alpha-(1-2)-Gal-beta-(1-3)-GlcNAc-beta-(1-4)-Glc + H2O
Gal-beta-(1-3)-GlcNAc-beta-(1-4)-Glc + alpha-L-fucose
show the reaction diagram
Fuc-alpha-(1-2)-Gal-beta-(1-3)-[Fuc-alpha-(1-4)]-GlcNAc-beta-(1-3)-Gal-beta-(1-4)-Glc + H2O
Gal-beta-(1-3)-[Fuc-alpha-(1-4)]-GlcNAc-beta-(1-3)-Gal-beta-(1-4)-Glc + alpha-L-fucose
show the reaction diagram
-
lacto-N-difucohexaitol I, NaBH4-reduced oligosaccharide
-
?
Fuc-alpha-(1-2)-Gal-beta-(1-4)-Glc + H2O
alpha-L-fucose + lactose
show the reaction diagram
Fuc-alpha-(1-2)-Gal-beta-(1-4)-sorbitol + H2O
alpha-L-fucose + Gal-beta-(1-4)-sorbitol
show the reaction diagram
Fuc-alpha-(1-2)-Gal-beta-(1-4)-[Fuc-alpha-(1-3)]-GlcNAc-beta-(1-3)-Gal-beta-(1-4)-Glc + H2O
Gal-beta-(1-4)-[Fuc-alpha-(1-3)]-GlcNAc-beta-(1-3)-Gal-beta-(1-4)-Glc + alpha-L-fucose
show the reaction diagram
Fuc-alpha-(1-2)-Gal-beta-4-nitrophenol + H2O
alpha-L-fucose + beta-galactosyl-4-nitrophenol
show the reaction diagram
-
-
-
?
Fuc-alpha-(1-2)-Glc + H2O
alpha-L-fucose + D-glucose
show the reaction diagram
-
-
-
?
Fuc-alpha-(1-2)-Xyl + H2O
alpha-L-fucose + D-xylose
show the reaction diagram
-
-
-
?
Fuc-alpha-(1-2)-[Gal-alpha-(1-3)]-Gal-beta-phenol + H2O
alpha-L-fucose + Gal-alpha-(1-3)-Gal-beta-phenol
show the reaction diagram
-
-
-
?
Fuc-alpha-(1-3)-Gal + H2O
alpha-L-fucose + D-galactose
show the reaction diagram
-
-
-
?
Fuc-alpha-(1-3)-Gal-beta-(1-4)-Glc + H2O
alpha-D-fucose + lactose
show the reaction diagram
Fuc-alpha-(1-3)-Gal-beta-(1-4)-Glc + H2O
alpha-L-fucose + lactose
show the reaction diagram
Fuc-alpha-(1-3)-Glc + H2O
alpha-L-fucose + D-glucose
show the reaction diagram
-
-
-
?
Fuc-alpha-(1-3)-GlcNAc + H2O
alpha-L-fucose + N-acetyl-D-glucosamine
show the reaction diagram
Fuc-alpha-(1-3)-GlcNAc-beta-O(CH2)6NHCOCF3 + H2O
alpha-L-fucose + GlcNAc-beta-O(CH2)6NHCOCF3
show the reaction diagram
-
-
-
?
Fuc-alpha-(1-3)-GlcNAc-beta-phenol + H2O
alpha-L-fucose + N-acetyl-glucosaminyl-beta-phenol
show the reaction diagram
-
-
-
?
Fuc-alpha-(1-3)-GlcNAc-phenol + H2O
alpha-L-fucose + N-acetyl-glucosaminyl-beta-phenol
show the reaction diagram
-
-
-
-
?
Fuc-alpha-(1-4)-GlcNAc + H2O
alpha-L-fucose + N-acetyl-D-glucosamine
show the reaction diagram
-
-
-
?
Fuc-alpha-(1-4)-GlcNAc-beta-phenol + H2O
alpha-L-fucose + beta-N-acetyl-glucosaminyl-phenol
show the reaction diagram
-
-
-
?
Fuc-alpha-(1-4)-[Gal-beta-(1-3)]-GlcNAc-beta-phenol + H2O
alpha-L-fucose + Gal-beta-(1-3)-GlcNAc-beta-phenol
show the reaction diagram
-
-
-
?
Fuc-alpha-(1-6)-Gal + H2O
alpha-L-fucose + D-galactose
show the reaction diagram
-
-
-
?
Fuc-alpha-(1-6)-GlcNAc + H2O
alpha-L-fucose + N-acetyl-D-glucosamine
show the reaction diagram
Fuc-alpha-(1-6)-GlcNAc-4-nitrophenol + H2O
alpha-L-fucose + GlcNAc-4-nitrophenol
show the reaction diagram
-
-
-
?
Fuc-alpha-(1-6)-GlcNAc-beta-Asn + H2O
alpha-L-fucose + N-acetyl-D-glucosaminyl-Asn
show the reaction diagram
-
-
-
?
Fuc-alpha-(1-6)-[Gal-beta-(1-3)]-GlcNAc-beta-OCH3 + H2O
alpha-L-fucose + Gal-beta-(1-3)-GlcNAc-beta-OCH3
show the reaction diagram
-
-
-
?
Fuc-alpha-(1->2)-Gal-beta-(1->3)-[Fuc-alpha-(1->6)]GlcNAc-beta-(1->3)-Gal-beta-(1->4)GlcNAc + H2O
alpha-L-fucose + Gal-beta-(1->3)-[Fuc-alpha-(1->6)]GlcNAc-beta-(1->3)-Gal-beta-(1->4)GlcNAc
show the reaction diagram
-
low activity
-
?
Fuc-alpha-(1->2)-Gal-beta-(1->3)-[Fuc-alpha-(1->6)]GlcNAc-beta-(1->3)-Gal-beta-(1->4)GlcNAc + H2O + H2O
alpha-L-fucose + Fuc-alpha-(1->2)-Gal-beta-(1->3)-GlcNAc-beta-(1->3)-Gal-beta-(1->4)GlcNAc + H2O
show the reaction diagram
Bacillus fulminans
-
-
-
?
fucoidan + H2O
alpha-L-fucose + ?
show the reaction diagram
fucose residues from fucose-containing oligosaccharide chains on porcine gastric mucin + H2O
?
show the reaction diagram
Gal-beta-(1-3)-GlcNAc-beta-(1-3)-[Fuc-alpha-(1-4)]-Gal-beta-(1-4)-Glc + H2O
alpha-L-fucose + Gal-beta-(1-3)-GlcNAc-beta-(1-3)-Gal-beta-(1-4)-Glc
show the reaction diagram
Gal-beta-(1-4)-GlcNAc-[Fuc-alpha-(1-4)]-beta-(1-3)-Gal-beta-(1-4)-Glc + H2O
alpha-L-fucose + Gal-beta-(1-4)-GlcNAc-beta-(1-3)-Gal-beta-(1-4)-Glc
show the reaction diagram
Gal-beta-(1-4)[Fuc-alpha-(1-3)]-Glc + H2O
Gal-beta-(1-4)-Glc + alpha-L-fucose
show the reaction diagram
GalNAc-alpha-(1-3)-Gal-[Fuc-alpha-(1-2)] + H2O
alpha-L-fucose + GalNAc-alpha-(1-3)-Gal
show the reaction diagram
gastric mucin + H2O
alpha-L-fucose + ?
show the reaction diagram
GlcNAc-beta-(1-2)-Man-alpha-(1-6)-[GlcNAc-beta-(1-2)-Man-alpha-(1-3)]-[Xyl-beta-(1-2)]-Man-beta-(1-4)-GlcNAc-beta-(1-4)-[Fuc-alpha-(1-3)]-GlcNAc-pyridylaminoside + H2O
alpha-L-fucose + [GlcNAc-beta-(1-2)-Man-alpha-(1-6)]-[GlcNAc-beta-(1-2)-Man-alpha-(1-3)]-[Xyl-beta-(1-2)]-Man-beta-(1-4)-GlcNAc-beta-(1-4)-GlcNAc-pyridylaminoside
show the reaction diagram
-
not completely hydrolysed due to steric hinderance by beta-(1-2)-GlcNAc residues
-
?
glycopeptide + H2O
alpha-L-fucose + ?
show the reaction diagram
glycopeptide from desialyzed porcine submaxillary mucin + H2O
alpha-L-fucose + ?
show the reaction diagram
Bacillus fulminans
-
-
-
-
?
glycoprotein + H2O
alpha-L-fucose + ?
show the reaction diagram
glycosphingolipid + H2O
alpha-L-fucose + ?
show the reaction diagram
-
blood-group active types B and H
-
?
gp120 oligosaccharide + H2O
alpha-L-fucose + ?
show the reaction diagram
-
-
-
-
?
gp120 oligosaccharides + H2O
alpha-L-fucose + ?
show the reaction diagram
-
released from recombinant CHO cell-produced gp120, glycoproteins containing fucose in alpha-1,3- and alpha-1,6-linkages are no substrates
-
?
IgG Fc peptide + H2O
alpha-L-fucose + ?
show the reaction diagram
IgG L peptide + H2O
alpha-L-fucose + ?
show the reaction diagram
-
-
-
?
lacto-N-difucohexaose I + H2O
L-fucose + ?
show the reaction diagram
-
cleavage of alpha-1,4 bond
-
-
?
lacto-N-difucohexaose II + H2O
L-fucose + ?
show the reaction diagram
-
cleavage of alpha-1,4 bond
-
-
?
lacto-N-fucopentaitol II + H2O
alpha-L-fucose + ?
show the reaction diagram
-
-
-
-
?
lacto-N-fucopentaitol III + H2O
alpha-L-fucose + ?
show the reaction diagram
lacto-N-fucopentaose + H2O
L-fucose +
show the reaction diagram
lacto-N-fucopentaose II + H2O
alpha-L-fucose + Gal-beta-(1-3)-GlcNAc-beta-(1-3)-Gal-beta-(1-4)-Glc
show the reaction diagram
lactoferrin + H2O
alpha-L-fucose + ?
show the reaction diagram
-
low activity
-
?
LH-beta peptic glycopeptide + H2O
alpha-L-fucose + ?
show the reaction diagram
-
-
-
?
m-nitrophenyl alpha-L-fucopyranoside + H2O
m-nitrophenol + L-fucose
show the reaction diagram
pH 6.8, 37°C
-
-
?
Man-beta-(1-6)-[Man-alpha-(1-3)-Xyl-beta-(1-2)]-Man-beta-(1-4)-GlcNAc-beta-(1-4)-[Fuc-alpha-(1-3)]-GlcNAc-pyridylaminoside + H2O
alpha-L-fucose + Man-beta-(1-6)-[Man-alpha-(1-3)-Xyl-beta-(1-2)]-Man-beta-(1-4)-GlcNAc-beta-(1-4)-GlcNAc-pyridylaminoside
show the reaction diagram
-
-
-
?
meconium H-1 + H2O
alpha-L-fucose + ?
show the reaction diagram
Bacillus fulminans
-
-
-
?
meconium H-2 + H2O
alpha-L-fucose + ?
show the reaction diagram
Bacillus fulminans
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?
meconium X-1 + H2O
alpha-L-fucose + ?
show the reaction diagram
Bacillus fulminans
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low activity
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?
methyl alpha-L-fucopyranoside + H2O
methanol + alpha-L-fucose
show the reaction diagram
milk + H2O
alpha-L-fucose + ?
show the reaction diagram
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human
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?
mono-sialylated-galactosylated biantennary N-glycan-core-substituted with alpha-(1->6)-linked fucose + H2O
L-fucose + ?
show the reaction diagram
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?
oligosaccharide + H2O
alpha-L-fucose + ?
show the reaction diagram
oligosaccharides + H2O
alpha-L-fucose + ?
show the reaction diagram
orosomucoid + H2O
alpha-L-fucose + ?
show the reaction diagram
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low activity, higher activity if desialyzed
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?
p-cyanophenyl alpha-L-fucopyranoside + H2O
p-cyanophenol + L-fucose
show the reaction diagram
pH 6.8, 37°C
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?
p-nitrophenyl alpha-L-fucopyranoside + H2O
p-nitrophenol + alpha-L-fucopyranose
show the reaction diagram
p-nitrophenyl alpha-L-fucopyranoside + methyl 2-(acetylamino)-2-deoxy-alpha-D-glucopyranoside
methyl 2-(acetylamino)-2-deoxy-3-O-(6-deoxy-alpha-L-galactopyranosyl)-alpha-D-glucopyranoside + p-nitrophenol
show the reaction diagram
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29% yield based on the donor substrate
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?
p-nitrophenyl alpha-L-fucopyranoside + prop-2-en-1-yl 2-(acetylamino)-2-deoxy-alpha-D-glucopyranoside
prop-2-en-1-yl 2-(acetylamino)-2-deoxy-3-O-(6-deoxy-alpha-L-galactopyranosyl)-alpha-D-glucopyranoside + p-nitrophenol
show the reaction diagram
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34% yield based on the donor substrate
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?
p-nitrophenyl alpha-L-fucopyranoside + prop-2-en-1-yl 2-(acetylamino)-2-deoxy-beta-D-glucopyranoside
prop-2-en-1-yl 2-(acetylamino)-2-deoxy-3-O-(6-deoxy-alpha-L-galactopyranosyl)-beta-D-glucopyranoside + p-nitrophenol
show the reaction diagram
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25% yield based on the donor substrate
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?
p-nitrophenyl alpha-L-fucoside + H2O
p-nitrophenol + alpha-L-fucose
show the reaction diagram
p-nitrophenyl-alpha-L-fucopyranoside + H2O
p-nitrophenol + alpha-L-fucose
show the reaction diagram
p-nitrophenyl-alpha-L-fucoside + H2O
L-fucose + p-nitrophenol
show the reaction diagram
the enzyme has low transglycosylation properties
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?
phenyl alpha-L-fucopyranoside + H2O
phenol + L-fucose
show the reaction diagram
pH 6.8, 37°C
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?
porcine submaxillary mucine, desialyzed + H2O
alpha-L-fucose + ?
show the reaction diagram
Bacillus fulminans
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?
propyl alpha-L-fucopyranoside + H2O
propanol + alpha-L-fucopyranose
show the reaction diagram
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-
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?
propyl alpha-L-fucopyranosyl-(1->2)-alpha-L-fucopyranoside + H2O
?
show the reaction diagram
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?
propyl alpha-L-fucopyranosyl-(1->3)-alpha-L-fucopyranoside + H2O
?
show the reaction diagram
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?
propyl alpha-L-fucopyranosyl-(1->4)-alpha-L-fucopyranoside + H2O
?
show the reaction diagram
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?
saliva + H2O
alpha-L-fucose + ?
show the reaction diagram
stomach + H2O
alpha-L-fucose + ?
show the reaction diagram
Bacillus fulminans
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?
submaxilary mucin trisaccharide + H2O
alpha-L-fucose + disaccharide
show the reaction diagram
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?
submaxillary mucin + H2O
alpha-L-fucose + ?
show the reaction diagram
thyroglobulin + H2O
alpha-L-fucose + ?
show the reaction diagram
Xyl-beta-(1-2)-Man-beta-(1-4)-GlcNAc-beta-(1-4)-[Fuc-alpha-(1-3)]-GlcNAc-pyridylaminoside + H2O
alpha-L-fucose + Xyl-beta-(1-2)-Man-beta-(1-4)-GlcNAc-beta-pyridylaminoside
show the reaction diagram
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?
Xylalpha(1-6)Glcbeta(1-4)[Xylalpha(1-6)]Glcbeta(1-4)[Fucalpha(1-2)Galbeta(1-2)Xylalpha(1-6)]Glcbeta(1-4)Glc + H2O
Xylalpha(1-6)Glcbeta(1-4)[Xylalpha(1-6)]Glcbeta(1-4)[Galbeta(1-2)Xylalpha(1-6)]Glcbeta(1-4)Glc + alpha-L-fucose
show the reaction diagram
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?
[Man-alpha-(1->6)]-[Man-alpha-(1->3)]-Man-beta-(1->4)-GlcNAc-beta-(1->4)-[Fuc-alpha-(1->6)]GlcNAc + H2O
[Man-alpha-(1->6)]-[Man-alpha-(1->3)]-Man-beta-(1->4)-GlcNAc-beta-(1->4)-GlcNAc + alpha-L-fucose
show the reaction diagram
additional information
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