3.2.1.46: galactosylceramidase

This is an abbreviated version!
For detailed information about galactosylceramidase, go to the full flat file.

Word Map on EC 3.2.1.46

3.2.1.46

krabbe

leukodystrophy

lysosomal

globoid

twitcher

psychosine

demyelination

myelin

infantile

galactosylsphingosine

nerve

neurodegenerative

oligodendrocyte

hematopoietic

sphingolipids

spastic

arylsulfatase

saposins

metachromatic

medicine

presymptomatic

schwann

glycosphingolipids

sphingomyelinase

galactolipids

gaucher

gangliosidosis

prosaposin

later-onset

drug development

myelin-forming

late-infantile

gm1-gangliosidosis

glucosylceramidase

glucocerebrosidase

gm1-ganglioside

diagnostics

4-methylumbelliferyl

Reaction

Synonyms

beta-galactocerebrosidase, beta-galactosylceramidase, ceramidase, galacatosyl-, ceramide galactosidase, cerebroside beta-galactosidase, cerebroside galactosidase, galactoceramidase, galactocerebrosidase, galactocerebroside beta-galactosidase, galactocerebroside galactosidase, galactocerebroside-beta-D-galactosidase, Galactosylceramidase, galactosylceramidase I, galactosylceramide beta-galactosidase, galactosylcerebrosidase, GALC, galcerase, GM1 ganglioside beta-galactosidase, lactosylceramidase, lactosylceramidase I

ECTree

3 Hydrolases

3.2 Glycosylases

3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds

3.2.1.46 galactosylceramidase

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Results	in table
15	Activating Compound
2042	AA Sequence
23	Application
1	CAS Registry Number
9	Cloned(Commentary)
1	Crystallization (Commentary)
1040	Disease/ Diagnostics
8	General Information
2	General Stability
22	Inhibitors
15	KM Value [mM]
9	Localization
1	Metals/Ions
19	Molecular Weight [Da]
25	Natural Substrates/ Products (Substrates)
39	Organism
2	Pathway
15	PDB ID
15	pH Optimum
5	pH Range
1	Posttranslational Modification
9	Protein Variants
11	Purification (Commentary)
1	Reaction
5	Reaction Type
38	Reference
55	Source Tissue
20	Specific Activity [micromol/min/mg]
99	Substrates and Products (Substrate)
4	Subunits
29	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
4	Temperature Stability [°C]

Inhibitors

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Inhibitors on EC 3.2.1.46 - galactosylceramidase

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2-hydroxydecanoyl DL-erythro-3-phenyl-2-amino-1,3-propanediol

Rattus norvegicus

2-hydroxy fatty acid amides of phenylaminopropanediol, noncompetitive

171513

2-hydroxydodecanoyl DL-erythro-3-phenyl-2-amino-1,3-propanediol

Rattus norvegicus

2-hydroxy fatty acid amide of phenylaminopropanediol, noncompetitive

171513

2-hydroxyhexadecanoyl DL-erythro-3-phenyl-2-amino-1,3-propanediol

Rattus norvegicus

2-hydroxy fatty acid amides of phenylaminopropanediol, noncompetitive

171513

2-hydroxyoctadecanoyl DL-erythro-3-phenyl-2-amino-1,3-propanediol

Rattus norvegicus

2-hydroxy fatty acid amides of phenylaminopropanediol, noncompetitive

171513

2-hydroxytetradecanoyl DL-erythro-3-phenyl-2-amino-1,3-propanediol

Rattus norvegicus

2-hydroxy fatty acid amides of phenylaminopropanediol, noncompetitive

171513

6-hexadecanoylamino-4-methylbelliferyl-beta-D-galactopyranoside

D-galactose

galactonolactone

galactonyl hydrazide

lactose

lactosyl ceramide

N-(6-aminohexyl)-D-galactonamide

Homo sapiens

171516

N-decanoyl psychosine

Rattus norvegicus

competitve and noncompetitive

171513

N-dodecanoyl psychosine

Rattus norvegicus

competitve and noncompetitive

171513

N-ethyl psychosine

Rattus norvegicus

competitve and noncompetitive

171513

N-hexyl psychosine

Rattus norvegicus

competitve and noncompetitive

171513

N-octanoyl psychosine

Rattus norvegicus

competitve and noncompetitive

171513

taurocholate

2 entries