3.2.1.45: glucosylceramidase

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For detailed information about glucosylceramidase, go to the full flat file.

Word Map on EC 3.2.1.45

3.2.1.45

gaucher

parkinsonism

spleen

marrow

gcase

neuronopathic

chitotriosidase

saposins

visceral

hematological

jewish

non-neuronopathic

sphingolipids

ashkenazi

thrombocytopenia

glycolipids

dementia

splenectomy

anemia

platelet

splenomegaly

hepatosplenomegaly

glycosphingolipids

autophagy-lysosomal

non-motor

corneum

synucleinopathies

genzyme

conduritol

organomegaly

alpha-synuclein

ambroxol

medicine

hepatomegaly

fabry

splenectomized

iminosugars

krabbe

taurocholate

niemann-pick

stratum

prosaposin

biotechnology

non-jewish

sphingomyelinase

atp13a2

deoxynojirimycin

hypersplenism

fetalis

cytopenia

reticuloendothelial

4-methylumbelliferyl

Reaction

Synonyms

ABG, acid beta-D-glucosidase, acid beta-glucocerebrosidase, acid beta-glucosidase, acid beta-glucosylceramidase, acid beta-glycosidase, acid glucosylceramidase, acid-beta-glucocerebrosidase, acid-beta-glucosidase, Alglucerase, beta-D-glucocerebrosidase, beta-GC, beta-glucocerebrosidase, beta-glucosidase, beta-glucosidase 2, beta-glucosylceramidase, beta-glucosylceramidase 2, beta-glycosylceramidase, bile acid beta-glucosidase, ceramidase, glucosyl-, ceramide glucosidase, cerebroside beta-glucosidase, Ceredase, Cerezyme, D-glucosyl-N-acylsphingosine glucohydrolase, GBA, GBA1, GBA2, Gcase, GCD, GCR, GDA, gene-activated human GlcCerase, Glc-Cerase, glcCer-beta-glucosidase, GlcCerase, glucocerebrosidase, glucocerebroside beta-glucosidase, glucose cerebrosidase, glucosphingosine glucosylhydrolase, glucosylceramidase, glucosylceramide beta-glucosidase, glucosylcerebrosidase, glucosylsphingosine beta-D-glucosidase, glucosylsphingosine beta-glucosidase, glycosylceramidase, glycosylceramide-beta-glucosidase, Imiglucerase, Klotho-related protein, KLrP, lysosomal glucosylceramidase, microsomal bile acid beta-glucosidase, N-acylsphingosyl-1-O-beta-D-glucoside:glucohydrolase, neutral beta-glycosylceramidase, neutral glucosylceramidase, NLGase, non-lysosomal beta-glucosylceramidase, non-lysosomal glucosylceramidase, nonlysosomal beta-glucosidase, nonlysosomal glucosylceramidase, psychosine hydrolase, taliglucerase alfa, velaglucerase alfa, Vpriv

ECTree

3 Hydrolases

3.2 Glycosylases

3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds

3.2.1.45 glucosylceramidase

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Results	in table
108	Activating Compound
6073	AA Sequence
31	Application
1	CAS Registry Number
40	Cloned(Commentary)
9	Crystallization (Commentary)
5372	Disease/ Diagnostics
14	General Information
11	General Stability
366	IC50 Value
434	Inhibitors
9	kcat/KM [mM/s]
70	Ki Value [mM]
65	KM Value [mM]
46	Localization
30	Molecular Weight [Da]
61	Natural Substrates/ Products (Substrates)
153	Organism
1	Oxidation Stability
3	Pathway
113	PDB ID
23	pH Optimum
7	pH Range
4	pH Stability
2	pI Value
9	Posttranslational Modification
169	Protein Variants
36	Purification (Commentary)
2	Reaction
1	Reaction Type
150	Reference
143	Source Tissue
30	Specific Activity [micromol/min/mg]
4	Storage Stability
214	Substrates and Products (Substrate)
14	Subunits
209	Synonyms
1	Systematic Name
11	Temperature Optimum [°C]
8	Temperature Stability [°C]
20	Turnover Number [1/s]

Synonyms

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Synonyms on EC 3.2.1.45 - glucosylceramidase

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ABG