3.2.1.36: hyaluronoglucuronidase
This is an abbreviated version!
For detailed information about hyaluronoglucuronidase, go to the full flat file.
Word Map on EC 3.2.1.36
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3.2.1.36
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hyaluronic
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glycosaminoglycans
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collagenase
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collagen
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venom
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chondroitin
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chondroitinase
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cartilage
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sperm
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proteoglycans
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testicular
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filler
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pain
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anesthesia
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phospholipase
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cumulus
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edema
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bupivacaine
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heparan
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alcian
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lidocaine
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cataract
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neuraminidase
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spermatozoa
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vitreous
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acrosomal
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pellucida
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hydrogel
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glycocalyx
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dermatan
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mucopolysaccharide
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akinesia
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ophthalmic
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pericellular
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pronase
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antivenoms
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acrosin
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myotoxicity
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aesthetic
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snakebite
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4-sulfate
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orbicularis
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vitreoretinal
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3hglucosamine
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heparitinase
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subconjunctival
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medicine
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eyelid
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phacoemulsification
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intralesional
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myxoid
- 3.2.1.36
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hyaluronic
- glycosaminoglycans
- collagenase
- collagen
- venom
- chondroitin
- chondroitinase
- cartilage
- sperm
- proteoglycans
- testicular
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filler
- pain
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anesthesia
- phospholipase
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cumulus
- edema
- bupivacaine
- heparan
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alcian
- lidocaine
- cataract
- neuraminidase
- spermatozoa
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vitreous
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acrosomal
- pellucida
- hydrogel
- glycocalyx
- dermatan
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mucopolysaccharide
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akinesia
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ophthalmic
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pericellular
- pronase
- antivenoms
- acrosin
- myotoxicity
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aesthetic
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snakebite
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4-sulfate
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orbicularis
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vitreoretinal
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3hglucosamine
- heparitinase
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subconjunctival
- medicine
- eyelid
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phacoemulsification
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intralesional
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myxoid
Reaction
Synonyms
glucuronoglucosaminoglucan hyaluronate lyase, HAase, HAase-B, hyaluronate lyase HylP2, hyaluronate lyase HylP3, hyaluronidase, HYase, LHase, orgelase, VesT2a, VesT2b
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Substrates Products
Substrates Products on EC 3.2.1.36 - hyaluronoglucuronidase
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REACTION DIAGRAM
dermatan sulfate + H2O
?
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chondroitin sulfate B, low activity
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-
?
hyaluronan + H2O
hyaluronan tetrasaccharides + hyaluronan hexasaccharides
hyaluronan is mainly degraded into hyaluronan tetrasaccharides and hyaluronan hexasaccharides. The proportion of hyaluronan tetrasaccharides and hyaluronan hexasaccharides is accurately controlled by amount of enzyme. Higher yield of hyaluronan tetrasaccharides is achieved with higher activity of the enzyme
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-
?
hyaluronic acid + H2O
(N-acetylglucosamine)-(glucuronic acid)-(N-acetylglucosamine)-(glucuronic acid) + ?
?
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39% activity compared to hyaluronan
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-
?
chondroitin sulfate A + H2O
?
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39% activity compared to hyaluronan
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-
?
chondroitin sulfate A + H2O
oligosaccharides + ?
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low activity
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-
?
?
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13.5% activity compared to hyaluronan
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-
?
chondroitin sulfate C + H2O
?
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13.5% activity compared to hyaluronan
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-
?
?
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37.1% activity compared to hyaluronan
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-
?
chondroitin sulfate D + H2O
?
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37.1% activity compared to hyaluronan
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-
?
N-acetyl-beta-D-glucosamine + D-glucuronate + ?
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-
-
-
?
hyaluronan + 2 H2O
N-acetyl-beta-D-glucosamine + D-glucuronate + ?
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-
-
-
?
(N-acetylglucosamine)-(glucuronic acid)-(N-acetylglucosamine)-(glucuronic acid) + ?
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-
-
-
?
hyaluronic acid + H2O
(N-acetylglucosamine)-(glucuronic acid)-(N-acetylglucosamine)-(glucuronic acid) + ?
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-
-
-
?
hyaluronic acid + H2O
(N-acetylglucosamine)-(glucuronic acid)-(N-acetylglucosamine)-(glucuronic acid) + ?
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-
-
-
?
hyaluronic acid + H2O
(N-acetylglucosamine)-(glucuronic acid)-(N-acetylglucosamine)-(glucuronic acid) + ?
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-
-
-
?
hyaluronic acid + H2O
(N-acetylglucosamine)-(glucuronic acid)-(N-acetylglucosamine)-(glucuronic acid) + ?
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-
-
-
?
hyaluronic acid + H2O
(N-acetylglucosamine)-(glucuronic acid)-(N-acetylglucosamine)-(glucuronic acid) + ?
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-
-
-
?
hyaluronic acid + H2O
?
Clostridium welchii
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further hydrolysis of the end-products from bovine testicular enzyme
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-
?
hyaluronic acid + H2O
?
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major pathogenic factor of serological group B streptococci
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-
?
hyaluronic acid + H2O
?
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further hydrolysis of the end-products from bovine testicular enzyme
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-
?
hyaluronic acid + H2O
hyaluronic acid oligomers
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-
-
?
?
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no activity with dermatan sulfate, heparin sodium, heparan sulfate, sodium alginate, chitosan, chitin, sodium carboxymethyl cellulose, dextran, carboxymethyl dextran, xanthan gum, gellan gum, soluble starch, carrageenan, Konjac glucomannan, synanthrin, gumacabic powder, glycogen, or pectin
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-
?
additional information
?
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no activity with dermatan sulfate, heparin sodium, heparan sulfate, sodium alginate, chitosan, chitin, sodium carboxymethyl cellulose, dextran, carboxymethyl dextran, xanthan gum, gellan gum, soluble starch, carrageenan, Konjac glucomannan, synanthrin, gumacabic powder, glycogen, or pectin
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-
?
additional information
?
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not: chondroitin, heparan sulfate, chondroitin sulfate
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-
?
additional information
?
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not: chondroitin, heparan sulfate, chondroitin sulfate
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-
?