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3.2.1.36: hyaluronoglucuronidase

This is an abbreviated version!
For detailed information about hyaluronoglucuronidase, go to the full flat file.

Word Map on EC 3.2.1.36

Reaction

hyaluronic acid hexasaccharide
+
H2O
=
GlcAbeta(1-3)GlcNAcbeta(1-4)GlcA
 +
GlcNAcbeta(1-4)GlcAbeta(1-3)GlcNAc

Synonyms

glucuronoglucosaminoglucan hyaluronate lyase, HAase, HAase-B, hyaluronate lyase HylP2, hyaluronate lyase HylP3, hyaluronidase, HYase, LHase, orgelase, VesT2a, VesT2b

ECTree

     3 Hydrolases
         3.2 Glycosylases
             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
                3.2.1.36 hyaluronoglucuronidase

Inhibitors

Inhibitors on EC 3.2.1.36 - hyaluronoglucuronidase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Al3+
-
strong inhibition at 10 mM
Butane-2,3-dione
-
-
deferoxamine mesylate
-
-
Mn2+
-
strong inhibition at 10 mM
Phenylglyoxal
-
-
polymer from gentisic acid
-
polymer from hydroxysulfonic acid
-
with formaldehyde, nearly complete inhibition at 0.01 mg/ml
-
SDS
-
complete inhibition at any concentrations
serum protein
-
from human, inhibition by a true antibody
-
Triton X-100
-
moderately inhibits enzyme activity by 3%-30% at different concentrations
Tween 80
-
moderately inhibits enzyme activity by 3%-30% at different concentrations