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3.2.1.31: beta-glucuronidase

This is an abbreviated version!
For detailed information about beta-glucuronidase, go to the full flat file.

Word Map on EC 3.2.1.31

Reaction

a beta-D-glucuronoside
+
H2O
=
D-glucuronate
 +
an alcohol

Synonyms

beta-D-glucuronidase, Beta-D-glucuronoside glucuronosohydrolase, Beta-G1, beta-Gluc, beta-glucuronidase, beta-glucuronidase A, betaG, BLG, exo-beta-D-glucuronidase, exo-beta-glucuronidase, GlcAase, glucuronidase, beta-glucuronide glucuronohydrolase, GUR, GUS, Gus2, GusA, GusB, hGUSB, ketodase, More, PGUS, TM1062, TmGUSI, UidA

ECTree

     3 Hydrolases
         3.2 Glycosylases
             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
                3.2.1.31 beta-glucuronidase

Natural Substrates Products

Natural Substrates Products on EC 3.2.1.31 - beta-glucuronidase

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NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
curcumin-beta-D-glucuronide + H2O
curcumin + beta-D-glucuronic acid
show the reaction diagram
curcumin, despite low systemic bioavailability, may be enzymatically activated (deconjugated) within GUSB-enriched bone to exert protective effects, a metabolic process that can also contribute to bone-protective effects of other highly glucuronidated dietary polyphenols
-
-
?
dermatan sulfate + H2O
?
show the reaction diagram
-
-
-
-
?
heparan sulfate + H2O
?
show the reaction diagram
-
-
-
-
?
luteolin triglucuronide + H2O
?
show the reaction diagram
-
-
-
-
?
oestrone 3-glucuronide + H2O
?
show the reaction diagram
-
-
-
-
?
retinyl-beta-glucuronide + H2O
retinol + D-glucuronide
show the reaction diagram
-
-
-
-
?
additional information
?
-