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3.2.1.31: beta-glucuronidase

This is an abbreviated version!
For detailed information about beta-glucuronidase, go to the full flat file.

Word Map on EC 3.2.1.31

Reaction

a beta-D-glucuronoside
+
H2O
=
D-glucuronate
+
an alcohol

Synonyms

beta-D-glucuronidase, Beta-D-glucuronoside glucuronosohydrolase, Beta-G1, beta-Gluc, beta-glucuronidase, beta-glucuronidase A, betaG, BLG, exo-beta-D-glucuronidase, exo-beta-glucuronidase, GlcAase, glucuronidase, beta-glucuronide glucuronohydrolase, GUR, GUS, Gus2, GusA, GusB, hGUSB, ketodase, More, PGUS, TM1062, TmGUSI, UidA

ECTree

     3 Hydrolases
         3.2 Glycosylases
             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
                3.2.1.31 beta-glucuronidase

IC50 Value

IC50 Value on EC 3.2.1.31 - beta-glucuronidase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.0009
1,1'-(3-methyl-4-phenylthieno[2,3-b]thiophene-2,5-diyl)bis(4,4,4-triethoxybut-2-en-1-one)
Homo sapiens
-
pH not specified in the publication, 37°C
7.5
D-glucuronate
Escherichia coli
-
IC50: 7.5 mM, competitive
0.0458
D-saccharic acid 1,4-lactone
Homo sapiens
-
pH not specified in the publication, 37°C
2.32
fucoxanthin
Escherichia coli
-
pH not specified in the publication, at 37°C
0.08
glycyrrhizin
Escherichia coli
-
IC50: 0.08 mM, competitive
0.09
NEM
Escherichia coli
-
IC50: 0.09 mM
0.04
p-chloromercuriphenylsulfonic acid
Escherichia coli
-
IC50: 0.04 mM
0.3
p-nitrophenol
Escherichia coli
-
IC50: 0.3 mM, competitive
0.09
saccharic acid 1,4-lactone
Escherichia coli
-
IC50: 0.09 mM, competitive
1
silybin
Escherichia coli
-
IC50: 1 mM, non-competitive
0.3
TLCK
Escherichia coli
-
IC50: 0.3 mM