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3.2.1.3: glucan 1,4-alpha-glucosidase

This is an abbreviated version!
For detailed information about glucan 1,4-alpha-glucosidase, go to the full flat file.

Word Map on EC 3.2.1.3

Reaction

(alpha-D-glucopyranosyl-(1-4))n-alpha-D-glucopyranose
+
H2O
=
(alpha-D-glucopyranosyl-(1-4))n-1-alpha-D-glucopyranose
+
beta-D-glucopyranose

Synonyms

1,4-alpha-D-glucan glucohydrolase, 1,4-alpha-D-glucan-glucohydrolase, acid maltase, alpha-(1,4)-D-glucan glucohydrolase, alpha-1,4-D-glucan glucohydrolase, alpha-1,4-glucan glucohydrolase, AMG, AmyA, AmyC, AmyD, amyloglucosidase, AnGA, APGA1, AtriGA15A, exo-1,4-alpha-D-glucan glucanohydrolase, exo-1,4-alpha-D-glucanohydrolase, exo-1,4-alpha-glucosidase, exo-amylase, GA, GA A, GA1, GA2, GAI, GAII, GAM, GAM-1, GAM-2, gamma-amylase, GAMP, GHF15 glucoamylase, GLA, Gla1, GlaA, GLL1, Glu-1.1, Glu-A, Glu1, GlucaM, Glucan 1,4-alpha-glucosidase, glucoamylase, glucoamylase 1, glucoamylase 2, glucoamylase C, glucoamylase D, glucoamylase G1, glucoamylase GA15A, glucoamylase P, glucose amylase, GluR, glycoamylase, HjGA, HrGA, lysosomal alpha-glucosidase, maltase glucoamylase, maltase-glucoamylase, maltooligosaccharide-metabolizing enzyme, Meiotic expression upregulated protein 17, MGA, MGAM, More, PDE_05527, PoGA, PoGA15A, PoxGA15A, raw starch-degrading enzyme, raw starch-degrading glucoamylase, RSDE, RSDG, SBD, Sga1, SSG, Sta1, Sta1p, starch-digesting glucoamylase, TagA, tGA, TmGLA, TmGlu1, TtcGA

ECTree

     3 Hydrolases
         3.2 Glycosylases
             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
                3.2.1.3 glucan 1,4-alpha-glucosidase

Activating Compound

Activating Compound on EC 3.2.1.3 - glucan 1,4-alpha-glucosidase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2,2'-dipyridyl
-
stimulates at 1 mM or at 10 mM
2-mercaptoethanol
Ba2+
-
1 mM, 108% of inital activity
beta-mercaptoethanol
-
1 mM
Ca2+
activates at above 5 mM
chloroform
-
50%, 2fold higher activity compared to water as solvent
Cu2+
activates at 1 mM, inhibits at above 5 mM
DMSO
endophytic fungus EF6
-
-
Fe2+
activates at 1 mM
glycerol
endophytic fungus EF6
-
-
Guanidine-HCl
-
1 M, 1156% increase in activity
hexane
-
50%, 2fold higher activity compared to water as solvent
iodoacetamide
-
stimulates
Mn2+
-
1 mM, 105% of inital activity
n-dodecane
-
50%, 2fold higher activity compared to water as solvent
Na2HPO4
-
5 mM, 120% of initial activity
Na2WO4
-
slight stimulation
Pb2+
activates at 1 mM, inhibits at above 5 mM
Pefabloc SC
-
5 mM, 129% increase in activity
Schardinger dextrin
-
slight stimulation of activity with maltose as substrate
sorbitol
-
presence of sorbitol and trehalose significantly increase the substrate affinity and catalytic efficiency of glucoamylases GAM-1 and GAM-2
trehalose
-
presence of sorbitol and trehalose significantly increase the substrate affinity and catalytic efficiency of glucoamylases GAM-1 and GAM-2
Triton X-100
-
0.1%, 162% increase in activity
additional information
-