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3.2.1.28: alpha,alpha-trehalase

This is an abbreviated version!
For detailed information about alpha,alpha-trehalase, go to the full flat file.

Word Map on EC 3.2.1.28

Reaction

alpha,alpha-trehalose
+
H2O
=
beta-D-glucose
+
alpha-D-glucose

Synonyms

acid (non regulatory) trehalase, acid non-regulatory trehalase, acid trehalase, alkaline trehalase, alpha,alpha glucoside 1-glucohydrolase, alpha,alpha trehalase, alpha,alpha trehalose glucohydrolase, alpha,alpha'-trehalose 1-D-glucohydrolase, Alpha,alpha-trehalase, Alpha,alpha-trehalose glucohydrolase, alpha-glucoside-1-glucohydrolase, ATC1, Atc1p, Ath1, ATHA, ATM1, GH37 trehalase, glucose alpha-1,1-glucose hydrolase, HaTre-1, HaTreh-1, Hl-Tre, membrane-bound SfTre2, MSMEG 4528, neutral regulatory trehalase, neutral trehalase, NT-INV, Ntc1p, NTH1, Nth1p, Nth2p, NTHA, Ntp1p, Px_EclTre, Saci_1816, SeTre-1, SeTre-2, SfTre1, soluble P I type trehalase, soluble P II type trehalase, soluble trehalase, THA, Tre-2, TRE1, Tre37A, TreA, treB, TreF, Treh, Treh1, Treh2, trehalase, trehalase-1, trehalase-invertase, TreZ

ECTree

     3 Hydrolases
         3.2 Glycosylases
             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
                3.2.1.28 alpha,alpha-trehalase

KI Value

KI Value on EC 3.2.1.28 - alpha,alpha-trehalase

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.00000066 - 0.000012
(1R,2R,3R,6S,7S,7aS)-3-(hydroxymethyl)-6-[[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl]oxy]hexahydro-1H-pyrrolizine-1,2,7-triol
0.0053 - 0.0093
(2R,3R,4R)-3,4-dihydroxy-2-(hydroxymethyl)pyrrolidine
0.0256 - 0.0554
(2R,3R,4R,5R)-3,4-dihydroxy-2-(hydroxymethyl)-5-methylpyrrolidine
0.000157 - 0.01
(2R,3R,4S,5R,6R)-2-[[(1R,2R,5R,6R,7R,7aR)-6,7-dihydroxy-1,5-bis(hydroxymethyl)hexahydro-1H-pyrrolizin-2-yl]oxy]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
0.000022 - 0.000138
(2S,3R,4S,5S,6R)-2-[[(2R,5R,6R,7R,7aR)-6,7-dihydroxy-5-(hydroxymethyl)hexahydro-1H-pyrrolizin-2-yl]oxy]-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
0.000009
1-thiatrehazolin
at 37°C in sodium maleate buffer (75 mM, pH 5.5)
0.00059 - 0.0117
7-deoxycasuarine
0.033 - 0.107
7-homocasuarine
0.21 - 0.22
amygdalin
0.00486 - 0.0067
castanospermine
0.00012
casuarine
-
pH 6.5, 30°C
7
D-glucose
at 65°C, in 50 mM Bis/Tris/propane-HCl buffer (pH 6.5)
0.00139
deoxynojirimycin
-
pH 6.5, 30°C
1.4
glucono-delta-lactone
at pH 6.0 and 30°C
1.14
mandelonitrile
-
pH 6.0, 30°C
9
mannitol
-
at pH 5.5 and 55°C
0.043
methyl-alpha-D-mannoside
at pH 6.0 and 30°C
89
methyl-alpha-glucoside
-
pH 6.0, 30°C
6.2
methyl-alpha-mannoside
-
pH 6.0, 30°C
0.008
phloretin
at pH 6.0 and 30°C
0.09 - 0.5
phlorizin
0.43 - 0.92
prunasin
19 - 190
Salicin
15
sucrose
-
-
0.55
Tris
-
pH 6.0, 30°C
0.000045
validamycin
-
-
0.000003 - 0.4
validamycin A
0.27
validamycin B
-
pH 3.3, 37°C, versus trehalose
0.0000019 - 0.0032
validoxylamine A
0.0103
validoxylamine B
-
pH 3.3, 37°C, versus trehalose
7
Zn2+
-
at pH 5.5 and 55°C
additional information
additional information
-
inhibition kinetics
-