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3.2.1.25: beta-mannosidase

This is an abbreviated version!
For detailed information about beta-mannosidase, go to the full flat file.

Word Map on EC 3.2.1.25

Reaction

Manbeta1-4GlcNAcbeta(1-4)GlcNAcbeta-Asn
+
H2O
=
GlcNAc-(1-4)-beta-GlcNAc-Asn
 +
beta-D-mannopyranose

Synonyms

beta-D-mannosidase, beta-MAN, beta-mannosidase, beta-mannosidase 2A, beta-mannoside mannohydrolase, betaMANNOS1, BglB, CmMan5, CmMan5a, exo beta-mannanase, exo-beta-D-mannanase, GH2 beta-mannosidase, GM-1, GM-2, HvBII, Man2A, ManB, mannanase, mannase, mannosidase 5A, mannosidase, beta-, OT-1, PH0501, TM1624

ECTree

     3 Hydrolases
         3.2 Glycosylases
             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
                3.2.1.25 beta-mannosidase

Activating Compound

Activating Compound on EC 3.2.1.25 - beta-mannosidase

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ACTIVATING COMPOUND
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
2-mercaptoethanol
Ca2+
1 mM, activation to 108% of control
dithiothreitol
1 mM, activation to 154% of control
Fe2+
1 mM, activation to 105% of control
K+
1 mM, activation to 193 % of control
Li+
1 mM, activation to 187% of control
N-bromosuccinimide
1 mM, activation to 177% of control
Na+
1 mM, activation to 180% of control
Ni2+
1 mM, activation to 144% of control
p-nitrophenyl-alpha-D-mannopyranoside
-
activates at low concentration, competitively inhibits at higher concentrations, 2-3 mM
SDS
1 mM, activation to 148% of control
Sr2+
1 mM, activation to 203% of control