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3.2.1.24: alpha-mannosidase

This is an abbreviated version!
For detailed information about alpha-mannosidase, go to the full flat file.

Word Map on EC 3.2.1.24

Reaction

2-O-alpha-D-mannopyranosyl-D-mannopyranose
+
H2O
= 2 alpha-D-mannopyranose

Synonyms

1,2-alpha-D-mannosidase, 1,2-alpha-mannosidase, acid alpha-mannosidase, acidic alpha-mannosidase, alpha 1,2-mannosidase, Alpha mannosidase 6A8B, alpha-1,2-mannosidase, alpha-1,3 mannosidase, alpha-1,4 mannosidase, alpha-D-mannopyranosidase, alpha-D-mannosidase, Alpha-D-mannoside mannohydrolase, alpha-man, alpha-mann, alpha-mannosidase, alpha-mannosidase C, alpha-mannosidase E-II, alpha-mannosidase I, alpha-mannosidase IA, alpha-mannosidase II, alpha-mannosidase III, alpha1,2-mannosidase, AMAN, class II alpha-mannosidase, CpGH125, ER-alpha-mannosidase, ER-mannosidase II, exo-alpha-mannosidase, GH38 alpha-mannosidase, GH38 alpha-mannosidase II, GH38 class II alpha-mannosidase, GH38 enzyme, Golgi alpha-mannosidase II, Golgi mannosidase IA, Golgi mannosidase IB, Laman, Lysosomal acid alpha-mannosidase, lysosomal alpha-D-mannosidase, lysosomal alpha-mannosidase, Man1p, MAN2B1, Man2C1, Man2C1 alpha-mannosidase, ManA, mannanase, MGG_00994.6, More, neutral alpha-mannosidase, neutral/cytosol mannosidase, p-nitrophenyl-alpha-mannosidase, SpGH125, SpGH38, Ssa-man, SSO3006, TM1851, TMM, velmanase alfa

ECTree

     3 Hydrolases
         3.2 Glycosylases
             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
                3.2.1.24 alpha-mannosidase

Molecular Weight

Molecular Weight on EC 3.2.1.24 - alpha-mannosidase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
100000
-
2 * 100000, reducing SDS-PAGE, catalytic subunit
110000
111500
2 * 111500, gel filtration
113000
-
Tris-eluted isoform from cobalt-chelating Sepharose, gel filtration
115000
-
4 * 115000, SDS-PAGE
116000
120000
124000
-
2 * 124000, SDS-PAGE
150000
-
gel filtration
154000
-
gel filtration
185000 - 200000
-
chymotrypsin-cleaved catalytic subunit, non-reducing SDS-PAGE, gel filtration
188000 - 197000
-
gel filtration, sucrose density gradient centrifugation
200000
-
gel filtration, sucrose density gradient centrifugation
217000
-
gel filtration
220000
230000
240000
-
gel filtration
26000
-
alpha3beta3, 3 * 62000 + 3 * 26000, SDS-PAGE, alpha-mannosidase A
260000
270000
275000
280000
285000
-
gel filtration
290000
295000
-
gel filtration
30000 - 32000
-
gel filtration, sedimentation equilibrium centrifugation
300000
329000
-
gel filtration
335000
-
gel filtration
359000
-
gel filtration
363000
gel filtration
372000 - 420000
-
sucrose density gradient centrifugation, gel filtration
412000
-
gel filtration
417000
-
gel filtration
42000
-
SDS-PAGE, non-denaturating electrophoresis
43000
-
1 * 43000, SDS-PAGE
44000
45000
450000
-
gel filtration
460000
-
gel filtration
47000
-
2 * 70000, L-subunit, + 2 * 47000, S-subunit, SDS-PAGE
480000
-
gel filtration
49000
-
gel filtration
50000
-
1 * 75000 + 1 * 60000 + 1 * 50000 + 1 * 45000, SDS-PAGE
500000
-
non-denaturating PAGE
51000
53000
-
SDS-PAGE
54300
-
enzyme I, SDS-PAGE
560000
-
gel filtration
57000
-
calculated from amino acid sequence
58000
-
4 * 58000, SDS-PAGE
60000
-
1 * 75000 + 1 * 60000 + 1 * 50000 + 1 * 45000, SDS-PAGE
61200
-
MALDI-TOF mass spectrometry
62000
-
alpha3beta3, 3 * 62000 + 3 * 26000, SDS-PAGE, alpha-mannosidase A
63000
66000
670000
gel filtration
69200
-
6 * 69200, SDS-PAGE
70000
75000
93300
-
enzyme II, SDS-PAGE