3.2.1.23: beta-galactosidase
This is an abbreviated version!
For detailed information about beta-galactosidase, go to the full flat file.
Word Map on EC 3.2.1.23
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3.2.1.23
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lacz
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adenovirus
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lysosomal
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lactose
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endothelial
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oligosaccharide
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artery
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phage
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adenovirus-mediated
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beta-glucosidase
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immunoassay
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retroviral
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beta-glucuronidase
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herpes
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lambda
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simplex
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luciferase
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cytomegalovirus
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neuraminidase
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viruses
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hydrolases
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bacteriophage
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glycosidases
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gm1
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liposome
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ganglioside
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p16ink4a
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alpha-galactosidase
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alpha-mannosidase
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osteogenic
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vaccinia
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adeno-associated
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replication-defective
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n-acetyl-beta-glucosaminidase
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runx2
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sialidase
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alpha-glucosidase
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sialic
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galactosylation
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plaque-forming
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osteoblast
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kluyveromyces
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telomerase
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analysis
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degradation
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diagnostics
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lysogens
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beta-hexosaminidase
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keratan
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vector-mediated
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biotechnology
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molecular biology
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synthesis
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environmental protection
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ganciclovir
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nutrition
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transglycosylation
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medicine
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industry
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nonviral
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food industry
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biofuel production
- 3.2.1.23
- lacz
- adenovirus
- lysosomal
- lactose
- endothelial
- oligosaccharide
- artery
- phage
-
adenovirus-mediated
- beta-glucosidase
-
immunoassay
-
retroviral
- beta-glucuronidase
-
herpes
- lambda
- simplex
- luciferase
- cytomegalovirus
- neuraminidase
- viruses
- hydrolases
- bacteriophage
- glycosidases
- gm1
- liposome
- ganglioside
- p16ink4a
- alpha-galactosidase
- alpha-mannosidase
-
osteogenic
- vaccinia
-
adeno-associated
-
replication-defective
- n-acetyl-beta-glucosaminidase
- runx2
- sialidase
- alpha-glucosidase
-
sialic
-
galactosylation
-
plaque-forming
-
osteoblast
- kluyveromyces
- telomerase
- analysis
- degradation
- diagnostics
-
lysogens
- beta-hexosaminidase
- keratan
-
vector-mediated
- biotechnology
- molecular biology
- synthesis
- environmental protection
- ganciclovir
- nutrition
-
transglycosylation
- medicine
- industry
-
nonviral
- food industry
- biofuel production
Reaction
Synonyms
Aabeta-gal, Acid beta-galactosidase, B-GAL, BbgI, BbgII, BbgIII, BbgIV, beta galactosidase, beta-D-galactohydrolase, beta-D-galactosidase, beta-D-galactoside galactohydrolase, beta-D-glactanase, beta-D-lactosidase, beta-gal, beta-Gal 1, beta-Gal 2, beta-Gal II, beta-galactosidase, beta-galactosidase I, beta-galactosidase II, beta-galactosidase III, beta-galactosidase IV, beta-galase, beta-lactosidase, betagal, betaGly4, betaGS, BGA, BgaB, BgaBM, bgaD, BgaH, BGAL, BGAL1, BGAL10, BGAL11, BGAL12, BGAL13, BGAL14, BGAL15, BGAL16, BGAL17, BGAL2, BGAL3, BGAL4, BGAL5, BGAL6, BGAL7, BGAL8, BGAL9, BgalA, BgAP, BgaS, BgaX, BGL1, BglAp, BGT I, BGT II, cold-active beta-galactosidase, CTP-beta-gal, driselase, EABase, endo-beta-galactosidase, Exo-(1-->4)-beta-D-galactanase, exo-beta-(1->3)-D-galactanase, Gal-2, Gal-5, GAL1, Gal2, Gal3, Gal4, GALA, galactanase, galactosidase, galactosidase, beta, GALB, gherkin lactase, H-BgaS, hcbetagal, Hlac_2868, Hydrolact, LacA, LACS, lactase, lactase phlorizin hydrolase, lactosylceramidase II, Lactozym, Lactozym 3000L, LPH, Maxilact, Maxilact-L/2000, MeBglD2, More, ONPGase, Oryzatym, p-nitrophenyl beta-galactosidase, PF1208, PRGH1, S 2107, SA-beta-GAL, SA-betagal, senescence-associated beta-galactosidase, SPD_0065 protein, SR12 protein, Ss beta-gal, SSO3019, SSU0587, Sumiklat, Trilactase, XC1214, XG-specific beta-galactosidase, YesZ, YH4502, ZD410
ECTree
3.2.1.23 beta-galactosidaseAdvanced search results
results (
results (Natural Substrates Products
Natural Substrates Products on EC 3.2.1.23 - beta-galactosidase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
galactan + H2O
?
-
the GHF 42 enzyme LacA can act on the oligosaccharides released by the GH53 enzyme GalA from galactan, overview
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-
?
galactotetraose + H2O
beta-D-galactose
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the GHF 42 enzyme LacA can act on the oligosaccharides released by the GH53 enzyme GalA from galactan, overview
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-
?
lactose + H2O
D-galactose + D-glucose + oligosaccharide
under simulated gastric conditions, BgalA has greater stability (about 100%) and hydrolysis ratio (more than 80%) toward milk lactose than the commercially available beta-galactosidase from Aspergillus oryzae (ATCC 20423)
the main products of lactose hydrolysis by recombinant BgalA are 19.5% D-galactose, 72.5% D-glucose, and 8.0% oligosaccharide
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?
xyloglucan oligosaccharides + H2O
?
-
the enzyme hcbetagal is involved in storage xyloglucan mobilisation during seedling development, hcbetagal might be one of the biochemical control points in xyloglucan catabolism in vivo
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-
?
a beta-D-galactoside + H2O
D-galactose + an alcohol
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-
-
-
?
a beta-D-galactoside + H2O
D-galactose + an alcohol
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-
-
-
?
lactose + H2O
beta-D-glucose + beta-D-galactose
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the enzyme is involved in the lactose metabolism of the organism, overview
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-
?
lactose + H2O
D-glucose + D-galactose
the enzyme is involved in lactose degradation in milk
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-
?
lactose + H2O
D-glucose + D-galactose
the enzyme is involved in lactose degradation in milk
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-
?
lactose + H2O
D-glucose + D-galactose
the enzyme is involved in lactose hydrolysis in the small intestine of the host organism
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-
?
lactose + H2O
D-glucose + D-galactose
-
the enzyme is involved in lactose fermentation in the colon playing a central role in lactose intolerance in humans
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-
?
lactose + H2O
D-glucose + D-galactose
-
the enzyme is involved in lactose fermentation in the colon playing a central role in lactose intolerance in humans
-
-
?
lactose + H2O
D-glucose + D-galactose
-
the enzyme is involved in lactose fermentation in the colon playing a central role in lactose intolerance in humans
-
-
?
lactose + H2O
D-glucose + D-galactose
-
the enzyme is involved in lactose fermentation in the colon playing a central role in lactose intolerance in humans
-
-
?
lactose + H2O
D-glucose + D-galactose
-
the enzyme is involved in lactose fermentation in the colon playing a central role in lactose intolerance in humans
-
-
?
lactose + H2O
D-glucose + D-galactose
-
the enzyme is involved in lactose fermentation in the colon playing a central role in lactose intolerance in humans
-
-
?
lactose + H2O
D-glucose + D-galactose
-
the enzyme is involved in lactose fermentation in the colon playing a central role in lactose intolerance in humans
-
-
?
lactose + H2O
D-glucose + D-galactose
-
the enzyme is involved in lactose fermentation in the colon playing a central role in lactose intolerance in humans
-
-
?
lactose + H2O
D-glucose + D-galactose
-
the enzyme is involved in lactose fermentation in the colon playing a central role in lactose intolerance in humans
-
-
?
lactose + H2O
D-glucose + D-galactose
-
the enzyme is involved in lactose fermentation in the colon playing a central role in lactose intolerance in humans
-
-
?
lactose + H2O
D-glucose + D-galactose
-
the enzyme is involved in lactose fermentation in the colon playing a central role in lactose intolerance in humans
-
-
?
lactose + H2O
D-glucose + D-galactose
-
the enzyme is involved in lactose fermentation in the colon playing a central role in lactose intolerance in humans
-
-
?
lactose + H2O
D-glucose + D-galactose
-
the enzyme is involved in lactose fermentation in the colon playing a central role in lactose intolerance in humans
-
-
?
lactose + H2O
D-glucose + D-galactose
-
the enzyme is involved in lactose fermentation in the colon playing a central role in lactose intolerance in humans
-
-
?
lactose + H2O
D-glucose + D-galactose
-
the enzyme is involved in lactose fermentation in the colon playing a central role in lactose intolerance in humans
-
-
?
lactose + H2O
D-glucose + D-galactose
Limosilactobacillus reuteri MEP181R88
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the enzyme is involved in lactose fermentation in the colon playing a central role in lactose intolerance in humans
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-
?
lactose + H2O
D-glucose + D-galactose
-
the enzyme is involved in lactose fermentation in the colon playing a central role in lactose intolerance in humans
-
-
?
lactose + H2O
D-glucose + D-galactose
Limosilactobacillus vaginalis MEP181R91
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the enzyme is involved in lactose fermentation in the colon playing a central role in lactose intolerance in humans
-
-
?
xyloglucan oligosaccharide + H2O
galactopyranose + xyloglucan oligosaccharide
the combinations of beta-galactosidase LacA and isoprimeverose-producing oligoxyloglucan hydrolase IpeA is crucial for xyloglucan degradation. Specifically, the combination of LacA and IpeA is a key step in the degradation of xyloglucan oligosaccharides, because IpeA requires LacA for the removal of galactopyranosyl residues, which prevent IpeA activity, and LacA requires IpeA for the removal of isoprimeverose units, which interfere with the formation of the LacA-xyloglucan oligosaccharide complex
-
-
?
xyloglucan oligosaccharide + H2O
galactopyranose + xyloglucan oligosaccharide
the combinations of beta-galactosidase LacA and isoprimeverose-producing oligoxyloglucan hydrolase IpeA is crucial for xyloglucan degradation. Specifically, the combination of LacA and IpeA is a key step in the degradation of xyloglucan oligosaccharides, because IpeA requires LacA for the removal of galactopyranosyl residues, which prevent IpeA activity, and LacA requires IpeA for the removal of isoprimeverose units, which interfere with the formation of the LacA-xyloglucan oligosaccharide complex
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-
?
additional information
?
-
-
regulation and physiologic functions of LacA and GalA, GH42 and GH53 enzymes, overview
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-
?
additional information
?
-
Corynebacterium murisepticum
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the enzyme is inducible by lactose and galactose
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-
?
additional information
?
-
-
the enzyme stimulates the proliferation of T cells from allergic subjects, and favor the emergence of CD4+ T cell clones with specific in vitro reactivity to beta-galactosidase. The enzyme may represent the major native allergen among Mediterranean trees
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-
?
additional information
?
-
-
the enzyme stimulates the proliferation of T cells from allergic subjects, and favor the emergence of CD4+ T cell clones with specific in vitro reactivity to beta-galactosidase. The enzyme may represent the major native allergen among Mediterranean trees
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-
?
additional information
?
-
-
patients with type 1 HM1 gangliosidosis (mutation D332N on one allele and mutation S532G on the other allele) have less than 1% residual beta-galactosidase activity and minimal detectable levels of immunoreactive beta-galactosidase protein in fibroblasts. Most of the missense mutations described in GM1 gangliosidosis have little effect on catalytic activity, but do affect protein conformation such that the resulting protein cannot be transported out of the ER and fails to arrive in the lysosome. This accounts for the minimal amounts of the enzyme protein and activity seen in most GM1 gangliosidosis patient fibroblast
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-
?
additional information
?
-
-
the enzyme activity is correlated with the senescence of cells, overview
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-
?
additional information
?
-
-
addition of lactose to the growth medium containing galactose inhibits enzyme synthesis
-
-
?
additional information
?
-
-
the enzyme stimulates the proliferation of T cells from allergic subjects, and favor the emergence of CD4+ T cell clones with specific in vitro reactivity to beta-galactosidase. The enzyme may represent the major native allergen among Mediterranean trees
-
-
?
additional information
?
-
-
degalactosylation of peanut agglutinin-positive glycoprotein of MW 130000-150000 Da, present in the caput sperm
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-
?
additional information
?
-
-
the enzyme along with other exoglycohydrolases and proteases, is thought to aid in penetration of the zona pellucida, the extracellular glycocalyx that surrounds the mammalian egg
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-
?
