3.2.1.20: alpha-glucosidase

This is an abbreviated version!
For detailed information about alpha-glucosidase, go to the full flat file.

Reaction

Synonyms

6-phospho-alpha-glucosidase, AAGR-1, AAGR-2, AAGR-3, AAGR-4, acid alpha-glucosidase, acid alpha-glucoside hydrolase, acid GAA, acid maltase, acidic alpha-glucosidase, AG, AgdB, AGL, AglA, aGlu, alglucosidase alfa, alpha-1,4-glucosidase, alpha-D-glucosidase, alpha-D-glucoside glucohydrolase, alpha-GD, alpha-glucopyranosidase, alpha-glucosid-specific GH4 enzyme, alpha-glucosidase, alpha-glucosidase B, alpha-glucosidase I, alpha-glucosidase II, alpha-glucosidase III, alpha-glucosidase MAL12, alpha-glucosidase MAL32, alpha-glucosidase type I, alpha-glucosidase type IV, alpha-glucoside glucohydrolase, alpha-glucoside hydrolase, alpha-transglucosidase, alphaGlu1, alphaGlu2, alphaGlu3, alphaGluFa, Amy112, CHEI, CWH41, exo-alpha-l, 4-glucosidase, exo-alpha-l,4-glucosidase, GAA, GH13 alpha-glucosidase, GluA, glucoamylase, glucoinvertase, glucosidoinvertase, glucosidosucrase, GlyFa1, GlyFa2, GSJ, HBG III, HBGase I, HBGase II, HBGase III, high pI alpha-glucosidase, intestinal alpha-glucosidase, intestinal maltase, JHGase I, MAL12, MAL2, MAL32, MalA, MalH, maltase, maltase glucoamylase, maltase-glucoamylase, maltodextrin glucosidase, MalZ, MGAM, More, myozyme, NAG, neutral alpha-glucosidase, PalH, Pars_2044, phospho-alpha-glucosidase, R-glucosidase, recombinant human GAA, rhGAA, Saci1160, st2525, Ta0298, TcaAG, TtGluA

ECTree

     3 Hydrolases

         3.2 Glycosylases

             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds

                3.2.1.20 alpha-glucosidase

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Results	in table
37	Activating Compound
8609	AA Sequence
53	Application
1	CAS Registry Number
64	Cloned(Commentary)
1	Cofactor
7	Crystallization (Commentary)
3667	Disease/ Diagnostics
7	Expression
20	General Information
14	General Stability
268	IC50 Value
900	Inhibitors
72	kcat/KM [mM/s]
100	Ki Value [mM]
460	KM Value [mM]
105	Localization
52	Metals/Ions
193	Molecular Weight [Da]
77	Natural Substrates/ Products (Substrates)
3	Organic Solvent Stability
424	Organism
10	Pathway
115	PDB ID
197	pH Optimum
58	pH Range
52	pH Stability
12	pI Value
36	Posttranslational Modification
71	Protein Variants
131	Purification (Commentary)
8	Reaction
23	Reaction Type
328	Reference
1	Renatured (Commentary)
133	Source Tissue
161	Specific Activity [micromol/min/mg]
13	Storage Stability
1192	Substrates and Products (Substrate)
133	Subunits
251	Synonyms
1	Systematic Name
153	Temperature Optimum [°C]
41	Temperature Range [°C]
135	Temperature Stability [°C]
163	Turnover Number [1/s]

Organism

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Organism on EC 3.2.1.20 - alpha-glucosidase

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ORGANISM

COMMENTARY

LITERATURE

UNIPROT

SEQUENCE DB

SOURCE

Acarus siro

-

707289

-

-

brenda

Aleuroglyphus ovatus

-

707289

-

-

brenda

Alkalihalophilus pseudofirmus

-

750760

A0A1S6JYL1

UniProt

brenda

Alkalihalophilus pseudofirmus 703

-

750760

A0A1S6JYL1

UniProt

brenda

Allium fistulosum

-

393277

-

-

brenda

Amylomyces rouxii

-

393309

-

-

brenda

Anopheles aquasalis

adult female mosquitos, three isozymes alphaGlu1-alpha-Glu3

679317

-

-

brenda

Apis cerana indica

gene AciHBGase II

731543

J9SJ08

UniProt

brenda

Apis cerana japonica

2 entries

Apis florea

dwarf honeybee

680164

A5JVZ2

SwissProt

brenda

Apis mellifera

3 entries

Aplysia fasciata

-

665788

-

-

brenda

Arabidopsis sp.

at least 3 alpha-glucosidases

393335

-

-

brenda

Aspergillus awamori

-

136210

-

-

brenda

Aspergillus fumigatus

-

393307

-

-

brenda

Aspergillus nidulans

alpha-glucosidase B, i.e. AgdB

654259

Q9C1S7

SwissProt

brenda

Aspergillus nidulans ABPU1

alpha-glucosidase B, i.e. AgdB

654259

Q9C1S7

SwissProt

brenda

Aspergillus niger

7 entries

Aspergillus niger GN-3

gene aglA

665337

P56526

Uniprot

brenda

Aspergillus niveus

-

707184

-

-

brenda

Aureobasidium pullulans

color variant strain

393349

-

-

brenda

Bacillus amyloliquefaciens

-

393270, 393292

-

-

brenda

Bacillus cereus

-

393306

-

-

brenda

Bacillus licheniformis

3 entries

Bacillus licheniformis KIBGE-IB4

-

729415

-

-

brenda

Bacillus sp. (in: Bacteria)

2 entries

Bacillus sp. (in: Bacteria) SAM1606

SAM1606

393346

-

-

brenda

Bacillus subtilis

-

136522, 393350

-

-

brenda

Bacillus thermoamyloliquefaciens

3 alpha-glucosidases I, II, and III

654988

Q9F234

SwissProt

brenda

Bacillus thuringiensis serovar kurstaki

-

663905

-

-

brenda

Bacillus thuringiensis serovar kurstaki HD-1

-

663905

-

-

brenda

Bacteroides thetaiotaomicron

95-1

393353

-

-

brenda

Bacteroides thetaiotaomicron 95-1

95-1

393353

-

-

brenda

Beta vulgaris

2 entries

Bifidobacterium adolescentis

strain ATCC 15703

681521

-

-

brenda

Bifidobacterium longum subsp. Longum

-

750843

-

-

brenda

Bifidobacterium longum subsp. Longum JCM1217

-

750843

-

-

brenda

Bos taurus

cattle

393323

-

-

brenda

Brassica napus

-

393335

-

-

brenda

Brassica oleracea

-

393335

-

-

brenda

Caenorhabditis elegans

-

709928

-

-

brenda

Caldanaerobacter subterraneus subsp. tengcongensis

gene gluA

717884

Q8RDL1

UniProt

brenda

Caldanaerobacter subterraneus subsp. tengcongensis MB4

-

709498

Q8RDL1

UniProt

brenda

Caloglyphus redickorzevi

-

707289

-

-

brenda

Camelus dromedarius

-

679331

-

-

brenda

Candida albicans

-

701754

Q2V621

UniProt

brenda

Carpoglyphus lactis

-

707289

-

-

brenda

Chilo suppressalis

-

702988

-

-

brenda

Chortoglyphus arcuatus

-

707289

-

-

brenda

Crithidia fasciculata

sandfly, Phlebotomus papatasi, infected

393357, 393550

-

-

brenda

Cronobacter sakazakii

two isozymes encoded by genes gluA and gluB

682887

-

-

brenda

Cronobacter sakazakii 858

two isozymes encoded by genes gluA and gluB

682887

-

-

brenda

Cyberlindnera fabianii

-

717136

E1CJT1

UniProt

brenda

Cyberlindnera fabianii J640

-

717136

E1CJT1

UniProt

brenda

Dermatophagoides farinae

-

707289

-

-

brenda

Drosophila melanogaster

-

393287

-

-

brenda

Dysdercus peruvianus

-

393341

-

-

brenda

Entamoeba histolytica

-

654210, 655752

-

-

brenda

Entamoeba histolytica HM1:IMSS

-

654210, 655752

-

-

brenda

Equus caballus

-

393319

-

-

brenda

Erwinia rhapontici

2 entries

Erwinia rhapontici DSM 448

strain DSM448, gene palH

705622

Q9AI65

UniProt

brenda

Escherichia coli

2 entries

Fagopyrum esculentum

-

393299, 393311

-

-

brenda

Ferroplasma acidiphilum

2 entries

Ferroplasma acidiphilum DSM 12658

-

729158

Q5K3Q3

UniProt

brenda

Geobacillus sp.

2 entries

Geobacillus sp. HTA-462

-

695045

Q33E90

UniProt

brenda

Geobacillus stearothermophilus

3 entries

Geobacillus stearothermophilus ATCC 12016

strain ATCC12016

680563

-

-

brenda

Geobacillus stearothermophilus U2

2 entries

Geobacillus thermodenitrificans

-

665791

-

-

brenda

Geobacillus thermodenitrificans HRO10

-

665791

-

-

brenda

Glycine max

L. cv. Tamanishiki

393274

-

-

brenda

Haloquadratum walsbyi

-

751439

-

-

brenda

Haloquadratum walsbyi DSM 16854

-

751439

-

-

brenda

Herpetomonas muscarum

sandfly, Phlebotomus papatasi, infected

393357, 393550

-

-

brenda

Homo sapiens

12 entries

Hordeum vulgare

4 entries

Lactobacillus acidophilus

IFO 3532

393279

-

-

brenda

Leishmania braziliensis

sandfly, Phlebotomus papatasi, infected

393357, 393550

-

-

brenda

Leishmania donovani

sandfly, Phlebotomus papatasi, infected

393357, 393550

-

-

brenda

Leishmania infantum

sandfly, Phlebotomus papatasi, infected

393357, 393550

-

-

brenda

Leishmania major

sandfly, Phlebotomus papatasi, infected

393357, 393550

-

-

brenda

Lentinula edodes

Berk. Sing.

393291

-

-

brenda

Lepidoglyphus destructor

-

707289

-

-

brenda

Levilactobacillus brevis

-

393351

-

-

brenda

Lipomyces starkeyi

CBS 1809

393269

-

-

brenda

Lipomyces starkeyi CBS 1809

CBS 1809

393269

-

-

brenda

Malbranchea cinnamomea

-

393354

-

-

brenda

Mesotaenium caldariorum

-

393265

-

-

brenda

Microbacterium soli sp. nov.

-

708799

-

-

brenda

Mortierella alliacea

-

655023

-

-

brenda

Mortierella alliacea YN-15

-

655023

-

-

brenda

Mougeotia sp.

-

393265

-

-

brenda

Mucor javanicus

-

393300, 393301, 393302

-

-

brenda

Mucor racemosus

-

393296, 393297

-

-

brenda

Mus musculus

3 entries

Oncorhynchus mykiss

3 alpha-glucosidase, acid type I, acid type II and neutral enzyme

393342

-

-

brenda

Oryctolagus cuniculus

-

393260

-

-

brenda

Oryza sativa

5 entries

Paecilomyces variotii

CMI 1696

393266

-

-

brenda

Paecilomyces variotii CMI 1696

CMI 1696

393266

-

-

brenda

Paenibacillus amylolyticus

-

393283

-

-

brenda

Panicum miliaceum

alpha-glucosidase II in germinating seeds

666565

-

-

brenda

Parageobacillus thermoglucosidasius

-

393303

-

-

brenda

Parageobacillus thermoglucosidasius KP 1006

-

393303

-

-

brenda

Penicillium brevicompactum

-

393278

-

-

brenda

Penicillium citrinum

-

393278

-

-

brenda

Penicillium oxalicum

-

393298

-

-

brenda

Phaffia rhodozyma

several strains

667019

-

-

brenda

Picrophilus torridus

strain DSM 9790, gene aglA

680469

Q6L2X4

SwissProt

brenda

Pisum sativum

3 alpha-glucosidases: alpha-glucosidase 1, alpha-glucosidase 2, alpha-glucosidase 3

393339

-

-

brenda

Purpureocillium lilacinum

-

655050

-

-

brenda

Purpureocillium lilacinum HKS-124

-

655050

-

-

brenda

Pyrobaculum arsenaticum

-

750601

A4WMH3

UniProt

brenda

Pyrobaculum arsenaticum DSM 13514

-

750601

A4WMH3

UniProt

brenda

Pyrococcus furiosus

2 entries

Pyrococcus woesei

-

656703

-

-

brenda

Quesada gigas

-

708224

-

-

brenda

Rana japonica

-

136220

-

-

brenda

Rattus norvegicus

-

136510, 393281, 393317, 393320, 393324, 664319, 678601, 678697, 681559, 692721, 694604, 707664, 709294

-

-

brenda

Rhizobium sp.

-

393333

-

-

brenda

Rhizobium sp. USDA 4280

-

393333

-

-

brenda

Rhodnius prolixus

-

710374

B6V6H0

UniProt

brenda

Saccharolobus solfataricus

7 entries

Saccharolobus solfataricus 98/2

2 entries

Saccharolobus solfataricus MT-4 / DSM 5833

-

656561, 678834

-

-

brenda

Saccharolobus solfataricus MT4

-

724871

-

-

brenda

Saccharomyces cerevisiae

8 entries

Saccharomyces cerevisiae ATCC 204508

2 entries

Saccharomyces logos

-

393308

-

-

brenda

Saccharomyces pastorianus

-

393290

-

-

brenda

Saccharomycopsis fibuligera

KZ

393328

-

-

brenda

Saccharomycopsis fibuligera KZ

KZ

393328

-

-

brenda

Schizosaccharomyces pombe

2 entries

Sinorhizobium meliloti

-

748072

Q9Z3R8

UniProt

brenda

Solanum tuberosum

2 entries

Sulfolobus acidocaldarius

-

725283

Q4J9M3

UniProt

brenda

Sulfolobus acidocaldarius DSM 639

-

725283

Q4J9M3

UniProt

brenda

Sulfurisphaera tokodaii

-

722938

F9VPH0

UniProt

brenda

Sulfurisphaera tokodaii 7

-

722938

F9VPH0

UniProt

brenda

Sus scrofa

-

393272, 393314, 393315, 393322, 679917

-

-

brenda

Talaromyces purpureogenus

-

393304

-

-

brenda

Tetrahymena pyriformis

-

393275

-

-

brenda

Tetrahymena pyriformis W

-

393275

-

-

brenda

Thermoanaerobacter thermohydrosulfuricus

39E

393347

-

-

brenda

Thermoanaerobacter thermohydrosulfuricus 39E

39E

393347

-

-

brenda

Thermoascus aurantiacus

-

717984, 743072, 743850

-

-

brenda

Thermoascus aurantiacus 179-5

-

743072

-

-

brenda

Thermoascus aurantiacus CBMAI 756

-

717984

-

-

brenda

Thermochaetoides thermophila

var. coprophilum, filamentous fungus, strain ATCC 1645

682602

-

-

brenda

Thermococcus sp.

-

393330, 656703

-

-

brenda

Thermococcus sp. AN1

-

393330, 656703

-

-

brenda

Thermomonospora curvata

-

393356

-

-

brenda

Thermoplasma acidophilum

-

747382, 748424, 748515

Q9HLD0

UniProt

brenda

Thermotoga maritima

enzyme AglA, gene aglA

655516

O33830

SwissProt

brenda

Thermus caldophilus

enzyme TcaAG

655933

-

-

brenda

Thermus caldophilus GK24

enzyme TcaAG

655933

-

-

brenda

Thermus thermophilus HB27

DSM 7039, gene TTC0107

692850

Q745T6

UniProt

brenda

Thermus thermophilus HB27 HB27 / ATCC BAA-163 / DSM 7039

DSM 7039, gene TTC0107

692850

Q745T6

UniProt

brenda

Thermus thermophilus HB8

-

692850

Q5SL12

UniProt

brenda

Trichoderma viride

-

655817

-

-

brenda

Trichoderma viride TvMNT7

-

655817

-

-

brenda

Trichomonas vaginalis

parasitic protist, 2 isozymes 1 and 2

656390

-

-

brenda

Tyroborus lini

-

707289

-

-

brenda

Tyrophagus putrescentiae

-

707289

-

-

brenda

Vigna radiata

-

393285

-

-

brenda

Vitis vinifera

var. Riesling

393289

-

-

brenda

Wickerhamomyces anomalus

-

393278

-

-

brenda

Zea indurata

-

393305

-

-

brenda

Zea mays

2 entries

Zea mays subsp. mays

flint corn

664319

-

-

brenda

Zygnema cylindricum

-

393265

-

-

brenda

[Bacillus] caldovelox

DSM411

393264

-

-

brenda

[Bacillus] caldovelox DSM 411

DSM411

393264

-

-

brenda

Apis cerana japonica

-

678787

A1IHL0

SwissProt

brenda

Apis cerana japonica

alpha-glucosidase I; Japanese honeybee

678787

A1IHL0

SwissProt

brenda

Apis mellifera

-

393348, 393355, 708265

-

-

brenda

Apis mellifera

alpha-glucosidase III

655000

-

-

brenda

Apis mellifera

isozymes HBGase I-III

664319

-

-

brenda

Aspergillus niger

-

393278, 393286, 393340, 664319, 708265

-

-

brenda

Aspergillus niger

-

708849

A2QJF7

UniProt

brenda

Aspergillus niger

-

749475

P56526

Uniprot

brenda

Aspergillus niger

-

749692, 750602

A0PCH8

UniProt

brenda

Aspergillus niger

-

750893

A2QJF7

UniProt

brenda

Aspergillus niger

ATCC 42418

393345

-

-

brenda

Aspergillus niger

gene aglA

665337

P56526

Uniprot

brenda

Bacillus licheniformis

-

729415

-

-

brenda

Bacillus licheniformis

NCIB 6346

393276

-

-

brenda

Bacillus licheniformis

resolution of the alpha-glucosidase system into two enzymes: alpha-glucosidase and maltase

393268

-

-

brenda

Bacillus sp. (in: Bacteria)

ATCC 21591

393280

-

-

brenda

Bacillus sp. (in: Bacteria)

SAM1606

393346

-

-

brenda

Beta vulgaris

-

393273, 393337, 708265

-

-

brenda

Beta vulgaris

sugar beet

664319

-

-

brenda

Erwinia rhapontici

-

705622

-

-

brenda

Erwinia rhapontici

strain DSM448, gene palH

705622

Q9AI65

UniProt

brenda

Escherichia coli

-

698521

P21517

UniProt

brenda

Escherichia coli

enterophatogenic strains produce significantly more maltase than non-pathogenic strains

393267

-

-

brenda

Ferroplasma acidiphilum

-

729158

Q5K3Q3

UniProt

brenda

Ferroplasma acidiphilum

-

729647

Q2PCE2, Q2PCE3, Q5K3Q3

UniProt

brenda

Geobacillus sp.

-

654072

-

-

brenda

Geobacillus sp.

strains A333, A343, F84a, F84b, E134 and stearothermophilus ATCC 12980, ATCC 43223, ATCC 7953 and thermoglucosidasius DSM 2542

694053

-

-

brenda

Geobacillus stearothermophilus

-

664319, 682301, 693568, 694600, 694604, 708265, 751795

-

-

brenda

Geobacillus stearothermophilus

i.e. Bacillus stearothermophilus

751795

Q9R5L9

UniProt

brenda

Geobacillus stearothermophilus

strain ATCC12016

680563

-

-

brenda

Geobacillus stearothermophilus U2

-

751795

-

-

brenda

Geobacillus stearothermophilus U2

i.e. Bacillus stearothermophilus

751795

Q9R5L9

UniProt

brenda

Homo sapiens

-

393262, 393316, 393321, 393325, 393326, 393327, 393336, 393343

-

-

brenda

Homo sapiens

-

681471

O43451

Uniprot

brenda

Homo sapiens

-

681570

-

-

brenda

Homo sapiens

-

691865

P10253

UniProt

brenda

Homo sapiens

-

693740, 694198, 707102

-

-

brenda

Homo sapiens

-

708660

O43451

Uniprot

brenda

Homo sapiens

-

708841, 714471, 717357

-

-

brenda

Homo sapiens

-

729004

O43451

Uniprot

brenda

Homo sapiens

-

730695, 749578, 749991

-

-

brenda

Homo sapiens

-

751380

P10253

UniProt

brenda

Homo sapiens

alpha-glucosidase AB and alpha-glucosidase C

393318

-

-

brenda

Homo sapiens

patients with infantile Pompe disease

680016

-

-

brenda

Hordeum vulgare

-

393334

-

-

brenda

Hordeum vulgare

-

393338

Q43763

Uniprot

brenda

Hordeum vulgare

-

393344, 718234

-

-

brenda

Hordeum vulgare

gene agl97

666836

Q9LLY2

SwissProt

brenda

Mus musculus

-

681105, 730248

-

-

brenda

Mus musculus

adult male Albino Swiss mice

682809

-

-

brenda

Mus musculus

fragment

681555

Q6XK23, Q6XK24

SwissProt

brenda

Oryza sativa

-

393263, 664319, 708265

-

-

brenda

Oryza sativa

glucosidase I and II

393261, 393310

-

-

brenda

Oryza sativa

L. cultivar Yashiromochi

393284

-

-

brenda

Oryza sativa

L. cv. Shinsetsu

393261, 393310

-

-

brenda

Oryza sativa

Norin No. 16

393271

-

-

brenda

Pyrococcus furiosus

-

393352, 721313

-

-

brenda

Pyrococcus furiosus

strain DSM 3638

656703

-

-

brenda

Saccharolobus solfataricus

-

393331, 656561, 656703, 677717, 678834

-

-

brenda

Saccharolobus solfataricus

-

708265

P0CD66

SwissProt

brenda

Saccharolobus solfataricus

-

719558

D0KQM8

UniProt

brenda

Saccharolobus solfataricus

-

724871, 725229

-

-

brenda

Saccharolobus solfataricus

gene malA

663522

-

-

brenda

Saccharolobus solfataricus

gene malA

666076

P0CD66

SwissProt

brenda

Saccharolobus solfataricus

malA; strains 98/2 and P2, gene malA

680431

P0CD66

SwissProt

brenda

Saccharolobus solfataricus 98/2

-

656703

-

-

brenda

Saccharolobus solfataricus 98/2

-

719558

D0KQM8

UniProt

brenda

Saccharomyces cerevisiae

-

393294, 393295, 664319, 678602, 678618, 678697, 681559, 691229, 691287, 691769, 693568, 693717, 694604, 694610, 707198, 707716, 708081, 708265, 708826, 710484, 717368, 717965

-

-

brenda

Saccharomyces cerevisiae

-

729482

P53341

SwissProt

brenda

Saccharomyces cerevisiae

-

730576, 730843, 749448

-

-

brenda

Saccharomyces cerevisiae

-

751188

P38158

UniProt

brenda

Saccharomyces cerevisiae

-

751188

P53341

SwissProt

brenda

Saccharomyces cerevisiae

-

752119

-

-

brenda

Saccharomyces cerevisiae

strains D-346, ATCC 56960, and 727-14C, ATCC 56959

664827

-

-

brenda

Saccharomyces cerevisiae

type Malaga and type Palestina

393278

-

-

brenda

Saccharomyces cerevisiae ATCC 204508

-

751188

P38158

UniProt

brenda

Saccharomyces cerevisiae ATCC 204508

-

751188

P53341

SwissProt

brenda

Schizosaccharomyces pombe

-

393278

-

-

brenda

Schizosaccharomyces pombe

-

661611

Q9C0Y4

Uniprot

brenda

Solanum tuberosum

-

393288

-

-

brenda

Solanum tuberosum

gene MAL2w, enzyme MAL2

657123

-

-

brenda

Zea mays

-

708265

-

-

brenda

Zea mays

L. var. saccharata

393282

-

-

brenda