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diagnostics
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the neutral alpha-glucosidase might be a good epididymal marker
agriculture
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possilbe target in mite control
agriculture
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possilbe target in mite control
agriculture
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possilbe target in mite control
agriculture
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possilbe target in mite control
agriculture
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possilbe target in mite control
agriculture
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possilbe target in mite control
agriculture
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possilbe target in mite control
agriculture
Caloglyphus redickorzevi
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possilbe target in mite control
agriculture
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possilbe target in mite control
biotechnology
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expression of the enzyme in rice plants can transduce enhanced resistance against sheath blight pathogen Rhizoctonia solani by inactivation of the RS toxin
biotechnology
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expression of the enzyme in rice plants can transduce enhanced resistance against sheath blight pathogen Rhizoctonia solani by inactivation of the RS toxin
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medicine
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recombinant enzyme is taken up by cultured fibroblasts and skeletal muscle cells from glycogenosis type II patients, and is shown to correct the storage phenotype. Endocytosed enzyme is localised to the lysosome and shows evidence of intracellular processing to a more mature form
medicine
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glycogen storage disease is caused by lysosomal acid alpha-glucosidase deficiency. When injected intravenously, the recombinant enzyme from mouse milk corrects the acid alpha-glucosidase deficiency in heart and skeletal muscle of glycogen storage disease type II knockout mice
medicine
combination of biochemical and structural investigations will give a lot of information for developing enzyme enhancement therapy (EET) for Pompe disease
medicine
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inhibitors from Spiraea cantoniensis could be physiologically useful for treatment of diabetes
medicine
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inhibitors may serve as lead to develop drugs for treatment of type 2 diabetes
medicine
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inhibitors of alpha-glucosidase are promising candidates for the development of antitype II diabetics and anti-AIDS drugs
medicine
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inhibitors of alpha-glucosidase are promising candidates for the development of antitype II diabetics and anti-AIDS drugs
medicine
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one therapeutic approach for decreasing postprandial hyperglycemia is to retard absorption of glucose by inhibition of alpha-glucosidase. Bromophenols of Grateloupia elliptica have potential as natural nutraceuticals to prevent diabetes mellitus because of their high alpha-glucosidase inhibitory activity
medicine
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one therapeutic approach for decreasing postprandial hyperglycemia is to retard absorption of glucose by inhibition of alpha-glucosidase. Bromophenols of Grateloupia elliptica have potential as natural nutraceuticals to prevent diabetes mellitus because of their high alpha-glucosidase inhibitory activity
medicine
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one therapeutic approach for decreasing postprandial hyperglycemia is to retard absorption of glucose by inhibition of alpha-glucosidase. Bromophenols of Grateloupia elliptica have potential as natural nutraceuticals to prevent diabetes mellitus because of their high alpha-glucosidase inhibitory activity
medicine
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enzyme inhibition as therapeutic target for diabetes, in cancer, viral infections and in lysosomal storage diseases
medicine
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potential target for antidiabetic therapy
medicine
potential treatment for Pompe disease
medicine
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target for therapy of type 2 diabetes, antitumor activites, antiviral activites
medicine
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target for therapy of type 2 diabetes, antitumor activites, antiviral activites
medicine
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target for therapy of type 2 diabetes, antitumor activites, antiviral activites
medicine
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target for therapy of type 2 diabetes, antitumor activites, antiviral activites
medicine
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target for therapy of type 2 diabetes, antitumor activites, antiviral activites
medicine
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target for therapy of type 2 diabetes, antitumor activites, antiviral activites
medicine
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target for therapy of type 2 diabetes, antitumor activites, antiviral activites
medicine
target for therapy of type 2 diabetes, antitumor activites, antiviral activites
medicine
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therapeutic target for type II diabetes
medicine
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the enzyme can serve as therapeutic target for the treatment of digestive disorders or their sequelae
medicine
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enzyme activity measured at the first month after microsurgical vasoepididymostomy is an early and independent predictor of patency and natural pregnancy
nutrition
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the enzyme together with the enzyme of Brettanomyces lambicus seems to be the key factor in the overattenuation of lambic beer
nutrition
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production of isomaltooligosaccharides
nutrition
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high thermostability of the enzyme permits the transglucosylation reaction at high temperatures, which is beneficial for continous production of oligosaccharides from sucrose
nutrition
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usage in industrial processes to hydrolyze starch, saccharification step
nutrition
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usage in industrial processes to hydrolyze starch, saccharification step
nutrition
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feeding of maltase-glucoamylase null and wild-type mice with starch diets ad libitum and ad limitum. After ad libitum meals, null and wild-type mice have similar increases of blood glucose concentration. At low intakes, null mice have less fractional glucogenesis than wild-type mice. Null mice do not reduce fractional glucogenesis responses to ad libitum intakes demonstrating the dominant role of sucrose-isomaltase activity during full feeding
nutrition
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high thermostability of the enzyme permits the transglucosylation reaction at high temperatures, which is beneficial for continous production of oligosaccharides from sucrose
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nutrition
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usage in industrial processes to hydrolyze starch, saccharification step
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synthesis
the enzyme can be potentially useful for starch hydrolysis as well for the novel synthesis of oligosaccharides in industry
synthesis
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glucose production from maltodextrins employing a thermophilic immobilized cell biocatalyst in a packed-bed reactor, biotransformation of a commercial dextrin mixture at industrial concentrations (3040%, w/v) into glucose at 75°C, achieving up to 98% conversion
synthesis
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immobilization of enzyme within agar-agar support via entrapment. The maximum immobilization efficiency of 82.77% is achieved using 4.0% agar-agar keeping the diameter of beads up to 3.0 mm. Km value of immobilized enzyme increases from 1.717 to 2.117 mM whereas Vmax decreases from 8,411 to 7,450 U/min as compared to free enzyme. The immobilization significantly increases the stability of maltase against various temperatures and immobilized maltase retains 100% of its original activity after 2 h at 50°C, whereas the free maltase only shows 60% residual activity under the same conditions. Entrapped maltase can be reused for up to 12 cycles and retains 50% of activity even after the 5th cycle. Agar entrapped maltase retains 73% of its initial activity even after 2 months when stored at 30°C
synthesis
the transglycosylation activity of the mutant glycosynthase produced from AglA can be used to synthesize arbutin alpha-glucosides. The glycosynthase reaction is very specific and produces a single transglycosylation compound. Therefore, it can be used to generate regiospecific glycosidic bonds
synthesis
the alpha-transglucosidase-producing Geobacillus stearothermophilus as a potential application technique can be successfully used to prepare industrial isomaltooligosaccharides (IMOs)
synthesis
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glucose production from maltodextrins employing a thermophilic immobilized cell biocatalyst in a packed-bed reactor, biotransformation of a commercial dextrin mixture at industrial concentrations (3040%, w/v) into glucose at 75°C, achieving up to 98% conversion
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synthesis
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the enzyme can be potentially useful for starch hydrolysis as well for the novel synthesis of oligosaccharides in industry
-
synthesis
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immobilization of enzyme within agar-agar support via entrapment. The maximum immobilization efficiency of 82.77% is achieved using 4.0% agar-agar keeping the diameter of beads up to 3.0 mm. Km value of immobilized enzyme increases from 1.717 to 2.117 mM whereas Vmax decreases from 8,411 to 7,450 U/min as compared to free enzyme. The immobilization significantly increases the stability of maltase against various temperatures and immobilized maltase retains 100% of its original activity after 2 h at 50°C, whereas the free maltase only shows 60% residual activity under the same conditions. Entrapped maltase can be reused for up to 12 cycles and retains 50% of activity even after the 5th cycle. Agar entrapped maltase retains 73% of its initial activity even after 2 months when stored at 30°C
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synthesis
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the alpha-transglucosidase-producing Geobacillus stearothermophilus as a potential application technique can be successfully used to prepare industrial isomaltooligosaccharides (IMOs)
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