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3.2.1.182: 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase

This is an abbreviated version!
For detailed information about 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, go to the full flat file.

Word Map on EC 3.2.1.182

Reaction

(2R)-4-hydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl beta-D-glucopyranoside
+
H2O
=
2,4-dihydroxy-2H-1,4-benzoxazin-3(4H)-one
+
D-glucose

Synonyms

benzoxazinone-glucoside beta-D-glucosidase, beta-glu, beta-glucosidase, Co-Glu, DIMBOA glucosidase, DIMBOAGlc hydrolase, GDIBOA-glucosidase, LgGLU1, LgGLU2, LgGLU3, LgGLU4, More, SbDhr1, ScGlu, TaGlu1, TaGlu1a, TaGlu1b, TaGlu1c, ZmGlu1

ECTree

     3 Hydrolases
         3.2 Glycosylases
             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
                3.2.1.182 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase

IC50 Value

IC50 Value on EC 3.2.1.182 - 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.032
2-(1H-indol-3-yl)-2,4-dihydro-1H-benzo[d][1,3]oxazine
Rattus norvegicus
-
pH 6.9, 37°C
0.0167
2-(2-butyl-4-chloro-1H-imidazol-5-yl)-2,4-dihydro-1H-benzo[d][1,3]oxazine
Rattus norvegicus
-
pH 6.9, 37°C
0.0216
2-(2-methyl-1H-indol-3-yl)-2,4-dihydro-1H-benzo[d][1,3]oxazine
Rattus norvegicus
-
pH 6.9, 37°C
0.0319
3-(6-chloro-2,4-dihydro-1H-benzo[d][1,3]oxazin-2-yl)-4H-chromen-4-one
Rattus norvegicus
-
pH 6.9, 37°C
0.0171
4-(2,4-dihydro-1H-benzo[d][1,3]oxazin-2-yl)phenol
Rattus norvegicus
-
pH 6.9, 37°C
0.0115
4-(7-chloro-2,4-dihydro-1H-benzo[d][1,3]oxazin-2-yl)phenol
Rattus norvegicus
-
pH 6.9, 37°C
0.0278
6-chloro-2-(2-phenyl-1H-indol-3-yl)-2,4-dihydro-1H-benzo[d][1,3]oxazine
Rattus norvegicus
-
pH 6.9, 37°C
0.0238
6-methyl-2-(2-methyl-1H-indol-3-yl)-2,4-dihydro-1H-benzo[d][1,3]oxazine
Rattus norvegicus
-
pH 6.9, 37°C
0.0205
6-methyl-2-(2-phenyl-1H-indol-3-yl)-2,4-dihydro-1H-benzo[d][1,3]oxazine
Rattus norvegicus
-
pH 6.9, 37°C
0.0277
7-chloro-2-(1H-indol-3-yl)-2,4-dihydro-1H-benzo[d][1,3]oxazine
Rattus norvegicus
-
pH 6.9, 37°C