3.2.1.180: unsaturated chondroitin disaccharide hydrolase

This is an abbreviated version!
For detailed information about unsaturated chondroitin disaccharide hydrolase, go to the full flat file.

Word Map on EC 3.2.1.180

3.2.1.180

glucuronyl

disaccharides

lyases

streptococcal

glycosaminoglycans

polysaccharide

agalactiae

trimethylation

priming

histone

oncogenesis

trimethylase

Reaction

beta-D-4-deoxy-DELTA4-GlcAp-(1->3)-beta-D-GalNAc6S

N-acetyl-beta-D-galactosamine-6-O-sulfate

Synonyms

Phep_2238, Phep_2649, Phep_2830, SagUGL, SpnUGL, SpyUGL, UGL, unsaturated glucuronyl hydrolase

ECTree

3 Hydrolases

3.2 Glycosylases

3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds

3.2.1.180 unsaturated chondroitin disaccharide hydrolase

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Results	in table
277	AA Sequence
11	Cloned(Commentary)
3	Crystallization (Commentary)
2	Expression
5	General Information
2	IC50 Value
24	Inhibitors
29	kcat/KM [mM/s]
35	KM Value [mM]
6	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
15	Organism
4	Pathway
1	PDB ID
13	pH Optimum
22	Protein Variants
8	Purification (Commentary)
1	Reaction
13	Reference
7	Specific Activity [micromol/min/mg]
96	Substrates and Products (Substrate)
11	Subunits
30	Synonyms
1	Systematic Name
13	Temperature Optimum [°C]
3	Temperature Stability [°C]
33	Turnover Number [1/s]

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Reference on EC 3.2.1.180 - unsaturated chondroitin disaccharide hydrolase

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709026

Maruyama, Y.; Nakamichi, Y.; Itoh, T.; Mikami, B.; Hashimoto, W.; Murata, K.

Substrate spcificity of streptococcal unsaturated glucuronyl hydrolases for sulfated glycosaminoglycan

J. Biol. Chem.

284

18059-18069

2009

Streptococcus pneumoniae (Q8DR77), Streptococcus agalactiae (Q8E372), Streptococcus pyogenes (Q9A0T3), Streptococcus pyogenes M1 GAS SF370 (Q9A0T3), Streptococcus agalactiae NEM316 (Q8E372)

19416976

709164

Nakamichi, Y.; Maruyama, Y.; Mikami, B.; Hashimoto, W.; Murata, K.

Structural determinants in streptococcal unsaturated glucuronyl hydrolase for recognition of glycosaminoglycan sulfate groups

J. Biol. Chem.

286

6262-6271

2011

Streptococcus agalactiae (Q8E372)

21147778

731656

Jongkees, S.A.; Yoo, H.; Withers, S.G.

Mechanistic insights from substrate preference in unsaturated glucuronyl hydrolase

ChemBioChem

124-134

2014

Clostridium perfringens

24227702

732164

Nakamichi, Y.; Mikami, B.; Murata, K.; Hashimoto, W.

Crystal structure of a bacterial unsaturated glucuronyl hydrolase with specificity for heparin

J. Biol. Chem.

289

4787-4797

2014

Bacillus sp. (in: Bacteria), Streptococcus pneumoniae, Streptococcus agalactiae, Streptococcus pyogenes, Pedobacter heparinus (C6XY24), Pedobacter heparinus (C6Y0D8), Pedobacter heparinus (C6Y1N7), Pedobacter heparinus

24403065

754479

Xiong, J.; Xu, D.

Insights into the catalytic mechanism of unsaturated glucuronyl hydrolase of Bacillus sp. GL1

J. Phys. Chem. B

121

931-941

2017

Bacillus sp. GL1

28071912