3.2.1.180: unsaturated chondroitin disaccharide hydrolase

This is an abbreviated version!
For detailed information about unsaturated chondroitin disaccharide hydrolase, go to the full flat file.

Word Map on EC 3.2.1.180

3.2.1.180

glucuronyl

disaccharides

lyases

streptococcal

glycosaminoglycans

polysaccharide

agalactiae

trimethylation

priming

histone

oncogenesis

trimethylase

Reaction

beta-D-4-deoxy-DELTA4-GlcAp-(1->3)-beta-D-GalNAc6S

N-acetyl-beta-D-galactosamine-6-O-sulfate

Synonyms

Phep_2238, Phep_2649, Phep_2830, SagUGL, SpnUGL, SpyUGL, UGL, unsaturated glucuronyl hydrolase

ECTree

3 Hydrolases

3.2 Glycosylases

3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds

3.2.1.180 unsaturated chondroitin disaccharide hydrolase

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Results	in table
277	AA Sequence
11	Cloned(Commentary)
3	Crystallization (Commentary)
2	Expression
5	General Information
2	IC50 Value
24	Inhibitors
29	kcat/KM [mM/s]
35	KM Value [mM]
6	Molecular Weight [Da]
7	Natural Substrates/ Products (Substrates)
15	Organism
4	Pathway
1	PDB ID
13	pH Optimum
22	Protein Variants
8	Purification (Commentary)
1	Reaction
13	Reference
7	Specific Activity [micromol/min/mg]
96	Substrates and Products (Substrate)
11	Subunits
30	Synonyms
1	Systematic Name
13	Temperature Optimum [°C]
3	Temperature Stability [°C]
33	Turnover Number [1/s]

KCat KM Value

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KCat KM Value on EC 3.2.1.180 - unsaturated chondroitin disaccharide hydrolase

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0.55

2,4,6-trichlorophenyl 4-deoxy-alpha-L-threo-hex-4-enopyranosiduronic acid

Clostridium perfringens

pH 6.6, 37°C

731656

0.9

2,4-dinitrophenyl 4-deoxy-alpha-L-threo-hex-4-enopyranosiduronic acid

Clostridium perfringens

pH 6.6, 37°C

731656

1.1

2,5-dinitrophenyl 4-deoxy-alpha-L-threo-hex-4-enopyranosiduronic acid

Clostridium perfringens

pH 6.6, 37°C

731656

0.02

2-(acetylamino)-2-deoxy-3-O-(4-deoxy-alpha-L-threo-hex-4-enopyranuronosyl)-4-O-sulfo-D-galactopyranose

Clostridium perfringens

pH 6.6, 37°C

731656

2-(acetylamino)-2-deoxy-3-O-(4-deoxy-alpha-L-threo-hex-4-enopyranuronosyl)-6-O-sulfo-D-galactopyranose

Clostridium perfringens

pH 6.6, 37°C

731656

2.8

2-(acetylamino)-2-deoxy-3-O-(4-deoxy-alpha-L-threo-hex-4-enopyranuronosyl)-D-galactopyranose

Clostridium perfringens

pH 6.6, 37°C

731656

2-deoxy-4-O-(4-deoxy-alpha-L-threo-hex-4-enopyranuronosyl)-2-(sulfoamino)-D-glucopyranose

Clostridium perfringens

pH 6.6, 37°C

731656

3-nitrophenyl 4-deoxy-alpha-L-threo-hex-4-enopyranosiduronic acid

Clostridium perfringens

pH 6.6, 37°C

731656

4.6

4-chlorophenyl 4-deoxy-alpha-L-threo-hex-4-enopyranosiduronic acid

Clostridium perfringens

pH 6.6, 37°C

731656

0.000044

4-deoxy-alpha-L-threo-hex-4-enopyranuronosyl fluoride

Clostridium perfringens

pH 6.6, 37°C

731656

7.9

4-nitrophenyl 4-deoxy-alpha-L-threo-hex-4-enopyranosiduronic acid

Clostridium perfringens

pH 6.6, 37°C

731656

3.7

4-tert-butylphenyl 4-deoxy-alpha-L-threo-hex-4-enopyranosiduronic acid

Clostridium perfringens

pH 6.6, 37°C

731656

2.1

benzyl 4-deoxy-alpha-L-threo-hex-4-enopyranosiduronic acid

Clostridium perfringens

pH 6.6, 37°C

731656

2.12 - 10.7

beta-D-4-deoxy-DELTA4,5-GlcAp-(1->3)-beta-D-GalNAc

4 entries

1.63 - 130

beta-D-4-deoxy-DELTA4,5-GlcAp-(1->3)-beta-D-GalNAc6S

5 entries

0.086 - 2

DELTAGlcUA-beta-(1->4)-GlcN2S

6 entries

1.3

phenyl 4-deoxy-alpha-L-threo-hex-4-enopyranosiduronic acid

Clostridium perfringens

pH 6.6, 37°C

731656