3.2.1.17: lysozyme This is an abbreviated version! For detailed information about lysozyme, go to the full flat file .
Reaction
N,N',N'',N'''-tetraacetylchitotetraose +
H2O =
N,N',N''-triacetylchitotriose +
N-acetyl-D-glucosamine
Synonyms 1,4-beta-N-acetylmuramidase, 1,4-beta-N-acetylmuramidase 1, 1,4-beta-N-acetylmuramidase A/C, 1,4-beta-N-acetylmuramidase M1, 1,4-beta-N-acetylmuramoylhydrolase, 1,4-N-acetylmuramidase, abLysI, AcmB, ASTL, Autolysin, BA-lysozyme, c-type lysozyme, CCLys-g, CFL, chicken-type lysozyme, cLys3, CP-1 lysin, CP-7 lysin, CP-9 lysin, CPL, DEL-I, DEL-II, DEL-III, destabilase-lysozyme, EGL, Egyptian goose egg-white lysozyme, Egyptian goose lysozyme, endolysin, EQL, equine lysozyme, fOg44 endolysin, g-lysozyme, g-type lysozyme, GEWL, globulin G, globulin G1, goose type lysozyme, Goose-type lysozyme, gp144, gp36C, GSTL, HEWL, HLysG2, hLYZ, HLZ, i-type lysozyme, iLys, iLys2, invertebrate lysozyme, invertebrate type lysozyme, L-7001, LAL, lambda lysozyme, Late protein gp15, Lys-rich lysozyme 2, lysC, LYSC-1, LysG, LysgaY, LysGL, lysi1, lysi2, Lysis protein, Lysosyme, lysozym, Lysozyme, lysozyme 1, lysozyme 1 precursor, lysozyme A, lysozyme B, lysozyme c, lysozyme c-1, lysozyme g, lysozyme g-like 2, lysozyme SP0987, lysozyme-g, LYZ, LYZ2, M1L, Mdl1, MdL2, mlD-Ds1, mlD-Ds2, mlD-Ds3, MLL-A, MLL-B, mucopeptide glucohydrolase, mucopeptide N-acetylmuramic acid hydrolase, mucopeptide N-acetylmuramoylhydrolase, muramidase, mutanolysin, MV1 lysin, N,O-diacetylmuramidase, N-acetylglucosaminidase autolysin, N-acetylmuramic hydrolase, N-acetylmuramide glycanhydrolase, n-SalC, n-SalG, OEL, OHLysG1, OHLysG2, OHLysG3, Outer wedge of baseplate protein, P13, PALysG, Peptidoglycan hydrolase, peptidoglycan n-acetylmuramic hydrolase, phage-type like lysozyme, phiKZ endolysin, Ply3626, PR1-lysozyme, Protein gp17, Protein gp19, Protein Gp25, Protein Gp5, Protein gp54, Protein gpK, SalG, SjLys, SmLysC, SSTL A, SSTL B, T4 lysozyme, T4L, TJL, transglycosylase, VpLYZ, WGL, wood duck lysozyme
ECTree
Natural Substrates Products
Natural Substrates Products on EC 3.2.1.17 - lysozyme
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cell wall of Micrococcus lysodeikticus + H2O
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additional information
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peptidoglycan + H2O
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peptidoglycan + H2O
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peptidoglycan + H2O
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peptidoglycan + H2O
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peptidoglycan + H2O
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peptidoglycan + H2O
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the enzyme cleaves the beta-(1,4)-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine of bacterial cell wall peptidoglycans
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peptidoglycan + H2O
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peptidoglycan + H2O
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peptidoglycan + H2O
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peptidoglycan + H2O
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anti-tumor activity
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peptidoglycan + H2O
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involvement in host defence
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peptidoglycan + H2O
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anti-metastatic activity
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peptidoglycan + H2O
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peptidoglycan + H2O
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peptidoglycan + H2O
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digestive enzyme
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peptidoglycan + H2O
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peptidoglycan + H2O
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peptidoglycan + H2O
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Tequatrovirus T4
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cell lysis from within, at the end of latent period, cell lysis from without, at the beginning of infection
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the enzyme exhibits bacteriolytic activity against Escherichia coli, Aeromonas hydrophila, Staphyloccocus aureus, Bacillus subtilis, Streptococcus sp. and Staphylococcus epidermidis
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the enzyme exhibits bacteriolytic activity against Escherichia coli, Aeromonas hydrophila, Staphyloccocus aureus, Bacillus subtilis, Streptococcus sp. and Staphylococcus epidermidis
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antimicrobial activities of lysozyme derivatives are tested against Staphylococcus aureus ATCC 121002 and Escherichia coli ATCC 29998, as gram-positive and gram-negative representatives, respectively. The enzyme is activa against Staphylococcus aureus, but only poorly against Escherichia coli, overview
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dry-heated lysozyme has increased activity against Escherichia coli membranes compared to native lysozyme, overview. The latter only delays bacterial growth, while dry-heated lysozyme causes an early-stage population decrease. Escherichia coli K-12 strain MG1655 Ivy::Cm, which lacks the periplasmic lysozyme inhibitor Ivy, is utilized
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the enzyme shows antibacterial activity by growth inhibition of a target organism Planococcus citreus
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the destabilase-lysozyme is a bifunctional enzyme, which combines isopeptidase and lysozyme activities
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the destabilase-lysozyme is a bifunctional enzyme, which combines isopeptidase and lysozyme activities
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additional information
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the destabilase-lysozyme is a bifunctional enzyme, which combines isopeptidase and lysozyme activities
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additional information
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lysozyme and its derived peptides are able to bind biotin-labeled pUC19 plasmid DNA. The nonpeptide RAWVAWRNR, amino acids 107-115 of lysozyme, binds DNA with a KD value comparable to histones. Binding results in conformational changes. Lysozyme may represent part of the innate immune system with a very broad protective spectrum
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additional information
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lysozyme and its derived peptides are able to bind biotin-labeled pUC19 plasmid DNA. The nonpeptide RAWVAWRNR, amino acids 107-115 of lysozyme, binds DNA with a KD value comparable to histones. Binding results in conformational changes. Lysozyme may represent part of the innate immune system with a very broad protective spectrum
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recombinant CC-Lys-g produced in Escherichia coli expression system exhibits significant lytic activity against Gram-positive Micrococcus lysodeikticus and Gram-negative Aeromonas hydrophila
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recombinant CC-Lys-g produced in Escherichia coli expression system exhibits significant lytic activity against Gram-positive Micrococcus lysodeikticus and Gram-negative Aeromonas hydrophila
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AcmB expression is modulated during cell growth, AcmB is not involved in cell separation but contributes to cellular autolysis
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AcmB expression is modulated during cell growth, AcmB is not involved in cell separation but contributes to cellular autolysis
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LycGL may be involved in antibacterial immune response activated by bacterial vaccine as an accute-phase molecule
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recombinant enzyme displays inhibitory activity against Gram-negative and Gram-positive bacteria
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comparison of the lytic activities of three recombinant g-type lysozyme isozymes, OHLysG1, OHLysG2 and OHLysG3 against Aeromonas hydrophila, Aeromonas sobria, Vibrio fluvialis, Micrococcus lysodeikticus and Escherichia coli, overview
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enzyme exhibits potent lytic activities against fish pathogens
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enzyme exhibits potent lytic activities against fish pathogens
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the recombinant enzyme displays the lytic activity of g-type lysozyme with other organisms against Micrococcus lysodikicus
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the recombinant enzyme displays the lytic activity of g-type lysozyme with other organisms against Micrococcus lysodikicus
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enzyme lyses specifically Thermus aquaticus cells, with 79% activity on Thermus fhermophilus HB8 and 76% activity on Thermus filífformis
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Thermus virus IN93 phiIN93
enzyme lyses specifically Thermus aquaticus cells, with 79% activity on Thermus fhermophilus HB8 and 76% activity on Thermus filífformis
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additional information
additional information
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Phikzvirus phiKZ
cleaves the glycosidic linkage between N-acetylmuramoyl and N-acetylglucosaminyl residues
formation of a 1,6-anhydromuramoyl product
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