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3.2.1.147: thioglucosidase

This is an abbreviated version!
For detailed information about thioglucosidase, go to the full flat file.

Word Map on EC 3.2.1.147

Reaction

A thioglucoside
+
H2O
=
a sugar
 +
a thiol

Synonyms

ArMy2, AtBGLU37, AtBGLU38, atypical myrosinase, beta-glucosidase 26, peroxisomal, beta-glucosidase 37, beta-glucosidase 38, beta-thioglucosidase, beta-thioglucosidase glucohydrolase, beta-thioglucoside glucohydrolase, beta-thioglucoside glucohydrolase,, BGLU26, CpTGG1, CpTGG2, EC 3.2.3.1, glucosidase, thio-, glucosinolase, More, MYR, MYR II, MYR1 myrosinase, Myr1.Bn1, Myr2.Bn1, MYRc, MYRI, MYRII, myrosin, myrosinase, myrosinase 1, myrosinase 2, myrosinase A, myrosinase B, PEN2, PYK10 myrosinase, sinigrase, sinigrinase, sinigrinase 1, sinigrinase 2, TGG, TGG1, TGG2, TGG4, TGG5, Thioglucosidase, thioglucosidase 1, thioglucosidase 2, thioglucoside glucohydrolase, thioglucoside glucohydrolase 1, thioglycosidase, WjMYR

ECTree

     3 Hydrolases
         3.2 Glycosylases
             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
                3.2.1.147 thioglucosidase

Disease

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Disease on EC 3.2.1.147 - thioglucosidase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Astrocytoma
Rapha Myr®, a Blend of Sulforaphane and Myrosinase, Exerts Antitumor and Anoikis-Sensitizing Effects on Human Astrocytoma Cells Modulating Sirtuins and DNA Methylation.
Carcinogenesis
Apoptosis as a Mechanism of the Cancer Chemopreventive Activity of Glucosinolates: a Review
Preclinical and clinical evaluation of sulforaphane for chemoprevention in the breast.
Carcinoma, Hepatocellular
Glucosinolate-Enriched Fractions from Maca (Lepidium meyenii) Exert Myrosinase-Dependent Cytotoxic Effects against HepG2/C3A and HT29 Tumor Cell Lines.
Cerebral Palsy
Toxicity of Glucosinolate Degradation Products from Brassica napus Seed Meal Toward Aphanomyces euteiches f. sp. pisi.
Colitis
Lightly Cooked Broccoli Is as Effective as Raw Broccoli in Mitigating Dextran Sulfate Sodium-Induced Colitis in Mice.
Colonic Neoplasms
Glucosinolate-Enriched Fractions from Maca (Lepidium meyenii) Exert Myrosinase-Dependent Cytotoxic Effects against HepG2/C3A and HT29 Tumor Cell Lines.
Myrosinase Hydrolysates of Brassica oleraceae L. Var. italica Reduce the Risk of Colon Cancer.
Colorectal Neoplasms
Engineered commensal microbes for diet-mediated colorectal-cancer chemoprevention.
Inhibition of dimethylhydrazine-induced aberrant crypt foci and induction of apoptosis in rat colon following oral administration of the glucosinolate sinigrin.
Cysts
Effects of intact glucosinolates and products produced from glucosinolates in myrosinase-catalyzed hydrolysis on the potato cyst nematode (Globodera rostochiensis Cv. Woll).
Encephalomyelitis
Protective role of (RS )-glucoraphanin bioactivated with myrosinase in an experimental model of multiple sclerosis.
The protective effects of bioactive (RS)-glucoraphanin on the permeability of the mice blood-brain barrier following experimental autoimmune encephalomyelitis.
Encephalomyelitis, Autoimmune, Experimental
Protective role of (RS )-glucoraphanin bioactivated with myrosinase in an experimental model of multiple sclerosis.
The protective effects of bioactive (RS)-glucoraphanin on the permeability of the mice blood-brain barrier following experimental autoimmune encephalomyelitis.
Infections
Glucosinolate profile and Myrosinase gene expression are modulated upon Plasmodiophora brassicae infection in cabbage.
The myrosinase-glucosinolate system in the interaction between Leptosphaeria maculans and Brassica napus.
Toxicity of Glucosinolate Degradation Products from Brassica napus Seed Meal Toward Aphanomyces euteiches f. sp. pisi.
Multiple Sclerosis
Protective role of (RS )-glucoraphanin bioactivated with myrosinase in an experimental model of multiple sclerosis.
The protective effects of bioactive (RS)-glucoraphanin on the permeability of the mice blood-brain barrier following experimental autoimmune encephalomyelitis.
Neoplasms
Apoptosis as a Mechanism of the Cancer Chemopreventive Activity of Glucosinolates: a Review
Characterization of a novel ?-thioglucosidase CpTGG1 in Carica papaya and its substrate-dependent and ascorbic acid-independent O-?-glucosidase activity.
Identification, synthesis, and enzymology of non-natural glucosinolate chemopreventive candidates.
Induction of Apoptosis and Cytotoxicity by Raphasatin in Human Breast Adenocarcinoma MCF-7 Cells.
Kaiware Daikon (Raphanus sativus L.) extract: a naturally multipotent chemopreventive agent.
Myrosinase Hydrolysates of Brassica oleraceae L. Var. italica Reduce the Risk of Colon Cancer.
Relationship of climate and genotype to seasonal variation in the glucosinolate-myrosinase system. II. Myrosinase activity in ten cultivars of Brassica oleracea grown in fall and spring seasons.
Neuroblastoma
Moringin from Moringa Oleifera Seeds Inhibits Growth, Arrests Cell-Cycle, and Induces Apoptosis of SH-SY5Y Human Neuroblastoma Cells through the Modulation of NF-?B and Apoptotic Related Factors.
Neuroinflammatory Diseases
Moringin activates Wnt canonical pathway by inhibiting GSK3? in a mouse model of experimental autoimmune encephalomyelitis.
Parkinson Disease
Anti-inflammatory and anti-apoptotic effects of (RS)-glucoraphanin bioactivated with myrosinase in murine sub-acute and acute MPTP-induced Parkinson's disease.
The Isothiocyanate Isolated from Moringa oleifera Shows Potent Anti-Inflammatory Activity in the Treatment of Murine Subacute Parkinson's Disease.
Spinal Cord Injuries
RS-Glucoraphanin bioactivated with myrosinase treatment counteracts proinflammatory cascade and apoptosis associated to spinal cord injury in an experimental mouse model.