3.2.1.144: 3-deoxyoctulosonase
This is an abbreviated version!
For detailed information about 3-deoxyoctulosonase, go to the full flat file.
Reaction
Synonyms
3-deoxy-D-manno-oct-2-ulosonic acid alpha-ketoside hydrolase, 3-deoxy-octulo-sonase, alpha-Kdo-ase
ECTree
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Natural Substrates Products on EC 3.2.1.144 - 3-deoxyoctulosonase
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REACTION DIAGRAM
re-lipopolysaccharide + H2O
3-deoxy-D-manno-octulosonic acid + lipopolysaccharide
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additional information
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the recombinant alpha-Kdo-ase effectively hydrolyzes the alpha-ketoside in the core-oligosaccharide of the structurally defined lipopolysaccharide (LPS), Re-LPS (Kdo2-lipid A) from Salmonella minnesota strain R595 and Escherichia coli strain D31m4, while Rd-LPS from Salmonella minnesota strain R7, that contains an extra outer core phosphorylated heptose, is only slowly hydrolyzed. The complex type LPS from Neisseria meningitides strains A1 and M992 that contain extra 5-6 sugar units at the outer core are refractory to recombinnat alpha-Kdo-ase
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