3.2.1.123: endoglycosylceramidase

This is an abbreviated version!
For detailed information about endoglycosylceramidase, go to the full flat file.

Reaction

Synonyms

ceramidase, endoglycosyl-, ceramide glycanase, EGALC, EGC, EGCase, EGCase I, EGCase II, EGCase III, EGCII, EGCrP1, EGCrP2, endo-glycoceramidase II, endogalactosylceramidase, endoglycoceramidase, endoglycoceramidase I, endoglycoceramidase II, endoglycoceramidase-related protein, glycosyl-N-acetyl-sphingosine 1,1-beta-D-glucanohydrolase, oligogalactosyl-N-acylsphingosine 1,1'-beta-galactohydrolase

ECTree

     3 Hydrolases

         3.2 Glycosylases

             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds

                3.2.1.123 endoglycosylceramidase

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Results	in table
28	Activating Compound
62	AA Sequence
6	Application
1	CAS Registry Number
14	Cloned(Commentary)
3	Crystallization (Commentary)
5	General Stability
32	Inhibitors
11	kcat/KM [mM/s]
3	Ki Value [mM]
27	KM Value [mM]
6	Localization
5	Metals/Ions
16	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
66	Organism
1	Oxidation Stability
11	PDB ID
25	pH Optimum
3	pH Range
4	pH Stability
6	pI Value
1	Posttranslational Modification
39	Protein Variants
16	Purification (Commentary)
1	Reaction
3	Reaction Type
56	Reference
13	Source Tissue
24	Specific Activity [micromol/min/mg]
3	Storage Stability
239	Substrates and Products (Substrate)
12	Subunits
75	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
1	Temperature Range [°C]
4	Temperature Stability [°C]
14	Turnover Number [1/s]

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TURNOVER NUMBER [1/s]

SUBSTRATE

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

8.8

4-methylumbelliferyl beta-D-glucoside

Cryptococcus neoformans

-

isoform EGCrP2, at pH 6.0 and 37°C

732178

13.8

4-nitrophenyl-beta-D-glucoside

Cryptococcus neoformans

-

isoform EGCrP2, at pH 6.0 and 37°C

732178

0.088 - 10.5

beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-(alpha-Neu5Ac-(2->3))-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-ceramide

2 entries

0.0383 - 0.53

C6-7-nitro-2,1,3-benzoxadiazole-glucosylceramide

2 entries

0.12

D-erythro-dihydrosphingosine

Rhodococcus sp.

-

-

680770

0.07

D-erythro-sphingosine

Rhodococcus sp.

-

-

680770

13.3

Galbeta1-6Galbeta1-6Galbeta1-1'ceramide

Rhodococcus equi

-

-

680753

0.069 - 85

ganglioside Gb3Cer

2 entries

5.7 - 120

ganglioside GM1a

2 entries

21.9

resorufin

Cryptococcus neoformans

-

isoform EGCrP2, at pH 6.0 and 37°C

732178

0.088

beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-(alpha-Neu5Ac-(2->3))-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-ceramide

Rhodococcus sp. M-777

O33853

pH 6.0, 37°C

751102

10.5

beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-(alpha-Neu5Ac-(2->3))-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-ceramide

Rhodococcus equi

A0A3S5YBC7

pH 6.0, 37°C

751102

0.0383

C6-7-nitro-2,1,3-benzoxadiazole-glucosylceramide

Cryptococcus neoformans

-

isoform EGCrP1, at pH 6.0 and 37°C

732178

0.53

C6-7-nitro-2,1,3-benzoxadiazole-glucosylceramide

Cryptococcus neoformans

-

isoform EGCrP2, at pH 6.0 and 37°C

732178

0.069

ganglioside Gb3Cer

Rhodococcus equi

-

isoform EHCase II, pH 5.5 and 37°C

732295

85

ganglioside Gb3Cer

Rhodococcus equi

-

isoform EHCase I, pH 5.5 and 37°C

732295

5.7

ganglioside GM1a

Rhodococcus equi

-

isoform EHCase II, pH 5.5 and 37°C

732295

120

ganglioside GM1a

Rhodococcus equi

-

isoform EHCase I, pH 5.5 and 37°C

732295