3.2.1.123: endoglycosylceramidase

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For detailed information about endoglycosylceramidase, go to the full flat file.

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Synonyms

ceramidase, endoglycosyl-, ceramide glycanase, EGALC, EGC, EGCase, EGCase I, EGCase II, EGCase III, EGCII, EGCrP1, EGCrP2, endo-glycoceramidase II, endogalactosylceramidase, endoglycoceramidase, endoglycoceramidase I, endoglycoceramidase II, endoglycoceramidase-related protein, glycosyl-N-acetyl-sphingosine 1,1-beta-D-glucanohydrolase, oligogalactosyl-N-acylsphingosine 1,1'-beta-galactohydrolase

ECTree

     3 Hydrolases

         3.2 Glycosylases

             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds

                3.2.1.123 endoglycosylceramidase

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Results	in table
28	Activating Compound
62	AA Sequence
6	Application
1	CAS Registry Number
14	Cloned(Commentary)
3	Crystallization (Commentary)
5	General Stability
32	Inhibitors
11	kcat/KM [mM/s]
3	Ki Value [mM]
27	KM Value [mM]
6	Localization
5	Metals/Ions
16	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
66	Organism
1	Oxidation Stability
11	PDB ID
25	pH Optimum
3	pH Range
4	pH Stability
6	pI Value
1	Posttranslational Modification
39	Protein Variants
16	Purification (Commentary)
1	Reaction
3	Reaction Type
56	Reference
13	Source Tissue
24	Specific Activity [micromol/min/mg]
3	Storage Stability
239	Substrates and Products (Substrate)
12	Subunits
75	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
1	Temperature Range [°C]
4	Temperature Stability [°C]
14	Turnover Number [1/s]

Systematic Name

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Systematic Name on EC 3.2.1.123 - endoglycosylceramidase

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SYSTEMATIC NAME

IUBMB Comments

oligoglycosylglucosyl-(1<->1)-ceramide glycohydrolase

An enzyme from Rhodococcus sp. that degrades various acidic and neutral glycosphingolipids to oligosaccharides and ceramides, by cleaving a glucosyl bond. Does not act on monoglycosylceramides. cf. EC 3.2.1.62 glycosylceramidase.