3.2.1.123: endoglycosylceramidase
This is an abbreviated version!
For detailed information about endoglycosylceramidase, go to the full flat file.
Word Map on EC 3.2.1.123
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3.2.1.123
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glycosphingolipids
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gangliosides
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cgases
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n-deacylase
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yamagata
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ganglio
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macrobdella
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decora
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gm1a
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diagnostics
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analysis
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drug development
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medicine
- 3.2.1.123
- glycosphingolipids
- gangliosides
- cgases
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n-deacylase
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yamagata
-
ganglio
-
macrobdella
- decora
- gm1a
- diagnostics
- analysis
- drug development
- medicine
Reaction
Synonyms
ceramidase, endoglycosyl-, ceramide glycanase, EGALC, EGC, EGCase, EGCase I, EGCase II, EGCase III, EGCII, EGCrP1, EGCrP2, endo-glycoceramidase II, endogalactosylceramidase, endoglycoceramidase, endoglycoceramidase I, endoglycoceramidase II, endoglycoceramidase-related protein, glycosyl-N-acetyl-sphingosine 1,1-beta-D-glucanohydrolase, oligogalactosyl-N-acylsphingosine 1,1'-beta-galactohydrolase
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Natural Substrates Products
Natural Substrates Products on EC 3.2.1.123 - endoglycosylceramidase
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REACTION DIAGRAM
oligoglycosylglucosyl-(1<->1)-ceramide + H2O
ceramide + oligoglycosylglucose
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enzyme destroys the cholera toxin receptor GM1 on the cell surface of HELA cells and therefore reduces the amount of cholera toxin attached to the cells
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additional information
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reduces glycosphingolipid levels in HL60 cells
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additional information
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removes glycosphinolipid-sugar chains from the cell surface of living cells
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additional information
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reduces ganglioside content in membrane fractions and intact cells of A431 cells
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