3.2.1.123: endoglycosylceramidase

This is an abbreviated version!
For detailed information about endoglycosylceramidase, go to the full flat file.

Word Map on EC 3.2.1.123

3.2.1.123

glycosphingolipids

gangliosides

cgases

n-deacylase

yamagata

ganglio

macrobdella

decora

gm1a

diagnostics

analysis

drug development

medicine

Reaction

Synonyms

ceramidase, endoglycosyl-, ceramide glycanase, EGALC, EGC, EGCase, EGCase I, EGCase II, EGCase III, EGCII, EGCrP1, EGCrP2, endo-glycoceramidase II, endogalactosylceramidase, endoglycoceramidase, endoglycoceramidase I, endoglycoceramidase II, endoglycoceramidase-related protein, glycosyl-N-acetyl-sphingosine 1,1-beta-D-glucanohydrolase, oligogalactosyl-N-acylsphingosine 1,1'-beta-galactohydrolase

ECTree

3 Hydrolases

3.2 Glycosylases

3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds

3.2.1.123 endoglycosylceramidase

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Results	in table
28	Activating Compound
62	AA Sequence
6	Application
1	CAS Registry Number
14	Cloned(Commentary)
3	Crystallization (Commentary)
5	General Stability
32	Inhibitors
11	kcat/KM [mM/s]
3	Ki Value [mM]
27	KM Value [mM]
6	Localization
5	Metals/Ions
16	Molecular Weight [Da]
5	Natural Substrates/ Products (Substrates)
66	Organism
1	Oxidation Stability
11	PDB ID
25	pH Optimum
3	pH Range
4	pH Stability
6	pI Value
1	Posttranslational Modification
39	Protein Variants
16	Purification (Commentary)
1	Reaction
3	Reaction Type
56	Reference
13	Source Tissue
24	Specific Activity [micromol/min/mg]
3	Storage Stability
239	Substrates and Products (Substrate)
12	Subunits
75	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
1	Temperature Range [°C]
4	Temperature Stability [°C]
14	Turnover Number [1/s]

KM Value

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KM Value on EC 3.2.1.123 - endoglycosylceramidase

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1.4 - 2.9

2-N-hexadecanoylamino-4-nitrophenyl-O-beta-lactoside

2 entries

0.34

4-methylumbelliferyl beta-D-glucoside

Cryptococcus neoformans

isoform EGCrP2, at pH 6.0 and 37°C

732178

0.817

4-nitrophenyl-beta-D-glucoside

Cryptococcus neoformans

isoform EGCrP2, at pH 6.0 and 37°C

732178

0.23 - 0.25

beta-D-Gal-(1->3)-beta-D-GalNAc-(1->4)-(alpha-Neu5Ac-(2->3))-beta-D-Gal-(1->4)-beta-D-Glc-(1<->1')-ceramide

2 entries

0.0058 - 0.0384

C6-7-nitro-2,1,3-benzoxadiazole-glucosylceramide

2 entries

0.3

D-erythro-dihydrosphingosine

Rhodococcus sp.

680770

0.04

D-erythro-sphingosine

Rhodococcus sp.

680770

0.15 - 0.35

Galbeta(1-3)GalNAcbeta(1-4)(NeuAcalpha(2-3))Galbeta(1-4)Glcbeta(1-1)ceramide

2 entries

0.28 - 16.5

Galbeta(1-3)GalNAcbeta(1-4)(NeuAcalpha(2-8)NeuAcalpha(2-3))Galbeta(1-4)Glcbeta(1-1)ceramide

2 entries

0.1 - 0.5

Galbeta(1-3)GalNAcbeta(1-4)Galbeta(1-4)Glcbeta(1-1)ceramide

5 entries

0.43

Galbeta1-6Galbeta1-6Galbeta1-1'ceramide

Rhodococcus equi

680753

0.047

GalNAcbeta(1-4)Galbeta(1-4)Glcbeta(1-1)ceramide

Rhodococcus sp.

i.e. Gg3Cer from guinea pig erythrocyte cell surface, pH 7, 37°C

646693

0.23 - 0.46

ganglioside Gb3Cer

2 entries

0.4 - 0.43

ganglioside GM1a

2 entries

0.044

NeuAcalpha(2-3)Galbeta(1-4)Glcbeta(1-1)ceramide

Rhodococcus sp.

from horse erythrocyte cell surface, pH 7, 37°C

646693

0.0436

resorufin

Cryptococcus neoformans

isoform EGCrP2, at pH 6.0 and 37°C

732178