3.2.1.118: prunasin beta-glucosidase

This is an abbreviated version!
For detailed information about prunasin beta-glucosidase, go to the full flat file.

Reaction

Synonyms

beta-glucosidase, hydrolase, prunasin, PH I, PH IIa, PH IIb, Ph691, prunasin hydrolase, prunasin hydrolase isozyme I, prunasin hydrolase isozyme IIa, prunasin hydrolase isozyme IIb

ECTree

     3 Hydrolases

         3.2 Glycosylases

             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds

                3.2.1.118 prunasin beta-glucosidase

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Results	in table
13	AA Sequence
2	Application
1	CAS Registry Number
2	Cloned(Commentary)
2	General Information
10	Inhibitors
2	Ki Value [mM]
8	Localization
13	Molecular Weight [Da]
14	Natural Substrates/ Products (Substrates)
16	Organism
4	Pathway
1	pH Optimum
1	pH Range
2	Posttranslational Modification
1	Protein Variants
7	Purification (Commentary)
7	Reaction
1	Reaction Type
15	Reference
30	Source Tissue
5	Specific Activity [micromol/min/mg]
1	Storage Stability
35	Substrates and Products (Substrate)
5	Subunits
14	Synonyms
1	Systematic Name

Natural Substrates Products

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Natural Substrates Products on EC 3.2.1.118 - prunasin beta-glucosidase

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NATURAL SUBSTRATE

NATURAL PRODUCT

REACTION DIAGRAM

ORGANISM

UNIPROT

COMMENTARY
(Substrate)

LITERATURE
(Substrate)

COMMENTARY
(Product)

LITERATURE
(Product)

REVERSIBILITY
r=reversible
ir=irreversible
?=not specified

(R)-prunasin + H2O

D-glucose + mandelonitrile

2 entries

(R)-prunasin + H2O

mandelonitrile + D-glucose

9 entries

prunasin + H2O

D-mandelonitrile + beta-D-glucose

2 entries

(R)-prunasin + H2O

D-glucose + mandelonitrile

Prunus dulcis

-

-

732652

-

-

?

(R)-prunasin + H2O

D-glucose + mandelonitrile

Prunus dulcis

H9ZGE1

the enzyme is involved in the metabolic pathway for the synthesis and catabolism of the cyanogenic glucoside prunasin

751884

-

-

?

(R)-prunasin + H2O

mandelonitrile + D-glucose

Mucor circinelloides

-

-

646657

-

646657

?

(R)-prunasin + H2O

mandelonitrile + D-glucose

Penicillium aurantiogriseum

-

-

646657

-

646657

?

(R)-prunasin + H2O

mandelonitrile + D-glucose

Prunus domestica

-

-

646651

-

646651

?

(R)-prunasin + H2O

mandelonitrile + D-glucose

Prunus serotina

-

involved in cyanogenesis from (R)-amygdalin

646649

-

646649

?

(R)-prunasin + H2O

mandelonitrile + D-glucose

Prunus serotina

-

involved in cyanogenesis from (R)-amygdalin

646650

-

646650

?

(R)-prunasin + H2O

mandelonitrile + D-glucose

Prunus serotina

-

involved in cyanogenesis from (R)-amygdalin

646652

-

646652

?

(R)-prunasin + H2O

mandelonitrile + D-glucose

Prunus serotina

-

involved in cyanogenesis from (R)-amygdalin

646657

-

646657

?

(R)-prunasin + H2O

mandelonitrile + D-glucose

Prunus serotina

-

involved in cyanogenesis from (R)-amygdalin

646659

-

646659

?

(R)-prunasin + H2O

mandelonitrile + D-glucose

Prunus serotina

-

involved in cyanogenesis from (R)-amygdalin

646660

-

646660

?

prunasin + H2O

D-mandelonitrile + beta-D-glucose

Homo sapiens

-

prunasin is taken up in the small intestine and decomposed by beta-glucosidase into glucose and mandelonitrile, which is further hydrolyzed to benzaldehyde and hydrogen cyanide. Amygdalin, the precursor of prunasin, is a toxic component and can cause fatal cyanide poisonings, chronic toxicity, and death

708783

-

-

?

prunasin + H2O

D-mandelonitrile + beta-D-glucose

Prunus dulcis

-

-

706240, 706999

-

-

?