3.2.1.111: 1,3-alpha-L-fucosidase

This is an abbreviated version!
For detailed information about 1,3-alpha-L-fucosidase, go to the full flat file.

Reaction

Synonyms

AfcB, almond emulsin fucosidase I, alpha(1,3/4)-transfucosidase, alpha-1,3/4-L-fucosidase, alpha-L-fucosidase I, alphafuc, BbAfcB, cFase I, core fucosidase I, CpAfc2, fucosidase, 1,3-alpha-L-

ECTree

     3 Hydrolases

         3.2 Glycosylases

             3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds

                3.2.1.111 1,3-alpha-L-fucosidase

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Results	in table
2	Activating Compound
9	AA Sequence
1	CAS Registry Number
5	Cloned(Commentary)
1	General Information
3	General Stability
11	Inhibitors
25	kcat/KM [mM/s]
26	KM Value [mM]
4	Metals/Ions
3	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
10	Organism
8	PDB ID
4	pH Optimum
3	pH Range
2	pH Stability
24	Protein Variants
8	Purification (Commentary)
1	Reaction
1	Reaction Type
10	Reference
3	Source Tissue
3	Specific Activity [micromol/min/mg]
3	Storage Stability
44	Substrates and Products (Substrate)
3	Subunits
18	Synonyms
1	Systematic Name
4	Temperature Optimum [°C]
1	Temperature Range [°C]
2	Temperature Stability [°C]
24	Turnover Number [1/s]

Inhibitors

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Inhibitors on EC 3.2.1.111 - 1,3-alpha-L-fucosidase

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INHIBITOR

ORGANISM

UNIPROT

COMMENTARY

LITERATURE

IMAGE

Co2+

Bifidobacterium bifidum

-

40% residual activity

708607

Cu2+

2 entries

deoxyfuconojirimycin

Elizabethkingia meningoseptica

-

about 15% residual activity at 0.5 mM

751107

Hg2+

Prunus dulcis

-

strong

646567

L-fucose

Prunus dulcis

-

-

646567

malonate

Prunus dulcis

-

above 20 mM

646567

p-chloromercuribenzoate

Elizabethkingia meningoseptica

-

0.5% residual activity at 0.5 mM

751107

SDS

Elizabethkingia meningoseptica

-

0.1% (w/v) SDS almost inactivates the enzyme

751107

Zn2+

Elizabethkingia meningoseptica

-

87% residual activity at 1 mM

751107

additional information

Elizabethkingia meningoseptica

-

not inhibited by EDTA, urea or dithiothreitol

751107

-

Cu2+

Bifidobacterium bifidum

-

complete inactiviation

708607

Cu2+

Elizabethkingia meningoseptica

-

14.6% residual activity at 1 mM

751107