3.2.1.105: 3alpha(S)-strictosidine beta-glucosidase
This is an abbreviated version!
For detailed information about 3alpha(S)-strictosidine beta-glucosidase, go to the full flat file.
Word Map on EC 3.2.1.105
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3.2.1.105
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roseus
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catharanthus
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indole
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jasmonate
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terpenoid
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monoterpenoid
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vinblastine
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vincristine
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secologanin
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hairy
-
jasmonate-responsive
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ap2-domain
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rauvolfia
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tryptamine
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catharanthine
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periwinkle
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vindoline
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ajmaline
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serpentina
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deglucosylation
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jasmonate-induced
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methyl-jasmonate
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10-hydroxylase
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madagascar
-
medicine
-
pharmacology
- 3.2.1.105
- roseus
- catharanthus
- indole
- jasmonate
-
terpenoid
-
monoterpenoid
- vinblastine
- vincristine
- secologanin
-
hairy
-
jasmonate-responsive
-
ap2-domain
- rauvolfia
- tryptamine
-
catharanthine
- periwinkle
- vindoline
- ajmaline
- serpentina
-
deglucosylation
-
jasmonate-induced
-
methyl-jasmonate
-
10-hydroxylase
-
madagascar
- medicine
- pharmacology
Reaction
Synonyms
glucosidase, strictosidine beta-, ORCA3, SBG, SG, SGD, strictosidine beta-D-glucohydrolase, strictosidine beta-D-glucosidase, strictosidine beta-glucosidase, strictosidine glucosidase
ECTree
3.2.1.105 3alpha(S)-strictosidine beta-glucosidaseAdvanced search results
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results (Substrates Products
Substrates Products on EC 3.2.1.105 - 3alpha(S)-strictosidine beta-glucosidase
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SUBSTRATE 
PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
18,19-dihydrostrictosidine + H2O
D-glucose + 18,19-dihydrostrictosidine aglycone
-
-
-
?
5-methylstrictosidine + H2O
D-glucose + 5-methylstrictosidine aglycone
-
-
-
-
?
5alpha-carboxystrictosidine + H2O
D-glucose + 5alpha-carboxystrictosidine aglycone
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-
-
?
6-fluorostrictosidine + H2O
D-glucose + 6-fluorostrictosidine aglycone
-
-
-
-
?
6-methoxystrictosidine + H2O
D-glucose + 6-methoxystrictosidine aglycone
-
-
-
-
?
6-methylstrictosidine + H2O
D-glucose + 6-methylstrictosidine aglycone
-
-
-
-
?
7-fluorostrictosidine + H2O
D-glucose + 7-fluorostrictosidine aglycone
-
-
-
-
?
7-methoxystrictosidine + H2O
D-glucose + 7-methoxystrictosidine aglycone
-
-
-
-
?
7-methylstrictosidine + H2O
D-glucose + 7-methylstrictosidine aglycone
-
-
-
-
?
8-methylstrictosidine + H2O
D-glucose + 8-methylstrictosidine aglycone
-
-
-
-
?
Nbeta-acetylstrictosidine + H2O
D-glucose + Nbeta-acetylstrictosidine aglycone
weak substrate
-
-
?
Nbeta-methylstrictosidine + H2O
D-glucose + Nbeta-methylstrictosidine aglycone
weak substrate
-
-
?
vincoside pent-4-yn-1-yl ester + H2O
D-glucose + vincoside pent-4-yn-1-yl ester aglycone
-
-
-
-
?
strictosidine
?
-
the enzyme may play an important role in steering the monoterpenoid indole alkaloid biosynthesis in a specific direction
-
-
?
strictosidine
?
enzyme in terpenoid indole alkaloid biosynthesis
-
-
?
strictosidine + H2O
D-glucose + strictosidine aglycone
-
-
-
-
?
strictosidine + H2O
D-glucose + strictosidine aglycone
-
-
i.e. hemiacetal
-
?
strictosidine + H2O
D-glucose + strictosidine aglycone
specific substrate
-
-
?
strictosidine + H2O
D-glucose + strictosidine aglycone
-
The structural diversity of monoterpenoid indole alkaloids comes first from the deglucosylation of strictosidine by strictosidine beta-glucosidase. The unstable and versatile aglycone is biochemically converted by mostly uncharacterized enzyme reactions to the Corynanthe, Iboga and Aspidosperma classes of alkaloids such as ajmalicine, catharanthine and tabersonine, respectively
-
-
?
strictosidine + H2O
D-glucose + strictosidine aglycone
-
-
-
?
strictosidine + H2O
D-glucose + strictosidine aglycone
specific substrate
-
-
?
strictosidine + H2O
D-glucose + strictosidine aglycone
-
-
the major intermediate after rearrangement of the strictosidine aglycone is thought to be 21-hydroxyajmalicine
?
additional information
?
-
-
involved In the indole alkaloid biosynthesis by hydrolyzing strictosidine to cathenamine
-
-
?
additional information
?
-
no substrates: strictosidine pentaacetate, vincoside, strictosidine lactam, vincoside lactam, raucafficrine, 1,2-dihydrocafficrine, 1-methyl-1,2-dihydrocarcafficrine, secologanin, loganin, 4-nitrophenylglucoside, arbutin, vanillin-glucoside, isatinoxim-glucoside, prunasin, rhapontin, rutin, sinigrin and zeatin-glucoside
-
-
?
additional information
?
-
-
no substrates: strictosidine pentaacetate, vincoside, strictosidine lactam, vincoside lactam, raucafficrine, 1,2-dihydrocafficrine, 1-methyl-1,2-dihydrocarcafficrine, secologanin, loganin, 4-nitrophenylglucoside, arbutin, vanillin-glucoside, isatinoxim-glucoside, prunasin, rhapontin, rutin, sinigrin and zeatin-glucoside
-
-
?
additional information
?
-
the enzyme does not accept raucaffricine as substrate
-
-
?
additional information
?
-
-
no activity with secologanin, strictosamide or p-nitrophenyl-beta-D-glucopyranoside
-
-
?
