3.12.1.B1: tetrathionate hydrolase
This is an abbreviated version!
For detailed information about tetrathionate hydrolase, go to the full flat file.
Word Map on EC 3.12.1.B1
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3.12.1.B1
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sulfur
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acidithiobacillus
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thiosulfate
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ferrooxidans
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acidophilic
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sulfide
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sulfur-oxidizing
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ferrous
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dissimilatory
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bioleaching
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heterodisulfide
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chemolithoautotrophic
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caldus
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chemolithotrophic
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thermoacidophilic
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thiooxidans
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teth
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iron-grown
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polythionates
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sulfolobales
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analysis
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thermosulfidooxidans
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biogeochemical
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rusticyanin
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metallosphaera
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extremophile
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acidianus
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sulfobacillus
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pqq
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thiobacillus
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biomining
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sedula
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sor
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consortia
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industry
- 3.12.1.B1
- sulfur
- acidithiobacillus
- thiosulfate
- ferrooxidans
-
acidophilic
- sulfide
-
sulfur-oxidizing
-
ferrous
-
dissimilatory
-
bioleaching
-
heterodisulfide
-
chemolithoautotrophic
- caldus
-
chemolithotrophic
-
thermoacidophilic
- thiooxidans
-
teth
-
iron-grown
- polythionates
- sulfolobales
- analysis
- thermosulfidooxidans
-
biogeochemical
- rusticyanin
-
metallosphaera
-
extremophile
-
acidianus
- sulfobacillus
- pqq
-
thiobacillus
-
biomining
- sedula
-
sor
-
consortia
- industry
Reaction
Synonyms
4THase, Af-Tth, Ahos_1670, SH-tth, Teth, tetrathionate hydrolase, Tth1
ECTree
3.12.1.B1 tetrathionate hydrolaseAdvanced search results
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General Information on EC 3.12.1.B1 - tetrathionate hydrolase
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GENERAL INFORMATION 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
malfunction
the DELTAtetH mutant can survive in ferrous medium with an Fe2+ oxidation rate similar to that of the wild-type. For the tetH overexpression strain, the rate is relatively higher than that of the wild type
metabolism
physiological function
additional information
metabolism
the enzyme is a key enzyme in the dissimilatory sulfur oxidation pathway in this bacterium
metabolism
the organism can obtain energy from the oxidation of Fe2+, H2, and sulfur, and various reduced inorganic sulfur compounds (RISCs). Tetrathionate is a key intermediate during RISC oxidation, hydrolyzed by tetrathionate hydrolase (TetH), and used as sole energy source. Genes tetH and doxD2 act synergistically, and doxD2 is considered important in thiosulfate metabolism
metabolism
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the enzyme is involved in tetrathionate metabolism, but also in thiosulfate and elemental sulfur metabolism
metabolism
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the enzyme is involved in tetrathionate metabolism, but also in thiosulfate and elemental sulfur metabolism
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physiological function
under oxygen-sufficient conditions strain oxidizes thiosulfate to tetrathionate, which accumulates in the culture medium. Tetrathionate is then oxidized by tetrathionate hydrolase generating thiosulfate, elemental sulfur, and sulfate as final products. In thiosulfate-grown cultures shifted to oxygen-limiting conditions a massive production of extracellular conspicuous sulfur globules is seen, with concomitant decrease in tetrathionate concentration. Cellular tetrathionate hydrolase activity is negligible in oxygen-limiting conditions, while extracellular activity is high under both conditions
physiological function
the enzyme is a key enzyme in hydrolysis of tetrathionate for usage as sole energy source
physiological function
the enzyme is key enzyme in the dissimilatory sulfur oxidation pathway and catalyzes tetrathionate hydrolysis to generate elemental sulfur, thiosulfate, and sulfate
additional information
the sole cysteine residue, Cys301, of tetrathionate hydrolase from Acidithiobacillus ferrooxidans does neither play a role in enzyme activity nor in subunit assembly
additional information
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the sole cysteine residue, Cys301, of tetrathionate hydrolase from Acidithiobacillus ferrooxidans does neither play a role in enzyme activity nor in subunit assembly
