3.1.8.2: diisopropyl-fluorophosphatase
This is an abbreviated version!
For detailed information about diisopropyl-fluorophosphatase, go to the full flat file.
Word Map on EC 3.1.8.2
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3.1.8.2
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dfpase
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organophosphorus
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dfp
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degradation
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squid
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paraoxonase
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sarin
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phosphotriesterases
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paraoxon
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environmental protection
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loligo
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opaas
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arylesterase
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bioscavenger
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vx
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methylphosphonofluoridate
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medicine
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cyclosarin
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six-bladed
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carbanilate
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udp-glucosyltransferase
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diisopropylphosphorofluoridate
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2.8.2.1
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arylsulfotransferase
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udp-glucuronyltransferase
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2.3.1.5
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analysis
- 3.1.8.2
- dfpase
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organophosphorus
- dfp
- degradation
- squid
- paraoxonase
- sarin
- phosphotriesterases
- paraoxon
- environmental protection
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loligo
-
opaas
- arylesterase
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bioscavenger
- vx
- methylphosphonofluoridate
- medicine
- cyclosarin
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six-bladed
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carbanilate
- udp-glucosyltransferase
- diisopropylphosphorofluoridate
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2.8.2.1
- arylsulfotransferase
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udp-glucuronyltransferase
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2.3.1.5
- analysis
Reaction
Synonyms
DFPase, di-isopropylphosphorofluoridate fluorohydrolase, dialkylfluorophosphatase, diisopropyl fluorophosphatase, diisopropyl phosphorofluoridate hydrolase, diisopropylfluorophosphatase, diisopropylfluorophosphonate dehalogenase, diisopropylphosphofluoridase, EC 3.8.2.1, h-PON1, isopropylphosphorofluoridase, More, OP-hydrolyzing enzyme, OPA anhydrase, OPA anhydrolase, OPAA, OPAA-2, opd, OPH, organophosphate acid anhydrase, organophosphate anhydrolase/prolidase, organophosphorus acid anhydrolase, organophosphorus hydrolase, organophosphorus-hydrolyzing enzyme, paraoxonase 1, phosphotriesterase, PON1, PTES5, RC, regucalcin, senescence marker protein-30, SMP30, somanase, tabunase
ECTree
3.1.8.2 diisopropyl-fluorophosphataseAdvanced search results
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results (Natural Substrates Products
Natural Substrates Products on EC 3.1.8.2 - diisopropyl-fluorophosphatase
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NATURAL SUBSTRATE 
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate)
(Substrate)
LITERATURE
(Substrate)
(Substrate)
COMMENTARY
(Product)
(Product)
LITERATURE
(Product)
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
r=reversible
ir=irreversible
?=not specified
chlorpyrifos oxon + H2O
diethyl phosphate + 3,5,6-trichloropyridin-2-ol
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-
-
?
diisopropyl fluorophosphate + H2O
diisopropyl phosphate + fluoride
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-
-
?
diisopropyl fluorophosphate + H2O
diisopropyl phosphate + fluoride
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-
-
-
?
diisopropyl fluorophosphate + H2O
diisopropyl phosphate + fluoride
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-
-
?
diisopropyl fluorophosphate + H2O
diisopropyl phosphate + fluoride
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-
-
?
diisopropyl fluorophosphate + H2O
diisopropyl phosphate + fluoride
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-
-
-
?
diisopropyl fluorophosphate + H2O
diisopropyl phosphate + fluoride
an analogue molecule of G-type warfare agents
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-
?
diisopropyl phosphofluoridate + H2O
diisopropyl phosphate + fluoride
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SMP30 is important in diisopropyl phosphofluoridate detoxification
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-
?
diisopropyl phosphofluoridate + H2O
diisopropyl phosphate + fluoride
SMP30 is important in diisopropyl phosphofluoridate detoxification
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-
?
additional information
?
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the natural substrates for enzyme are unknown, enzyme may, in nature, be used in peptide metabolism
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-
?
additional information
?
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the enzyme shows broad substrate specificity and is able to degrade organophosphorus compounds with P-O, P-CN, and P-F bonds and is the only enzyme known to cleave the P-S bond, which is characteristic of V-type nerve agents such as VX
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-
?
additional information
?
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the natural substrates for enzyme are unknown
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-
?
additional information
?
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the enzyme shows broad substrate specificity and is able to degrade organophosphorus compounds with P-O, P-CN, and P-F bonds and is the only enzyme known to cleave the P-S bond, which is characteristic of V-type nerve agents such as VX
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-
?
additional information
?
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the natural substrates for enzyme are unknown
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-
?
additional information
?
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enzyme is involved in the synthesis of isoethionate from cysteine
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-
?
additional information
?
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diisopropyl fluorophosphatase acts on a variety of organophosphorus compounds
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-
?
additional information
?
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diisopropyl-fluorophosphatase (DFPase) from Loligo vulgaris is highly stable and robust biocatalyst for the hydrolysis of various chemical warfare agents such as sarin, soman, tabun, but no natural substrate for DFPase has been identified to date
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-
?
additional information
?
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the diisopropylfluorophosphatase (DFPase) from the ganglion and brain of Loligo vulgaris acts on P-F bonds present in some organophosphorus pesticides (OPs)
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-
?
additional information
?
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the diisopropylfluorophosphatase (DFPase) from the ganglion and brain of Loligo vulgaris acts on P-F bonds present in some organophosphorus pesticides (OPs)
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-
?
additional information
?
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enzyme expression in liver decreases androgen-independently of aging
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?
additional information
?
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enzyme expression in liver decreases androgen-independently of aging
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?
additional information
?
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the natural substrates for enzyme are unknown
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?
