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0.39
Coumaphos
-
pH not specified in the publication, temperature not specified in the publication
0.45
diazinon
-
pH not specified in the publication, temperature not specified in the publication
0.048 - 65.45
diisopropyl fluorophosphate
0.46
fensulfothion
-
pH not specified in the publication, temperature not specified in the publication
0.08
methyl parathion
-
pH not specified in the publication, temperature not specified in the publication
0.68
O-cyclohexyl methylphosphonofluoridate
-
pH not specified in the publication, temperature not specified in the publication
0.43
O-ethyl S-(2-diisopropylamino)ethyl methylphosphonothioate
-
pH not specified in the publication, temperature not specified in the publication
0.7 - 1.57
O-isopropylmethylphosphonofluoridate
0.5 - 2.48
O-pinacolyl methylphosphonofluoridate
0.24
parathion
-
pH not specified in the publication, temperature not specified in the publication
additional information
additional information
-
0.048
diisopropyl fluorophosphate
-
pH not specified in the publication, temperature not specified in the publication
2.12
diisopropyl fluorophosphate
mutant enzyme E37A/Y144A/R146A/T195M
2.72
diisopropyl fluorophosphate
wild-type, pH 7.5, 25°C, in nitrogen atmosphere
2.92
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 300 mM 1-amino-2-propanol
2.95
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 300 mM 2-amino-2-methyl-1-propanol
2.99
diisopropyl fluorophosphate
-
-
2.99
diisopropyl fluorophosphate
-
pH not specified in the publication, temperature not specified in the publication
2.99
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 1 mM NaF
3.01
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme
3.08
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 300 mM ethanol
3.1
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant mutant F132Y/L140Y
3.15
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 400 mM monoethanolamine
3.18
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 300 mM methanol
3.2
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant mutant F132Y
3.2
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant mutant L140Y
3.35
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 400 mM diethanolamine
3.38
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 300 mM glycerol
3.57
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 2 mM NaF
3.63
diisopropyl fluorophosphate
pH 10.5, 25°C, recombinant PON1 wild-type enzyme
3.76
diisopropyl fluorophosphate
wild type enzyme
3.87
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 200 mM thiodipropanol and 1 mM NaF
3.93
diisopropyl fluorophosphate
mutant enzyme E37D/Y144A/R16A/T195M
3.97
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 300 mM thiodiglycol
4
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant mutant F132Y/L140Y, with 300 mM triethanolamine
4.06
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 300 mM thiodipropanol and 1 mM NaF
4.1
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 300 mM triethanolamine
4.17
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 300 mM methylamine and 300 mM ethanol
4.2
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant mutant F132Y, with 300 mM triethanolamine
4.21
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 300 mM triisopropanolamine
4.23
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 100 mM thiodipropanol and 1 mM NaF
4.3
diisopropyl fluorophosphate
-
pH 7.5, 22°C
4.32
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 300 mM ethylamine and 300 mM ethanol
4.32
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 400 mM triethanolamine
4.41
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 300 mM diethylamine and 300 mM ethanol
4.44
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 300 mM methylamine
4.45
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 3 mM NaF
4.45
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 300 mM triethylamine and 300 mM ethanol
4.5
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant mutant L140Y, with 300 mM triethanolamine
4.52
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 300 mM triethylamine
4.54
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 200 mM thiodipropanol and 2 mM NaF
4.56
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 300 mM ethylamine
4.58
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 300 mM thiodipropanol and 2 mM NaF
4.61
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 300 mM 3-amino-1-propanol
4.67
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 300 mM diethylamine
4.7
diisopropyl fluorophosphate
pH 10.5, 25°C, recombinant PON1-hFc fusion enzyme
4.77
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 300 mM thiodipropanol
4.87
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 100 mM thiodipropanol and 2 mM NaF
4.89
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 300 mM thiodipropanol and 3 mM NaF
5.04
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 200 mM thiodipropanol and 3 mM NaF
5.58
diisopropyl fluorophosphate
pH 8.0, 25°C, recombinant wild-type enzyme, with 100 mM thiodipropanol and 3 mM NaF
23.36
diisopropyl fluorophosphate
wild-type, presence of 1 mM O,O-dicyclopentylphosphoroamidate, pH 7.5, 25°C, in nitrogen atmosphere
65.45
diisopropyl fluorophosphate
wild-type, presence of 3 mM O,O-dicyclopentylphosphoroamidate, pH 7.5, 25°C, in nitrogen atmosphere
0.7
O-isopropylmethylphosphonofluoridate
-
pH not specified in the publication, temperature not specified in the publication
1.57
O-isopropylmethylphosphonofluoridate
-
pH not specified in the publication, temperature not specified in the publication
0.5
O-pinacolyl methylphosphonofluoridate
-
pH not specified in the publication, temperature not specified in the publication
2.48
O-pinacolyl methylphosphonofluoridate
-
pH not specified in the publication, temperature not specified in the publication
0.058
paraoxon
-
pH not specified in the publication, temperature not specified in the publication
1.27
paraoxon
-
pH not specified in the publication, temperature not specified in the publication
2.48
soman
-
-
additional information
additional information
-
-
-
additional information
additional information
-
-
-
additional information
additional information
-
effects of pH, temperature and ionic strength on KM are studied
-
additional information
additional information
-
comparison of kinetic constants of paraoxon analogs
-
additional information
additional information
Michaelis-Menten kinetics
-
additional information
additional information
-
Michaelis-Menten kinetics
-
additional information
additional information
Michaelis-Menten kinetic analysis, substrate diisopropyl fluorophosphate in presence of aminoalcohol activators
-
additional information
additional information
reaction kinetics of wild-type and mutant enzymes, overview
-