Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

3.1.8.1: aryldialkylphosphatase

This is an abbreviated version!
For detailed information about aryldialkylphosphatase, go to the full flat file.

Word Map on EC 3.1.8.1

Reaction

An aryl dialkyl phosphate
+
H2O
=
dialkyl phosphate
 +
an aryl alcohol

Synonyms

A-esterase, A7Q26_23485, aminopeptidase P, AMPP, aryldialkylphosphatase, arylesterase, aryltriphosphatase, bacterial phosphotriesterase, DFPase, diisopropyl fluorophosphatase, esterase B1, esterase E4, esterase, organophosphate, esterase, paraoxon, esterase, pirimiphos-methyloxon, G3C9 rePON1, h-PON1, HAD, haloalkylphosphorus hydrolase, HDL-associated esterase/lactonase paraoxonase 1, HDL-PON1, high activity paraoxonase, high-density lipoprotein-associated esterase/lactonase, human paraoxonase 1, HuPON1, inner membrane protein YiaH, lactonase SsoPox, lactonase/phosphotriesterase, low activity paraoxonase, methyl parathion hydrolase, More, Mph, mPHP, OP hydrolase, OP-hydrolase, OP-hydrolyzing enzyme, OPA anhydrase, opd, OpdA, OpdD, OPH, OPHC2, organophosphate hydrolase, organophosphorous hydrolase, organophosphorus acid anhydrase, organophosphorus hydrolase, organophosphorus pesticide hydrolase, organophosphorus-hydrolyzing enzyme, paraoxon hydrolase, paraoxonase, paraoxonase 1, paraoxonase 1A, paraoxonase 3, paraoxonase-1, paraoxonase-2, paraoxonase1, parathion hydrolase, phosphotriesterase, phosphotriesterase homology protein, phosphotriesterase-like lactonase, PHP, pirimiphos-methyloxon esterase, PLL, PO.ase, PON, PON 1, PON-1, PON-aryl, PON-para, PON1, PON1A, PON2, PON3, POX, PTE, PTE S5, Rv0230c, SACI2140, Saci_2140, SacPox, Sb-PTE, serum paraoxonase, serum paraoxonase 1, SisLac, SisPox, Sso, SSO2522, SsoPox, type A paraoxonase, type B paraoxonase, VmoLac, Vmut2255, VmutPLL

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.8 Phosphoric-triester hydrolases
                3.1.8.1 aryldialkylphosphatase

Turnover Number

Turnover Number on EC 3.1.8.1 - aryldialkylphosphatase

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
TURNOVER NUMBER [1/s]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.83
(1E)-but-1-en-1-yl dibutyl phosphate
pH 9.0, 25°C
1.1 - 51
(S)-[2-[di(propan-2-yl)amino]ethyl] O,O-diethyl phosphorothioate
5
1,2,2-trimethylpropyl methylphosphonofluoridate
-
-
0.27 - 9160
2,4-dinitrophenyl diethyl phosphate
0.062 - 950
2,6-difluorophenyl diethyl phosphate
3.7
2-fluoro 4-nitrophenyl diethyl phosphate
pH 8.0
11080
2-fluoro-4-nitrophenyl diethyl phosphate
pH 8.0, genetic variant PON1 G2E6
10.2 - 1477
3,5-dinitrophenyl diethyl phosphate
0.178 - 1610
3-cyanophenyl diethyl phosphate
13.9
3-fluoro 4-nitrophenyl diethyl phosphate
pH 8.0
11680
3-fluoro-4-nitrophenyl diethyl phosphate
pH 8.0, genetic variant PON1 G2E6
0.0011 - 656
3-fluorophenyl diethyl phosphate
0.076 - 840
3-nitrophenyl diethyl phosphate
13
4-acetoxy acetophenone
pH 8.0, genetic variant PON1 G2E6
0.41 - 8.5
4-acetylphenyl (2R)-3,3-dimethylbutan-2-yl (R)-methylphosphonate
0.21 - 1.5
4-acetylphenyl (2R)-3,3-dimethylbutan-2-yl (S)-methylphosphonate
0.016 - 2.9
4-acetylphenyl (2S)-3,3-dimethylbutan-2-yl (S)-methylphosphonate
17 - 174
4-acetylphenyl (R)-2-methylpropyl methylphosphonate
3 - 166
4-acetylphenyl (S)-2-methylpropyl methylphosphonate
20 - 110
4-acetylphenyl 2-methylpropyl (R)-methylphosphonate
12 - 100
4-acetylphenyl 2-methylpropyl (S)-methylphosphonate
0.81 - 150
4-acetylphenyl cyclohexyl (R)-methylphosphonate
0.14 - 19
4-acetylphenyl cyclohexyl (S)-methylphosphonate
0.36
4-acetylphenyl cyclohexyl methyl (R)-phosphate
pH 8.5, 30°C
0.38
4-acetylphenyl cyclohexyl methyl (S)-phosphate
pH 8.5, 30°C
7.3 - 150
4-acetylphenyl ethyl (R)-methylphosphonate
110 - 670
4-acetylphenyl ethyl (S)-methylphosphonate
18 - 250
4-acetylphenyl propan-2-yl (R)-methylphosphonate
7.4 - 370
4-acetylphenyl propan-2-yl (S)-methylphosphonate
0.8
4-carbamoylphenyl diethyl phosphate
pH and temperature not specified in the publication
0.0008 - 848
4-chlorophenyl diethyl phosphate
0.4 - 7495
4-cyanophenyl diethyl phosphate
0.44 - 8080
4-diethyl phosphate acetophenone
0.47 - 12620
4-diethyl phosphate benzaldehyde
5485
4-diethyl phosphate methyl benzoate
pH 8.0, genetic variant PON1 G2E6
4.8 - 10520
4-nitrophenyl diethyl phosphate
166
5-(thiobutyryl)butyrolactone
pH 8.0, recombinant wild-type PON1 genetic variant G2E6
0.02
Benzyl acetate
about, pH 8.0, genetic variant PON1 G2E6
2.2 - 30900
chlorpyrifos
0.28
CMP-coumarin
pH 8.3, 25°C
949
Coumaphos
-
pH 7.2, 25°C
2.5
cyclohexyl ethyl 4-nitrophenyl (R)-phosphate
pH 8.5, 30°C
2.8
cyclohexyl ethyl 4-nitrophenyl (S)-phosphate
pH 8.5, 30°C
6
cyclohexyl methyl 4-nitrophenyl (R)-phosphate
pH 8.5, 30°C
1.11
cyclohexyl methyl 4-nitrophenyl (S)-phosphate
pH 8.5, 30°C
0.38
cyclohexyl methyl phenyl (R)-phosphate
pH 8.5, 30°C
0.0006 - 650
demeton-S
13.16 - 69.44
demeton-S methyl
0.045 - 0.36
dibutyl 2,2,3,3-tetrafluorobutyl phosphate
0.043
dibutyl 3,3-difluorobutyl phosphate
pH 9.0, 25°C
2.5
dibutyl 4-acetophenyl phosphate
pH and temperature not specified in the publication
7.5
dibutyl 4-nitrophenyl phosphate
pH and temperature not specified in the publication
4.4
dibutyl phenyl phosphate
pH and temperature not specified in the publication
71
diethyl 2,4,6-trifluorophenyl phosphate
pH and temperature not specified in the publication
13
diethyl 2,4-difluorophenyl phosphate
pH and temperature not specified in the publication
93
diethyl 2,6-difluoro-4-nitrophenyl phosphate
pH and temperature not specified in the publication
40
diethyl 2-fluoro-4-nitrophenyl phosphate
pH and temperature not specified in the publication
21
diethyl 2-fluorophenyl phosphate
pH and temperature not specified in the publication
107
diethyl 3-fluoro-4-nitrophenyl phosphate
pH and temperature not specified in the publication
81
diethyl 3-fluorophenyl phosphate
pH and temperature not specified in the publication
0.6
diethyl 4-acetophenyl phosphate
pH and temperature not specified in the publication
0.13 - 40
diethyl 4-chlorophenyl phosphate
1.1 - 2.4
diethyl 4-chlorophenyl thiophosphate
93
diethyl 4-cyanophenyl phosphate
pH and temperature not specified in the publication
78
diethyl 4-fluorophenyl phosphate
pH and temperature not specified in the publication
31
diethyl 4-formylphenyl phosphate
pH and temperature not specified in the publication
2.5
diethyl 4-methoxyphenyl phosphate
pH and temperature not specified in the publication
6.5 - 2500
diethyl 4-nitrophenyl phosphate
4.3 - 16.2
diethyl paraoxon
167
diethyl pentafluoro-phenyl phosphate
pH and temperature not specified in the publication
71
diethyl phenyl phosphate
pH and temperature not specified in the publication
0.104 - 2230
diethyl-paraoxon
1.3
diethylumbelliferyl phosphate
-
pH 7.5, 25°C, recombinant mutant enzyme G137D
698
dihydrocoumarin
-
recombinant PON3
41
diisopropylfluorophosphate
-
-
9.1
dimethyl 4-nitrophenyl phosphate
pH 8.5, 30°C
0.1 - 10.7
dimethyl-paraoxon
0.24
ethyl acetate
pH 8.0, genetic variant PON1 G2E6
0.115
ethyl paraoxon
-
at 35°C, pH 9.0
0.00108
ethyl-paraoxon
pH 8.0, 70°C
56
isopropylmethylphosphonofluoridate
-
-
0.00089 - 160
malathion
6.3
methyl 4-nitrophenyl phenyl (R)-phosphate
pH 8.5, 30°C
0.6
methyl 4-nitrophenyl phenyl (S)-phosphate
pH 8.5, 30°C
5
methyl 4-nitrophenyl propan-2-yl (R)-phosphate
pH 8.5, 30°C
2.05
methyl 4-nitrophenyl propan-2-yl (S)-phosphate
pH 8.5, 30°C
3.2
methyl 4-[(diethoxyphosphoryl)oxy]benzoate
pH and temperature not specified in the publication
9
methyl bis(4-nitrophenyl) phosphate
pH 8.5, 30°C
0.00783 - 342
methyl paraoxon
0.0011 - 1152
methyl parathion
2300
methylparathion
-
pH 8.0, 37°C, recombinant His6-tagged wild-type OPH
0.42
O,O,S-tributyl phosphorothioate
pH 9.0, 25°C
0.1
O-isobutyl-S-[2-(diethylamino)ethyl]methylphosphonothioic acid
-
in 50 mM Tris-HCl buffer, 10 mM CaCl2, pH 7.4
0.0008 - 11700
paraoxon
0.12 - 1098
parathion
0.6 - 678
pentafluorophenyl diethyl phosphate
89 - 1236
phenyl acetate
771
phosmet
-
pH 7.2, 25°C
0.55 - 11.72
RP-O-ethyl methylphosphonyl-3-cyano-7-hydroxy-4-methylcoumarin
0.167 - 4.95
RP-O-n-propyl methylphosphonyl-3-cyano-7-hydroxy-4-methylcoumarin
0.007 - 0.15
S-(2-[di(propan-2-yl)amino]ethyl)O-ethyl methylphosphonothioate
15 - 300
sarin
2.2 - 89
soman
0.15 - 0.5
SP-O-ethyl methylphosphonyl-3-cyano-7-hydroxy-4-methylcoumarin
1.83 - 6.467
SP-O-n-propyl methylphosphonyl-3-cyano-7-hydroxy-4-methylcoumarin
additional information
additional information
-
-