3.1.7.6: farnesyl diphosphatase

This is an abbreviated version!
For detailed information about farnesyl diphosphatase, go to the full flat file.

farnesyl diphosphatase, farnesyl pyrophosphatase, FPPase, Pho8DELTA62, pNPP/FPP phosphatase

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Results	in table
5	Activating Compound
6	AA Sequence
3	Expression
3	IC50 Value
22	Inhibitors
4	Ki Value [mM]
4	KM Value [mM]
5	Localization
8	Metals/Ions
1	Molecular Weight [Da]
3	Natural Substrates/ Products (Substrates)
9	Organism
4	Pathway
7	pH Optimum
6	pH Range
1	Protein Variants
2	Purification (Commentary)
1	Reaction
9	Reference
8	Source Tissue
1	Specific Activity [micromol/min/mg]
12	Substrates and Products (Substrate)
1	Subunits
7	Synonyms
1	Systematic Name
2	Temperature Optimum [°C]

pH Range on EC 3.1.7.6 - farnesyl diphosphatase

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4.5 - 6.8

pH 4.5: about 55% of maximal activity, pH 6.8: about 60% of maximal activit, soluble enzyme

5 - 6.2

pH 5.0: about 45% of maximal activity, pH 6.2: about 75% of maximal activity

5 - 6.8

pH 5.0: about 60% of maximal activity, pH 6.8: about 65% of maximal activit, microsomal enzyme

6.3 - 7

pH 6.3: about 80% of maximal activity, pH 7.0: about about 70% of maximal activity

maximal activity at pH 7.0, less than 1% of maximal activity at pH 6.0, less than 10% of maximal activity at pH 8.5

8.5 - 9.1

pH 8.5: about 40% of maximal activity, pH 9.1: about 65% of maximal activity