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3.1.6.18: glucuronate-2-sulfatase

This is an abbreviated version!
For detailed information about glucuronate-2-sulfatase, go to the full flat file.

Reaction

2-O-sulfo-D-glucuronate
+
H2O
=
sulfate
+
D-glucuronate

Synonyms

ARSK, arylsulfatase K, GAS, glucuronate 2-sulfatase, glucurono-2-sulfatase, sulfatase, glucuronate 2-

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.6 Sulfuric-ester hydrolases
                3.1.6.18 glucuronate-2-sulfatase

Inhibitors

Inhibitors on EC 3.1.6.18 - glucuronate-2-sulfatase

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INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
Cu2+
-
above pH 4.2, activation over pH-range 3-4.2, glucuronic acid 2-sulfate-2,5-anhydro-D-mannitol 6-sulfate as substrate
Glucuronic acid 2,5-anhydro-D-mannitol 6-sulfate
-
product inhibition
Glucuronic acid 2-sulfate-2,5-anhydro-D-mannitol 6-sulfate
-
i.e. GSMS, substrate inhibition, above 0.004 mM
Glucuronic acid 2-sulfate-2,5-anhydro-D-talitol 6-sulfate
-
i.e. GSTS, substrate inhibition, above 0.004 mM
NaH2PO4
O-alpha-Iduronic acid 2-sulfate-1,4-O-(2,5)-anhydro-D-mannitol 6-sulfate
-
-
SO42-