Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

3.1.6.1: arylsulfatase (type I)

This is an abbreviated version!
For detailed information about arylsulfatase (type I), go to the full flat file.

Word Map on EC 3.1.6.1

Reaction

an aryl sulfate
+
H2O
=
a phenol
 +
sulfate

Synonyms

4-methylumbelliferyl sulfatase, ARS, ARS-A, ARS-B, ARSA, ARSB, ARSE, ARSK, ary 423, Aryl-sulfate sulphohydrolase, arylsufatase B, arylsulfatase, arylsulfatase A, arylsulfatase B, arylsulfatase E, arylsulfatase Es-2, arylsulfatase G, arylsulfatase gene, arylsulfatase III, arylsulfatase J, arylsulfatase K, arylsulfatase type VI, arylsulfate sulfohydrolase II, arylsulfohydrolase, arylsulphatase, arylsulphatase A, AS-A, ASG, AstA, AtsA, estrogen sulfatase, KIAA1001, nitrocatechol sulfatase, p-nitrophenyl sulfatase, P70, PAS, phenolsulfatase, phenylsulfatase, sulfatase, sulfatase, aryl-

ECTree

     3 Hydrolases
         3.1 Acting on ester bonds
             3.1.6 Sulfuric-ester hydrolases
                3.1.6.1 arylsulfatase (type I)

Metals Ions

Metals Ions on EC 3.1.6.1 - arylsulfatase (type I)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
METALS and IONS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
Co2+
1 mM, 119% of initial activity, mutant H260L
Fe2+
1 mM, more than 10% increase in specific activity
Mg2+
-
can partially replace Ca2+
Mn2+
10 mM, 230% of initial activity, mutant H260L
Na+
1 mM, 108% of initial activity, mutant H260L
NH4+
-
25 mM, 60% activation
phosphate
-
activates hydrolysis of 4-nitrophenyl sulfate with the beta enzyme
Sr2+
-
can partially replace Ca2+
sulfate
-
activates hydrolysis of 4-nitrophenyl sulfate with the beta enzyme
additional information
neither inhibitory nor activating: Ca2+, K+, Ba2+, Mg2+, Mn2+ and Sn2+